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The map label for this gene is ubiH [C]

Identifier: 89052916

GI number: 89052916

Start: 427308

End: 428435

Strand: Reverse

Name: ubiH [C]

Synonym: Jann_0425

Alternate gene names: 89052916

Gene position: 428435-427308 (Counterclockwise)

Preceding gene: 89052921

Following gene: 89052910

Centisome position: 9.92

GC content: 63.39

Gene sequence:

>1128_bases
TTGGATGCCCTTCCTGCGCAGACCCGCGAAGAGACGGGCTTTGACGGGCGCGCCTATGCGCTGGCTTTGGCGTCTGTGCG
GATGCTGGATGCGCTGGGGATCTGGAATCAGGTCGAGGATCACGCACAGCCGATGTTGGAGATTAAAGCCTCCGACGGGC
GGGCCGGTGAAGGGGCCGCGCCGTTTTTCCTGCACTTCGATCATGCCGAGATCGAGGAAGGCCCGATGGGTCACATGCTG
GAGGACCGCTACCTGCGGCGCGCATTGATGGCCGCGATGGAGGCGTCATCACTGGTCGCGCACCGCGCAGCATCGCGTGT
TTTGTCGCAAGATACCAATGGGATGGCATCCGTCACGTTGGACGGCGGAGAGGTCCTGCGCGGGCGGCTTCTGATCGGCG
CTGATGGCAAACGATCCGGCGTGGCGGAGCGAGCTGGCATCAGGCGGATGGGCTGGGATTACAACCAAACGGCATTGGTC
TGCGCCGTCGACCATGACCGTCCCCACAACGGCATTGCGCATCAGTTCTTCATGCCGGGTGGACCGCTGGCAATCTTGCC
GCTGCCGGGCAACAGATCCTCCATCGTCTGGTCAGAATCTGAGCCGCGCGCCAGCGAGTTGGCGGCAGCGGATGATGACA
CGTTCATGGATGCGCTGCGCCCCGCGTTTGGGGACTTCCTAGGCAATATTTCATTGACAGGACAACGACATAGCTACCCG
CTGTCGCTGTCCCTCGCGCAGGCCTTTGTGGCCGAAAAACTGGCCCTTGTGGGTGATGCCGCCCATGGTGTGCACCCGAT
TGCCGGGCAAGGTCTGAACCTTGGTCTACGAGACGTCAGTGCCCTTGCGGAGACCCTCGCCGATGCCAAACGGCGCGGAG
AAGATTTCGCGCGGCGCGACGTGCTGGATCGCTATCAGCAATGGCGGCGCTTCGATACGGCGGGGCTTGCGGTCGCGACC
GATAGCGTGAACCGCCTGTTCTCCAACGACAATCCGGCCGTGCGGGCGATCCGGGATATCGGTATGGGGGCCATCGGCGC
GCTGCCAACCTTGCGCCGCCGTTTCATTCGGGAGGCTGCCGGCTTGACCGGAGACCTCCCGCGTTTGATGCAAGGTCGGA
CCCTGTAG

Upstream 100 bases:

>100_bases
TATGGAACAGCTTGATGCAGATATTCTGATTGTTGGCGGGGGTTTAAACGGCCCCTGTCTTGCCCTGGCCTGCGCGCAAG
CGGGGCTGTCTTCGGTCGTC

Downstream 100 bases:

>100_bases
ATCGCCCAAAAGGGCATCAGGGGTATATCAATCGTATATCAATTTCGAAAATGAGGGGTGCCGGTCCGTCGCCCAGTCGC
AGATCCTGTCGACTGAGGGC

Product: 2-octaprenyl-6-methoxyphenol hydroxylase / 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MDALPAQTREETGFDGRAYALALASVRMLDALGIWNQVEDHAQPMLEIKASDGRAGEGAAPFFLHFDHAEIEEGPMGHML
EDRYLRRALMAAMEASSLVAHRAASRVLSQDTNGMASVTLDGGEVLRGRLLIGADGKRSGVAERAGIRRMGWDYNQTALV
CAVDHDRPHNGIAHQFFMPGGPLAILPLPGNRSSIVWSESEPRASELAAADDDTFMDALRPAFGDFLGNISLTGQRHSYP
LSLSLAQAFVAEKLALVGDAAHGVHPIAGQGLNLGLRDVSALAETLADAKRRGEDFARRDVLDRYQQWRRFDTAGLAVAT
DSVNRLFSNDNPAVRAIRDIGMGAIGALPTLRRRFIREAAGLTGDLPRLMQGRTL

Sequences:

>Translated_375_residues
MDALPAQTREETGFDGRAYALALASVRMLDALGIWNQVEDHAQPMLEIKASDGRAGEGAAPFFLHFDHAEIEEGPMGHML
EDRYLRRALMAAMEASSLVAHRAASRVLSQDTNGMASVTLDGGEVLRGRLLIGADGKRSGVAERAGIRRMGWDYNQTALV
CAVDHDRPHNGIAHQFFMPGGPLAILPLPGNRSSIVWSESEPRASELAAADDDTFMDALRPAFGDFLGNISLTGQRHSYP
LSLSLAQAFVAEKLALVGDAAHGVHPIAGQGLNLGLRDVSALAETLADAKRRGEDFARRDVLDRYQQWRRFDTAGLAVAT
DSVNRLFSNDNPAVRAIRDIGMGAIGALPTLRRRFIREAAGLTGDLPRLMQGRTL
>Mature_375_residues
MDALPAQTREETGFDGRAYALALASVRMLDALGIWNQVEDHAQPMLEIKASDGRAGEGAAPFFLHFDHAEIEEGPMGHML
EDRYLRRALMAAMEASSLVAHRAASRVLSQDTNGMASVTLDGGEVLRGRLLIGADGKRSGVAERAGIRRMGWDYNQTALV
CAVDHDRPHNGIAHQFFMPGGPLAILPLPGNRSSIVWSESEPRASELAAADDDTFMDALRPAFGDFLGNISLTGQRHSYP
LSLSLAQAFVAEKLALVGDAAHGVHPIAGQGLNLGLRDVSALAETLADAKRRGEDFARRDVLDRYQQWRRFDTAGLAVAT
DSVNRLFSNDNPAVRAIRDIGMGAIGALPTLRRRFIREAAGLTGDLPRLMQGRTL

Specific function: Oxygenase That Introduces The Hydroxyl Group At Carbon Four Of 2-Octaprenyl-6-Methoxyphenol Resulting In The Formation Of 2-Octaprenyl-6-Methoxy-1,4-Benzoquinone. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=402, Percent_Identity=29.6019900497512, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI32967307, Length=338, Percent_Identity=31.9526627218935, Blast_Score=166, Evalue=4e-41,
Organism=Escherichia coli, GI1789274, Length=344, Percent_Identity=36.3372093023256, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789273, Length=361, Percent_Identity=35.7340720221607, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1786883, Length=362, Percent_Identity=33.9779005524862, Blast_Score=184, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI25146631, Length=376, Percent_Identity=28.1914893617021, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321694, Length=293, Percent_Identity=27.9863481228669, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19920760, Length=387, Percent_Identity=26.6149870801034, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 40582; Mature: 40582

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALPAQTREETGFDGRAYALALASVRMLDALGIWNQVEDHAQPMLEIKASDGRAGEGAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
PFFLHFDHAEIEEGPMGHMLEDRYLRRALMAAMEASSLVAHRAASRVLSQDTNGMASVTL
CEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
DGGEVLRGRLLIGADGKRSGVAERAGIRRMGWDYNQTALVCAVDHDRPHNGIAHQFFMPG
CCHHEEEEEEEEECCCCCCCCHHHHCHHHCCCCCCCEEEEEEECCCCCCCCCCEEEECCC
GPLAILPLPGNRSSIVWSESEPRASELAAADDDTFMDALRPAFGDFLGNISLTGQRHSYP
CCEEEEECCCCCCEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCC
LSLSLAQAFVAEKLALVGDAAHGVHPIAGQGLNLGLRDVSALAETLADAKRRGEDFARRD
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLDRYQQWRRFDTAGLAVATDSVNRLFSNDNPAVRAIRDIGMGAIGALPTLRRRFIREAA
HHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GLTGDLPRLMQGRTL
CCCCCCHHHHCCCCC
>Mature Secondary Structure
MDALPAQTREETGFDGRAYALALASVRMLDALGIWNQVEDHAQPMLEIKASDGRAGEGAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
PFFLHFDHAEIEEGPMGHMLEDRYLRRALMAAMEASSLVAHRAASRVLSQDTNGMASVTL
CEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
DGGEVLRGRLLIGADGKRSGVAERAGIRRMGWDYNQTALVCAVDHDRPHNGIAHQFFMPG
CCHHEEEEEEEEECCCCCCCCHHHHCHHHCCCCCCCEEEEEEECCCCCCCCCCEEEECCC
GPLAILPLPGNRSSIVWSESEPRASELAAADDDTFMDALRPAFGDFLGNISLTGQRHSYP
CCEEEEECCCCCCEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCC
LSLSLAQAFVAEKLALVGDAAHGVHPIAGQGLNLGLRDVSALAETLADAKRRGEDFARRD
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLDRYQQWRRFDTAGLAVATDSVNRLFSNDNPAVRAIRDIGMGAIGALPTLRRRFIREAA
HHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GLTGDLPRLMQGRTL
CCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]