Click here to switch to the map view.

The map label for this gene is znuA [H]

Identifier: 89052803

GI number: 89052803

Start: 319760

End: 320848

Strand: Reverse

Name: znuA [H]

Synonym: Jann_0312

Alternate gene names: 89052803

Gene position: 320848-319760 (Counterclockwise)

Preceding gene: 89052807

Following gene: 89052793

Centisome position: 7.43

GC content: 61.43

Gene sequence:

>1089_bases
ATGTCCAGAAAGCTTCTATCCATTTCCGCCACGGCAGCCCTGATGGGCGGCACGGCGATGGCCGACGTGCCCAGCGTGGC
CGTCGACATCACGCCGGTTCATTCCTTGGTGGCGCGGGTCATGGACGGAGTTGGGACGCCGAACCTGATCGTGCAGCCGG
GCGCCTCGCCCCATGAATATAGCCTCCGCCCGTCCGAGGCCACTGCCCTGCAAGAGGCCGATCTGGTGTTCTGGATGGGT
GAAGATCTGACACCCTGGATGGAAGATGCGGTCGAAACTCTGGCGGAAGGGGCCATGATCACGACCCTTCTGGAGGCCGA
CGGAACCACCCTTCTGGACTTCCGGGAGGGCGCGCTGTTCGAGGCCCATGACCATGAAGATCACGCCGGTGACGGAGAGC
ATGATGATCATGATCATGACGACGACCACGATCACGAAGCGCATGCGGAGGAAGAAGGGCATGATCACGACGGACACGGT
GATGAAAACTATGCCGAAGAGGGCGCGCACGAGGAGTATGACCACGAAGACCATGCAGAACATGACGACCACGAGGGGCA
TGAAGGCCACGACCATGGCGAGCATGATCCCCATGCCTGGCTCTCCCCTCAAAACGCCAGCACATGGCTTAACCTGATCG
CGTCACAGCTGTCCGCCGCCGACCCCGAAAATGCCGGCGCTTACTTCGCCAATGCCGCCGCCGCACGCGAAGAGATGGAG
GCGCTGTCTGCCGAGATCTCAGCCACACTTGATCCGGTGCGCGGCGGCAGCTTCATCGTGTTCCACGACGCCTACCAATA
CTTTGAAGTCGATTTCGACTTCCCCGCGGCCGGTGCGATATCGTTGAGCGATGCGACCGACCCGAGCCCGGCGCGGATCG
CTGAAATTCAAGGTCGGATCCGGGACGAAGGCATCGATTGCGTTCTGGCCGAACCGCAATTCAACCCGGGCATCGTCGAT
GTGGTCCTTGACGGGACTGAGGCCAACACCGGCGTGATTGACCCGCTTGGCGCGTCGCTGGAGCCTGGGCCGGATCTCTA
TCCGCAATTGCTGCGCAATATGGCCACAACACTGGCCGATTGCCTGTAA

Upstream 100 bases:

>100_bases
GGCGTATCATTTCCCGCGTCTTGAGAGCGCGCGTCACTTGTCATGTTATTTCATATCAGTTATGCCGCCAATAATGTTAT
AAGATCACGTGGAGAGACCT

Downstream 100 bases:

>100_bases
CTATTTGCTTGCCTGCGCCCGTTCGCAACTAACGGGCGTAGCGCAGGGTCCGGACCGGTTCTATTGGGTGGTTTGGATAG
AGTACGGTCGCCTTGGACCA

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSRKLLSISATAALMGGTAMADVPSVAVDITPVHSLVARVMDGVGTPNLIVQPGASPHEYSLRPSEATALQEADLVFWMG
EDLTPWMEDAVETLAEGAMITTLLEADGTTLLDFREGALFEAHDHEDHAGDGEHDDHDHDDDHDHEAHAEEEGHDHDGHG
DENYAEEGAHEEYDHEDHAEHDDHEGHEGHDHGEHDPHAWLSPQNASTWLNLIASQLSAADPENAGAYFANAAAAREEME
ALSAEISATLDPVRGGSFIVFHDAYQYFEVDFDFPAAGAISLSDATDPSPARIAEIQGRIRDEGIDCVLAEPQFNPGIVD
VVLDGTEANTGVIDPLGASLEPGPDLYPQLLRNMATTLADCL

