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The map label for this gene is hslV

Identifier: 89052676

GI number: 89052676

Start: 178141

End: 178698

Strand: Direct

Name: hslV

Synonym: Jann_0185

Alternate gene names: 89052676

Gene position: 178141-178698 (Clockwise)

Preceding gene: 89052675

Following gene: 89052677

Centisome position: 4.13

GC content: 59.5

Gene sequence:

>558_bases
ATGGCGAAAGAAGAATTCCCCGGTTGGCACGGCACAACAATCATCGGTGTGCGTAAGGGCGGCAAGGTCGTTGTGGCTGG
TGATGGGCAAGTCAGTCTTGGGCCGACTGTGATCAAAGGCTCCGCCCGGAAGGTGCGGCGACTGTCGCCCGGTGGCTATG
ATGTGGTGTGCGGATTTGCGGGCTCCACCGCGGACGCCTTCACGCTACTGGAACGGCTTGAGGCCAAGCTGGAAGCCACG
CCCGGACAATTGCAGCGGGCAAGCGTGGAGCTGGCCAAGGACTGGCGGACAGACAAATATCTGCAAAAGCTGGAAGCGAT
GCTGATCGTCACCGATGGCAGTGAGCTTTATATCATCACCGGTGCGGGCGACGTGCTGGAACCGGAACACGACATTGCGG
CGATCGGATCGGGCGGAAACTTCGCCTTGGCTGCCGCGCGCGGTATGATGGACAGTGACAAGGATGCCGAAGCCGTCGCC
CGGGATGCCATGGCGATTGCCTCGGATATTTGCGTCTATACCAACGGCAATCTTACTGTTGAGACGATCTCTGCATGA

Upstream 100 bases:

>100_bases
GCTGGCCATGCGCGTGCCGCGCCGCAAAGGTTGGCCCGGCACGTAGCTTGTCGCCAGCGTCCGGGCTGTCCATATAGACG
TGGAACGGATGGAGGCCCTG

Downstream 100 bases:

>100_bases
GTGACGTCACCCGCGATGACCTGCGCGCCGCAATAGGCGCTGGCCTGATGACGGAGGCGCAGGCAGCCTCCCTCATTTCG
CTGGCGGAAGAACGGGAAGG

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MAKEEFPGWHGTTIIGVRKGGKVVVAGDGQVSLGPTVIKGSARKVRRLSPGGYDVVCGFAGSTADAFTLLERLEAKLEAT
PGQLQRASVELAKDWRTDKYLQKLEAMLIVTDGSELYIITGAGDVLEPEHDIAAIGSGGNFALAAARGMMDSDKDAEAVA
RDAMAIASDICVYTNGNLTVETISA

Sequences:

>Translated_185_residues
MAKEEFPGWHGTTIIGVRKGGKVVVAGDGQVSLGPTVIKGSARKVRRLSPGGYDVVCGFAGSTADAFTLLERLEAKLEAT
PGQLQRASVELAKDWRTDKYLQKLEAMLIVTDGSELYIITGAGDVLEPEHDIAAIGSGGNFALAAARGMMDSDKDAEAVA
RDAMAIASDICVYTNGNLTVETISA
>Mature_184_residues
AKEEFPGWHGTTIIGVRKGGKVVVAGDGQVSLGPTVIKGSARKVRRLSPGGYDVVCGFAGSTADAFTLLERLEAKLEATP
GQLQRASVELAKDWRTDKYLQKLEAMLIVTDGSELYIITGAGDVLEPEHDIAAIGSGGNFALAAARGMMDSDKDAEAVAR
DAMAIASDICVYTNGNLTVETISA

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=174, Percent_Identity=55.7471264367816, Blast_Score=187, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_JANSC (Q28W10)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508127.1
- ProteinModelPortal:   Q28W10
- SMR:   Q28W10
- STRING:   Q28W10
- MEROPS:   T01.006
- GeneID:   3932622
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0185
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   Q28W10
- ProtClustDB:   PRK05456
- BioCyc:   JSP290400:JANN_0185-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19387; Mature: 19256

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: ACT_SITE 12-12

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEEFPGWHGTTIIGVRKGGKVVVAGDGQVSLGPTVIKGSARKVRRLSPGGYDVVCGFA
CCCCCCCCCCCEEEEEEECCCEEEEECCCCEEECCEEEECCCHHHHCCCCCCEEEEEECC
GSTADAFTLLERLEAKLEATPGQLQRASVELAKDWRTDKYLQKLEAMLIVTDGSELYIIT
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHEEEEEEECCCEEEEEE
GAGDVLEPEHDIAAIGSGGNFALAAARGMMDSDKDAEAVARDAMAIASDICVYTNGNLTV
CCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEECCCEEE
ETISA
EEECC
>Mature Secondary Structure 
AKEEFPGWHGTTIIGVRKGGKVVVAGDGQVSLGPTVIKGSARKVRRLSPGGYDVVCGFA
CCCCCCCCCCEEEEEEECCCEEEEECCCCEEECCEEEECCCHHHHCCCCCCEEEEEECC
GSTADAFTLLERLEAKLEATPGQLQRASVELAKDWRTDKYLQKLEAMLIVTDGSELYIIT
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHEEEEEEECCCEEEEEE
GAGDVLEPEHDIAAIGSGGNFALAAARGMMDSDKDAEAVARDAMAIASDICVYTNGNLTV
CCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEECCCEEE
ETISA
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA