Click here to switch to the map view.

The map label for this gene is cysQ [H]

Identifier: 89052706

GI number: 89052706

Start: 210040

End: 210837

Strand: Direct

Name: cysQ [H]

Synonym: Jann_0215

Alternate gene names: 89052706

Gene position: 210040-210837 (Clockwise)

Preceding gene: 89052704

Following gene: 89052707

Centisome position: 4.86

GC content: 60.53

Gene sequence:

>798_bases
ATGGATCACGAGAAAATTGTTGCCGTCATGCGTACCGCTGCCCTGGAGGCCGGCGACGCGATCATGGAGGTTTATGGCGC
GGAGGATTTCGACGTGAAGGTGAAATCCGACGATAGCCCTGTGACAGAGGCGGATGAGGCGGCGGATGCCATCATTTCCC
GGCACCTGCGCGCGGCGTTTCCGGACGTGACGTTGATCACCGAAGAACAGGCCGACAGCCATGGGCTGAGCGCGGATCAG
TTCCTGATCGTGGACCCGTTGGACGGCACCAAAGAGTTCATCAAGCGGCGCGGCGATTTCACGGTGAACATCGCCTTGGT
GGAACATGGCGTACCTGTGCGTGGCATCGTTTATGCGCCCGCGAAGGGGCGTCTGTTTTACACAAATGCCGACGGAGTGA
GCATTGAGGAGGCAGGCCCGTTCGAGCCGAATGCGCCTGGCAGGCTCGATCCAATCACAGTGTCACGCCCGGATAACAGC
GCGTTGCGCGTCGTGGCGTCGAAGTCGCACCGGGATCAGGCAACAGACCACTACATCAACAAATACGACCACGCGGATAT
GAAAAGCGCAGGGTCATCGCTGAAGTTCTGCCTTGTCGCGACGGGGGAGGCGGATTTGTACCCCCGCCTTGGCCGCACGA
TGGAATGGGATACCGCGGCAGGCGATGCCGTGTTGCGCGGGGCCGGTGGCAAGATGGTCCGGTTTGAGGATCATGCGCCG
TTTGAATACGGCAAGGACGGGTTCGCCAACGGCTTCTTCATTGCCTACGCCCCGGGTCTGGAATTGCAGCTGCCGTGA

Upstream 100 bases:

>100_bases
GCTTGTTTTGCGCGCCGCCCGCAGGCCTTGCTTGCAGTTCTCACGTGGACCGAGGATAACGCGGTAAGTGTTAATTTTCA
ATTCAACCGTGGGTGAGCCT

Downstream 100 bases:

>100_bases
GCGTTGCTTGCGTCATCCCGGCCCGCTATGCGTCTGCCCGCTTTCCCGGCAAACCGCTTGCTATGCTGACGGGCGCAACC
GGTGAGAAAGTGTCCCTGAT

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MDHEKIVAVMRTAALEAGDAIMEVYGAEDFDVKVKSDDSPVTEADEAADAIISRHLRAAFPDVTLITEEQADSHGLSADQ
FLIVDPLDGTKEFIKRRGDFTVNIALVEHGVPVRGIVYAPAKGRLFYTNADGVSIEEAGPFEPNAPGRLDPITVSRPDNS
ALRVVASKSHRDQATDHYINKYDHADMKSAGSSLKFCLVATGEADLYPRLGRTMEWDTAAGDAVLRGAGGKMVRFEDHAP
FEYGKDGFANGFFIAYAPGLELQLP

Sequences:

>Translated_265_residues
MDHEKIVAVMRTAALEAGDAIMEVYGAEDFDVKVKSDDSPVTEADEAADAIISRHLRAAFPDVTLITEEQADSHGLSADQ
FLIVDPLDGTKEFIKRRGDFTVNIALVEHGVPVRGIVYAPAKGRLFYTNADGVSIEEAGPFEPNAPGRLDPITVSRPDNS
ALRVVASKSHRDQATDHYINKYDHADMKSAGSSLKFCLVATGEADLYPRLGRTMEWDTAAGDAVLRGAGGKMVRFEDHAP
FEYGKDGFANGFFIAYAPGLELQLP
>Mature_265_residues
MDHEKIVAVMRTAALEAGDAIMEVYGAEDFDVKVKSDDSPVTEADEAADAIISRHLRAAFPDVTLITEEQADSHGLSADQ
FLIVDPLDGTKEFIKRRGDFTVNIALVEHGVPVRGIVYAPAKGRLFYTNADGVSIEEAGPFEPNAPGRLDPITVSRPDNS
ALRVVASKSHRDQATDHYINKYDHADMKSAGSSLKFCLVATGEADLYPRLGRTMEWDTAAGDAVLRGAGGKMVRFEDHAP
FEYGKDGFANGFFIAYAPGLELQLP

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=210, Percent_Identity=47.1428571428571, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1788882, Length=231, Percent_Identity=32.9004329004329, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71995897, Length=169, Percent_Identity=31.9526627218935, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71995905, Length=169, Percent_Identity=31.9526627218935, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320493, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357957, Length=241, Percent_Identity=26.5560165975104, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641722, Length=233, Percent_Identity=24.8927038626609, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24664922, Length=229, Percent_Identity=27.9475982532751, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 28743; Mature: 28743

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHEKIVAVMRTAALEAGDAIMEVYGAEDFDVKVKSDDSPVTEADEAADAIISRHLRAAF
CCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
PDVTLITEEQADSHGLSADQFLIVDPLDGTKEFIKRRGDFTVNIALVEHGVPVRGIVYAP
CCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEEEEEEECCCCEEEEEECC
AKGRLFYTNADGVSIEEAGPFEPNAPGRLDPITVSRPDNSALRVVASKSHRDQATDHYIN
CCCEEEEECCCCCEECCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHH
KYDHADMKSAGSSLKFCLVATGEADLYPRLGRTMEWDTAAGDAVLRGAGGKMVRFEDHAP
HCCCCHHHHCCCCEEEEEEECCCCCCCHHHCCEEECCCCCCCEEEECCCCCEEEEECCCC
FEYGKDGFANGFFIAYAPGLELQLP
CCCCCCCCCCCEEEEEECCEEEECC
>Mature Secondary Structure
MDHEKIVAVMRTAALEAGDAIMEVYGAEDFDVKVKSDDSPVTEADEAADAIISRHLRAAF
CCHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
PDVTLITEEQADSHGLSADQFLIVDPLDGTKEFIKRRGDFTVNIALVEHGVPVRGIVYAP
CCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEEEEEEECCCCEEEEEECC
AKGRLFYTNADGVSIEEAGPFEPNAPGRLDPITVSRPDNSALRVVASKSHRDQATDHYIN
CCCEEEEECCCCCEECCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHH
KYDHADMKSAGSSLKFCLVATGEADLYPRLGRTMEWDTAAGDAVLRGAGGKMVRFEDHAP
HCCCCHHHHCCCCEEEEEEECCCCCCCHHHCCEEECCCCCCCEEEECCCCCEEEEECCCC
FEYGKDGFANGFFIAYAPGLELQLP
CCCCCCCCCCCEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]