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The map label for this gene is rnd [H]

Identifier: 89052719

GI number: 89052719

Start: 222405

End: 223016

Strand: Reverse

Name: rnd [H]

Synonym: Jann_0228

Alternate gene names: 89052719

Gene position: 223016-222405 (Counterclockwise)

Preceding gene: 89052728

Following gene: 89052718

Centisome position: 5.16

GC content: 57.68

Gene sequence:

>612_bases
ATGACCAACACTCTGTACCAAACCGACCTTCCCGATGACCTTGAACTCGGCCCTATCGTTGCGATTGATTGTGAGACGAT
GGGCCTCCATCCGCATCGCGACAGGCTTTGTGTGATCCAGCTGTCAGACGGCGATGGGAATGCACATCTGGTGCAGGTCG
CCAAAGGGCAGACGGCTGCGCCGAATCTCTGCGCGTTGCTGGAAGACCCTAACACCCTCAAATTGTTTCACTTCGGGCGG
TTTGACATCGCCGCGATGTACCATGCGTTTGGCGCGCTGACTGCGCCGGTCTATTGCACCAAGATCGCGTCCAAACTGGT
ACGGACCTATACGGATCGGCACGGGCTCAAGAACCTGCTTCAGGAACTTCTGGGCATCGACATCTCCAAGCAGCAGCAAT
CCTCTGATTGGGGGGCCGACAGCCTGACCGAGGCGCAGGTCGACTATGCGGCGTCCGACGTGCTGTATCTGCATGGCGTC
AAGGACAAGTTGGACGTGATGCTGGCCCGCGAAGGTCGCACCGAACTGGCGCAGGCGTGTTTTGACTTTCTGCCCATGCG
TGCGAAGCTGGATCTGGCCGGTTGGCCGGAAATGGACATTTTCAGTCATTAA

Upstream 100 bases:

>100_bases
CCTCTCCTGGGCACCAAGTCTTTCCTGCGCCACCGCCCCTTGGGCTACTTGAGCGCGAAGGCCTTCCCCTTCGAGACATA
TATTTTGAACGGGACGCCCG

Downstream 100 bases:

>100_bases
GGGACCCGTTCCGTGGCCCGTGATAACCTTTATTCCAAAGCTGTGATGTGGGTGAAAATCATCCTTCCCCTTGTGGCGCT
TGGACTTTTGTCATCGATCT

Product: 3'-5' exonuclease

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTNTLYQTDLPDDLELGPIVAIDCETMGLHPHRDRLCVIQLSDGDGNAHLVQVAKGQTAAPNLCALLEDPNTLKLFHFGR
FDIAAMYHAFGALTAPVYCTKIASKLVRTYTDRHGLKNLLQELLGIDISKQQQSSDWGADSLTEAQVDYAASDVLYLHGV
KDKLDVMLAREGRTELAQACFDFLPMRAKLDLAGWPEMDIFSH

Sequences:

>Translated_203_residues
MTNTLYQTDLPDDLELGPIVAIDCETMGLHPHRDRLCVIQLSDGDGNAHLVQVAKGQTAAPNLCALLEDPNTLKLFHFGR
FDIAAMYHAFGALTAPVYCTKIASKLVRTYTDRHGLKNLLQELLGIDISKQQQSSDWGADSLTEAQVDYAASDVLYLHGV
KDKLDVMLAREGRTELAQACFDFLPMRAKLDLAGWPEMDIFSH
>Mature_202_residues
TNTLYQTDLPDDLELGPIVAIDCETMGLHPHRDRLCVIQLSDGDGNAHLVQVAKGQTAAPNLCALLEDPNTLKLFHFGRF
DIAAMYHAFGALTAPVYCTKIASKLVRTYTDRHGLKNLLQELLGIDISKQQQSSDWGADSLTEAQVDYAASDVLYLHGVK
DKLDVMLAREGRTELAQACFDFLPMRAKLDLAGWPEMDIFSH

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=150, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 22489; Mature: 22358

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTLYQTDLPDDLELGPIVAIDCETMGLHPHRDRLCVIQLSDGDGNAHLVQVAKGQTAA
CCCCCCCCCCCCCCCCCCEEEEECEECCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCC
PNLCALLEDPNTLKLFHFGRFDIAAMYHAFGALTAPVYCTKIASKLVRTYTDRHGLKNLL
CCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QELLGIDISKQQQSSDWGADSLTEAQVDYAASDVLYLHGVKDKLDVMLAREGRTELAQAC
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHEEEECCCHHHHHHHH
FDFLPMRAKLDLAGWPEMDIFSH
HHHCCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TNTLYQTDLPDDLELGPIVAIDCETMGLHPHRDRLCVIQLSDGDGNAHLVQVAKGQTAA
CCCCCCCCCCCCCCCCCEEEEECEECCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCC
PNLCALLEDPNTLKLFHFGRFDIAAMYHAFGALTAPVYCTKIASKLVRTYTDRHGLKNLL
CCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QELLGIDISKQQQSSDWGADSLTEAQVDYAASDVLYLHGVKDKLDVMLAREGRTELAQAC
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHEEEECCCHHHHHHHH
FDFLPMRAKLDLAGWPEMDIFSH
HHHCCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]