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The map label for this gene is coaE

Identifier: 89052686

GI number: 89052686

Start: 186433

End: 187017

Strand: Reverse

Name: coaE

Synonym: Jann_0195

Alternate gene names: 89052686

Gene position: 187017-186433 (Counterclockwise)

Preceding gene: 89052687

Following gene: 89052685

Centisome position: 4.33

GC content: 58.63

Gene sequence:

>585_bases
ATGAGTTTTGCTCTCGGTCTCACGGGCTCCATCGGGATGGGTAAAAGCACGACAGCCGCGATGTTTCGTGACCTTGATGT
GCCGGTATGGGACGCTGATGCCACCGTTCACAAGCTCTATGCTAGGGGCGGTGCCGCCGTCGCGCCAATCGACGCTCTCG
TTCCCGGTGCGATGAAAGACGGGGCCATTGACCGGGCGGTTTTGCGCGCGGCCATCGCAGACGATGCCTCCCTCCTCAAA
CAGATTGAGGCCATCGTTCACCCCCTTGTGGCCAAGGATCGCGCGATGTTTCGCGACATTCATTCCACCGCCCCGCTCAT
CATTTTGGATATTCCGTTACTTTTTGAAACCGGTGGAGATGCGGCCTGTGACGCCACGCTGGTTGTAACGACATCGCCTG
AGGAACAACGCCGTCGTGTCCTCGCTCGCGGTACGTCCGAAGACACACTGCATGACCTGCTCTCGCGGCAGATGCCGGAT
GCCGAGAAGCGTGCCCGCGCAACATATGTTATTGAGACGGATACGCTGGACGGCACCCGGCAAGACGTGGCACATCTGGT
ATCAAAGTTGACTGAAGGCACATGA

Upstream 100 bases:

>100_bases
GCCTCGGTATGCTGCTTCATCAAGCGGTTCCCGGGTTTGAGCGATGGTTCAATTACACGCCGACCGTTGATGAGGACCTT
CGCGAAGCTGTGCTGGCCGG

Downstream 100 bases:

>100_bases
TGAATGCGTGAAATCGTCCTCGATACTGAAACGACCGGTCTTAACCCCTACGACATGCCGCGCCACCGTATCGTGGAGAT
CGGTGCCGTAGAGATTTTCA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSFALGLTGSIGMGKSTTAAMFRDLDVPVWDADATVHKLYARGGAAVAPIDALVPGAMKDGAIDRAVLRAAIADDASLLK
QIEAIVHPLVAKDRAMFRDIHSTAPLIILDIPLLFETGGDAACDATLVVTTSPEEQRRRVLARGTSEDTLHDLLSRQMPD
AEKRARATYVIETDTLDGTRQDVAHLVSKLTEGT

Sequences:

>Translated_194_residues
MSFALGLTGSIGMGKSTTAAMFRDLDVPVWDADATVHKLYARGGAAVAPIDALVPGAMKDGAIDRAVLRAAIADDASLLK
QIEAIVHPLVAKDRAMFRDIHSTAPLIILDIPLLFETGGDAACDATLVVTTSPEEQRRRVLARGTSEDTLHDLLSRQMPD
AEKRARATYVIETDTLDGTRQDVAHLVSKLTEGT
>Mature_193_residues
SFALGLTGSIGMGKSTTAAMFRDLDVPVWDADATVHKLYARGGAAVAPIDALVPGAMKDGAIDRAVLRAAIADDASLLKQ
IEAIVHPLVAKDRAMFRDIHSTAPLIILDIPLLFETGGDAACDATLVVTTSPEEQRRRVLARGTSEDTLHDLLSRQMPDA
EKRARATYVIETDTLDGTRQDVAHLVSKLTEGT

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI110227607, Length=176, Percent_Identity=29.5454545454545, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1786292, Length=190, Percent_Identity=30.5263157894737, Blast_Score=70, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17554944, Length=201, Percent_Identity=27.8606965174129, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=201, Percent_Identity=29.8507462686567, Blast_Score=82, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644728, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_JANSC (Q28W00)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508137.1
- ProteinModelPortal:   Q28W00
- SMR:   Q28W00
- STRING:   Q28W00
- GeneID:   3932632
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0195
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   HEFELIS
- BioCyc:   JSP290400:JANN_0195-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 20718; Mature: 20587

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS51219 DPCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFALGLTGSIGMGKSTTAAMFRDLDVPVWDADATVHKLYARGGAAVAPIDALVPGAMKD
CCEECCCCCCCCCCCCHHHHHHHHCCCCEECCCHHHHHHHHCCCCCCCCHHHHCCCCCCC
GAIDRAVLRAAIADDASLLKQIEAIVHPLVAKDRAMFRDIHSTAPLIILDIPLLFETGGD
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCC
AACDATLVVTTSPEEQRRRVLARGTSEDTLHDLLSRQMPDAEKRARATYVIETDTLDGTR
CCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCH
QDVAHLVSKLTEGT
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SFALGLTGSIGMGKSTTAAMFRDLDVPVWDADATVHKLYARGGAAVAPIDALVPGAMKD
CEECCCCCCCCCCCCHHHHHHHHCCCCEECCCHHHHHHHHCCCCCCCCHHHHCCCCCCC
GAIDRAVLRAAIADDASLLKQIEAIVHPLVAKDRAMFRDIHSTAPLIILDIPLLFETGGD
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCC
AACDATLVVTTSPEEQRRRVLARGTSEDTLHDLLSRQMPDAEKRARATYVIETDTLDGTR
CCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCH
QDVAHLVSKLTEGT
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA