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The map label for this gene is kdsB [H]

Identifier: 89052707

GI number: 89052707

Start: 210834

End: 211631

Strand: Direct

Name: kdsB [H]

Synonym: Jann_0216

Alternate gene names: 89052707

Gene position: 210834-211631 (Clockwise)

Preceding gene: 89052706

Following gene: 89052708

Centisome position: 4.88

GC content: 63.91

Gene sequence:

>798_bases
GTGAGCGTTGCTTGCGTCATCCCGGCCCGCTATGCGTCTGCCCGCTTTCCCGGCAAACCGCTTGCTATGCTGACGGGCGC
AACCGGTGAGAAAGTGTCCCTGATCGAGCGGTCCTGGCGGGCGGCGCAGAATGTCTCGGGCCTCGACGCGGTCTATGTCG
CAACCGATGATGAGCGTATCGCCGATGCCGCGCGCGAGTTTGGCGCGGAGGTTCTGATGACCTCCTCGGAGGCCCGCAAT
GGGACGGAGCGGTGCGCCGAGGCACTAGAAATCCTTGGCGATGTGGAGATGGTCGTGAACCTGCAAGGCGACGCGCCGCT
GACGCCGCCCTGGTTCCTGGAACAGCTTGTCGACGGCCTCCGCAATGATGCCCAAGCCGCGATCGCAACGCCCATTTTGC
GGTGTGATGGGGAGACATTGGCCGCGTTGAAAGCTGACCGCGCCGCTGGCCGTGTGGGGGGGACAACGGCGGTGGCCGAC
AGCAAGATGCGCGGGCTGTATTTTTCCAAGGAAGTGGTGCCGTTCACGTCTGAAACCTACGCCCCCGATGCGCCAACGCC
GGTGTTCCATCACGTCGGCGTCTACGCCTACCGCCCCTGGGCTTTGCGCGCGTACCCCCATTGGTCCATCGGCCCGCTGG
AGATGCTGGAAGGTCTGGAGCAATTGCGGTTTCTGGAGGCCGGACACCCCGTCTTATGCGTTGAGGTGGAGGCCCATGGC
GCAAAGTTCTGGGAATTGAACAACCCCGAAGATATCCCCCGGATCGAGGCCATGCTGCGAGACATGGGCGCGCCTTGA

Upstream 100 bases:

>100_bases
TGGTCCGGTTTGAGGATCATGCGCCGTTTGAATACGGCAAGGACGGGTTCGCCAACGGCTTCTTCATTGCCTACGCCCCG
GGTCTGGAATTGCAGCTGCC

Downstream 100 bases:

>100_bases
GCGCGCTCCGCCTCAGTGTTGTCGTCGTCAGCGTTGGGCGGCCAGAGGCCCTGCGTCGGTGTCTGATCAGCCTGTCGCAG
CAGGCCAAGGCCGGATGTGA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSVACVIPARYASARFPGKPLAMLTGATGEKVSLIERSWRAAQNVSGLDAVYVATDDERIADAAREFGAEVLMTSSEARN
GTERCAEALEILGDVEMVVNLQGDAPLTPPWFLEQLVDGLRNDAQAAIATPILRCDGETLAALKADRAAGRVGGTTAVAD
SKMRGLYFSKEVVPFTSETYAPDAPTPVFHHVGVYAYRPWALRAYPHWSIGPLEMLEGLEQLRFLEAGHPVLCVEVEAHG
AKFWELNNPEDIPRIEAMLRDMGAP

Sequences:

>Translated_265_residues
MSVACVIPARYASARFPGKPLAMLTGATGEKVSLIERSWRAAQNVSGLDAVYVATDDERIADAAREFGAEVLMTSSEARN
GTERCAEALEILGDVEMVVNLQGDAPLTPPWFLEQLVDGLRNDAQAAIATPILRCDGETLAALKADRAAGRVGGTTAVAD
SKMRGLYFSKEVVPFTSETYAPDAPTPVFHHVGVYAYRPWALRAYPHWSIGPLEMLEGLEQLRFLEAGHPVLCVEVEAHG
AKFWELNNPEDIPRIEAMLRDMGAP
>Mature_264_residues
SVACVIPARYASARFPGKPLAMLTGATGEKVSLIERSWRAAQNVSGLDAVYVATDDERIADAAREFGAEVLMTSSEARNG
TERCAEALEILGDVEMVVNLQGDAPLTPPWFLEQLVDGLRNDAQAAIATPILRCDGETLAALKADRAAGRVGGTTAVADS
KMRGLYFSKEVVPFTSETYAPDAPTPVFHHVGVYAYRPWALRAYPHWSIGPLEMLEGLEQLRFLEAGHPVLCVEVEAHGA
KFWELNNPEDIPRIEAMLRDMGAP

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=270, Percent_Identity=35.1851851851852, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28766; Mature: 28635

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVACVIPARYASARFPGKPLAMLTGATGEKVSLIERSWRAAQNVSGLDAVYVATDDERI
CCEEEEECCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHH
ADAAREFGAEVLMTSSEARNGTERCAEALEILGDVEMVVNLQGDAPLTPPWFLEQLVDGL
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHH
RNDAQAAIATPILRCDGETLAALKADRAAGRVGGTTAVADSKMRGLYFSKEVVPFTSETY
HCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHCCHHCCEEECCCCCCCCCCCC
APDAPTPVFHHVGVYAYRPWALRAYPHWSIGPLEMLEGLEQLRFLEAGHPVLCVEVEAHG
CCCCCCCHHHHCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
AKFWELNNPEDIPRIEAMLRDMGAP
CEEEECCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SVACVIPARYASARFPGKPLAMLTGATGEKVSLIERSWRAAQNVSGLDAVYVATDDERI
CEEEEECCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHH
ADAAREFGAEVLMTSSEARNGTERCAEALEILGDVEMVVNLQGDAPLTPPWFLEQLVDGL
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHH
RNDAQAAIATPILRCDGETLAALKADRAAGRVGGTTAVADSKMRGLYFSKEVVPFTSETY
HCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHCCHHCCEEECCCCCCCCCCCC
APDAPTPVFHHVGVYAYRPWALRAYPHWSIGPLEMLEGLEQLRFLEAGHPVLCVEVEAHG
CCCCCCCHHHHCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
AKFWELNNPEDIPRIEAMLRDMGAP
CEEEECCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA