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The map label for this gene is sdaA [H]

Identifier: 89052807

GI number: 89052807

Start: 323077

End: 324489

Strand: Reverse

Name: sdaA [H]

Synonym: Jann_0316

Alternate gene names: 89052807

Gene position: 324489-323077 (Counterclockwise)

Preceding gene: 89052808

Following gene: 89052803

Centisome position: 7.51

GC content: 63.06

Gene sequence:

>1413_bases
ATGTTTCTGAGCATCTTCGACATCTTCAAGGTCGGCATCGGCCCCTCCTCCTCCCACACGATGGGCCCCATGACCGCTGC
CGCGCGGTTCCTGGAGGATCTGCGCAACGGGCGCGAGAAGGAGCCGGGCGCAGGCGAATTGGGTGGTTTGGGGTGTTCAC
TACACGGCTCCCTGGCGTTCACCGGCAAGGGGCACGCGACGGATCGCGCCGTGATCCTGGGATTTGCCGGGTTTGAGCCT
GCCACCCTGGACCCTGATCAGGCGGAAGCGCTTGAGACCGAAATCCGCGCCTCTGGCATCGTCACACCACCGGGCCTTCC
GCCGCTGAAATTCGCGCCCGATGCGGACCTGATCTTCGATTATGACACCACGTTGCCTGGCCACGCCAATGGCATGATCC
TGCGCGCCTATGACACCAACGGGCATCTTTATCTGGAGGAGACCTATTACTCCATCGGCGGTGGCTTTGTGGTGACGGAG
AAAGAGCTGAATGTCCAAGGCGACGGCCCAGAGGCGCTGCACGCCGAGAAGGAAGAGGCCGGGTTCCCCCATCCGTTCGG
ATCTGCGGTTGAGATGCTGGCGATGGGGGCCAGGACCGGCAAGACAATCGCCCAGATGAAGTGGGAGAATGAGGCCGCTT
TTGCCCCCCGCGGCCAAGTGACGACGCAACTTGATGCGATCTGGACCGCCATGGACGATTGCATCGACCGCGGCTTGCGG
ATGGAGGGGGAGCTGCCCGGCGGCCTGATGGTCAAGCGCCGCGCCAAGGCGATCTACGATCAATTGAAGGCAGAGGCGGG
CACCAATCAGGCCCAACCCCATGTCGCCAACGATTGGCTGTCGGTCTATGCAATGGCGGTGAACGAGGAGAACGCCGCAG
GCGGGCGCGTCGTGACATCCCCCACAAACGGCGCGGCGGGGGTCCTTCCCGCTGTCCTGCGCTACTACCGCGACCATTGC
ATCGGCGCGACCGAAGATGGCCTGCGGGATTTCATGATGACCGCCGCCGCGATTGGCGGGCTGATCAAGCACAACGCCTC
CATTTCCGGCGCCGAAGTTGGGTGTCAGGGGGAGGTTGGCAGCGCGTCGGCTATGGCGGCCGCTGGATTGTGCGCTGCGT
TGGGCGGCACCAATGCACAGGTGGAGAACGCCGCTGAGATTGCCCTGGAACATCACATGGGCATGACCTGCGATCCAGTC
GCTGGCTTGGTGCAAGTGCCGTGTATTGAGCGGAACGGATTGGGGGCGATCAAAGCCGTATCTGCGGCGTCCCTGGCCCT
TCGCGGCGACGGCACGCATTTCATGCCGCTGGACAACTGCATTGAAGCGATGCGCCAGACGGGCCTCGACATGAATACGA
AGTATAAAGAGACGAGCGAAGGCGGATTGGCGGTCAACCTGCCCCAGTGCTGA

Upstream 100 bases:

>100_bases
GCAGCCTTTCGGGGAATGTCAGCGCATATCGTCGGTCCCGCCTCTCATCCCGTCGGTCTCGCCCCTTGGGTTGGAGCGGC
AGACACGCTAACTCAGGCGC

Downstream 100 bases:

>100_bases
GGGCGCTCACCTTAGCTGGAGTGTCGAAGCTCGGATCGCCGAACACCATTCAGCAGACAGACCTGCCATGGGCGCGACTG
TACCAGGTGATTATTTTCTC

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MFLSIFDIFKVGIGPSSSHTMGPMTAAARFLEDLRNGREKEPGAGELGGLGCSLHGSLAFTGKGHATDRAVILGFAGFEP
ATLDPDQAEALETEIRASGIVTPPGLPPLKFAPDADLIFDYDTTLPGHANGMILRAYDTNGHLYLEETYYSIGGGFVVTE
KELNVQGDGPEALHAEKEEAGFPHPFGSAVEMLAMGARTGKTIAQMKWENEAAFAPRGQVTTQLDAIWTAMDDCIDRGLR
MEGELPGGLMVKRRAKAIYDQLKAEAGTNQAQPHVANDWLSVYAMAVNEENAAGGRVVTSPTNGAAGVLPAVLRYYRDHC
IGATEDGLRDFMMTAAAIGGLIKHNASISGAEVGCQGEVGSASAMAAAGLCAALGGTNAQVENAAEIALEHHMGMTCDPV
AGLVQVPCIERNGLGAIKAVSAASLALRGDGTHFMPLDNCIEAMRQTGLDMNTKYKETSEGGLAVNLPQC

Sequences:

>Translated_470_residues
MFLSIFDIFKVGIGPSSSHTMGPMTAAARFLEDLRNGREKEPGAGELGGLGCSLHGSLAFTGKGHATDRAVILGFAGFEP
ATLDPDQAEALETEIRASGIVTPPGLPPLKFAPDADLIFDYDTTLPGHANGMILRAYDTNGHLYLEETYYSIGGGFVVTE
KELNVQGDGPEALHAEKEEAGFPHPFGSAVEMLAMGARTGKTIAQMKWENEAAFAPRGQVTTQLDAIWTAMDDCIDRGLR
MEGELPGGLMVKRRAKAIYDQLKAEAGTNQAQPHVANDWLSVYAMAVNEENAAGGRVVTSPTNGAAGVLPAVLRYYRDHC
IGATEDGLRDFMMTAAAIGGLIKHNASISGAEVGCQGEVGSASAMAAAGLCAALGGTNAQVENAAEIALEHHMGMTCDPV
AGLVQVPCIERNGLGAIKAVSAASLALRGDGTHFMPLDNCIEAMRQTGLDMNTKYKETSEGGLAVNLPQC
>Mature_470_residues
MFLSIFDIFKVGIGPSSSHTMGPMTAAARFLEDLRNGREKEPGAGELGGLGCSLHGSLAFTGKGHATDRAVILGFAGFEP
ATLDPDQAEALETEIRASGIVTPPGLPPLKFAPDADLIFDYDTTLPGHANGMILRAYDTNGHLYLEETYYSIGGGFVVTE
KELNVQGDGPEALHAEKEEAGFPHPFGSAVEMLAMGARTGKTIAQMKWENEAAFAPRGQVTTQLDAIWTAMDDCIDRGLR
MEGELPGGLMVKRRAKAIYDQLKAEAGTNQAQPHVANDWLSVYAMAVNEENAAGGRVVTSPTNGAAGVLPAVLRYYRDHC
IGATEDGLRDFMMTAAAIGGLIKHNASISGAEVGCQGEVGSASAMAAAGLCAALGGTNAQVENAAEIALEHHMGMTCDPV
AGLVQVPCIERNGLGAIKAVSAASLALRGDGTHFMPLDNCIEAMRQTGLDMNTKYKETSEGGLAVNLPQC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=472, Percent_Identity=47.4576271186441, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI48994925, Length=467, Percent_Identity=46.4668094218415, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1789161, Length=472, Percent_Identity=45.5508474576271, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49295; Mature: 49295

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSIFDIFKVGIGPSSSHTMGPMTAAARFLEDLRNGREKEPGAGELGGLGCSLHGSLAF
CEEEHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEEE
TGKGHATDRAVILGFAGFEPATLDPDQAEALETEIRASGIVTPPGLPPLKFAPDADLIFD
CCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
YDTTLPGHANGMILRAYDTNGHLYLEETYYSIGGGFVVTEKELNVQGDGPEALHAEKEEA
ECCCCCCCCCCEEEEEEECCCEEEEEEEEEECCCCEEEEECEEEECCCCCHHHCCCHHHC
GFPHPFGSAVEMLAMGARTGKTIAQMKWENEAAFAPRGQVTTQLDAIWTAMDDCIDRGLR
CCCCCCHHHHHHHHHCCCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCE
MEGELPGGLMVKRRAKAIYDQLKAEAGTNQAQPHVANDWLSVYAMAVNEENAAGGRVVTS
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEEC
PTNGAAGVLPAVLRYYRDHCIGATEDGLRDFMMTAAAIGGLIKHNASISGAEVGCQGEVG
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SASAMAAAGLCAALGGTNAQVENAAEIALEHHMGMTCDPVAGLVQVPCIERNGLGAIKAV
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHH
SAASLALRGDGTHFMPLDNCIEAMRQTGLDMNTKYKETSEGGLAVNLPQC
HHHEEEEECCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCC
>Mature Secondary Structure
MFLSIFDIFKVGIGPSSSHTMGPMTAAARFLEDLRNGREKEPGAGELGGLGCSLHGSLAF
CEEEHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEEE
TGKGHATDRAVILGFAGFEPATLDPDQAEALETEIRASGIVTPPGLPPLKFAPDADLIFD
CCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
YDTTLPGHANGMILRAYDTNGHLYLEETYYSIGGGFVVTEKELNVQGDGPEALHAEKEEA
ECCCCCCCCCCEEEEEEECCCEEEEEEEEEECCCCEEEEECEEEECCCCCHHHCCCHHHC
GFPHPFGSAVEMLAMGARTGKTIAQMKWENEAAFAPRGQVTTQLDAIWTAMDDCIDRGLR
CCCCCCHHHHHHHHHCCCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCE
MEGELPGGLMVKRRAKAIYDQLKAEAGTNQAQPHVANDWLSVYAMAVNEENAAGGRVVTS
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEEC
PTNGAAGVLPAVLRYYRDHCIGATEDGLRDFMMTAAAIGGLIKHNASISGAEVGCQGEVG
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SASAMAAAGLCAALGGTNAQVENAAEIALEHHMGMTCDPVAGLVQVPCIERNGLGAIKAV
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHHHH
SAASLALRGDGTHFMPLDNCIEAMRQTGLDMNTKYKETSEGGLAVNLPQC
HHHEEEEECCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]