Sequences:

>Translated_362_residues
MSRKLLSISATAALMGGTAMADVPSVAVDITPVHSLVARVMDGVGTPNLIVQPGASPHEYSLRPSEATALQEADLVFWMG
EDLTPWMEDAVETLAEGAMITTLLEADGTTLLDFREGALFEAHDHEDHAGDGEHDDHDHDDDHDHEAHAEEEGHDHDGHG
DENYAEEGAHEEYDHEDHAEHDDHEGHEGHDHGEHDPHAWLSPQNASTWLNLIASQLSAADPENAGAYFANAAAAREEME
ALSAEISATLDPVRGGSFIVFHDAYQYFEVDFDFPAAGAISLSDATDPSPARIAEIQGRIRDEGIDCVLAEPQFNPGIVD
VVLDGTEANTGVIDPLGASLEPGPDLYPQLLRNMATTLADCL
>Mature_361_residues
SRKLLSISATAALMGGTAMADVPSVAVDITPVHSLVARVMDGVGTPNLIVQPGASPHEYSLRPSEATALQEADLVFWMGE
DLTPWMEDAVETLAEGAMITTLLEADGTTLLDFREGALFEAHDHEDHAGDGEHDDHDHDDDHDHEAHAEEEGHDHDGHGD
ENYAEEGAHEEYDHEDHAEHDDHEGHEGHDHGEHDPHAWLSPQNASTWLNLIASQLSAADPENAGAYFANAAAAREEMEA
LSAEISATLDPVRGGSFIVFHDAYQYFEVDFDFPAAGAISLSDATDPSPARIAEIQGRIRDEGIDCVLAEPQFNPGIVDV
VLDGTEANTGVIDPLGASLEPGPDLYPQLLRNMATTLADCL

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=347, Percent_Identity=27.0893371757925, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 38932; Mature: 38801

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKLLSISATAALMGGTAMADVPSVAVDITPVHSLVARVMDGVGTPNLIVQPGASPHEY
CCCCEEEHHHHHHHHCCCHHHCCCCEEEECCHHHHHHHHHHHCCCCCCEEECCCCCCCCC
SLRPSEATALQEADLVFWMGEDLTPWMEDAVETLAEGAMITTLLEADGTTLLDFREGALF
CCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCHHEEEEECCCCCEEEEECCCCEE
EAHDHEDHAGDGEHDDHDHDDDHDHEAHAEEEGHDHDGHGDENYAEEGAHEEYDHEDHAE
ECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
HDDHEGHEGHDHGEHDPHAWLSPQNASTWLNLIASQLSAADPENAGAYFANAAAAREEME
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ALSAEISATLDPVRGGSFIVFHDAYQYFEVDFDFPAAGAISLSDATDPSPARIAEIQGRI
HHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHH
RDEGIDCVLAEPQFNPGIVDVVLDGTEANTGVIDPLGASLEPGPDLYPQLLRNMATTLAD
HCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
CL
CC
>Mature Secondary Structure 
SRKLLSISATAALMGGTAMADVPSVAVDITPVHSLVARVMDGVGTPNLIVQPGASPHEY
CCCEEEHHHHHHHHCCCHHHCCCCEEEECCHHHHHHHHHHHCCCCCCEEECCCCCCCCC
SLRPSEATALQEADLVFWMGEDLTPWMEDAVETLAEGAMITTLLEADGTTLLDFREGALF
CCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCHHEEEEECCCCCEEEEECCCCEE
EAHDHEDHAGDGEHDDHDHDDDHDHEAHAEEEGHDHDGHGDENYAEEGAHEEYDHEDHAE
ECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
HDDHEGHEGHDHGEHDPHAWLSPQNASTWLNLIASQLSAADPENAGAYFANAAAAREEME
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ALSAEISATLDPVRGGSFIVFHDAYQYFEVDFDFPAAGAISLSDATDPSPARIAEIQGRI
HHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHH
RDEGIDCVLAEPQFNPGIVDVVLDGTEANTGVIDPLGASLEPGPDLYPQLLRNMATTLAD
HCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
CL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA