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The map label for this gene is carA [H]

Identifier: 161898396

GI number: 161898396

Start: 1201626

End: 1202780

Strand: Reverse

Name: carA [H]

Synonym: Jann_1246

Alternate gene names: 161898396

Gene position: 1202780-1201626 (Counterclockwise)

Preceding gene: 89053739

Following gene: 89053736

Centisome position: 27.86

GC content: 64.16

Gene sequence:

>1155_bases
ATGTCTGATCACCCCACCGCCTGCCTTGCCCTCGCCGATGGCACCATCTTCTACGGCAAAGGGTTTGGGGCCACCGGCAT
GCGCGTGGCGGAACTGTGCTTCAACACCGCCATGACCGGCTATCAGGAGATCATGACCGACCCGTCCTACGCGGGGCAGA
TCGTGACCTTCACCTTCCCCCATATCGGCAATACCGGGACGAATGTGGACGATGACGAAACCGCCGATCCCGTGGCCGAG
GGAATGGTGGTGAAGTGGGACGTGACCGAGCCGTCGAACTGGCGCGCGCAATCGCATCTGGTAGATTGGCTGGCGCGCAC
GGGACGCGTCGGCATCGGCGGCGTCGACACACGGCGGCTGACGCGTGAGATCCGGCAACAGGGCGCACCGCATGTGGCCC
TGGCCCATGATCCGGACGGTAACTTTGATATCGAGGCGATGGTCAAGGCCGCCCGGGATTTCGCCGGTCTGGAAGGCGTT
GATCTGGCCAAGGACGTCACCTGCGCGCAATCCTACCGCTGGGATGAGATGCGGTGGGCCTGGCCCGAGGGCTACACCAA
GCGGACAGGTCCCGCCCCCAAGGTTGTCGCGCTGGATTACGGTGCGAAACGCAACATCCTGCGCTGCCTGGCGAGCGCTG
GTATGGACGTCACCGTGATGCCCGCCACCACGACAGCGGAGGAGGTTCTGGCCCAATCCCCCGACGGCGTCTTCCTGTCC
AACGGCCCCGGCGACCCGGCGGCCACGGGCGCATATGCCGTCCCGATGATCAAGGGCGTCTTGGAAGCGGACATGCCCGT
CTTCGGGATTTGCCTTGGCCACCAGATGCTGGCCCTCGCACTTGGCGCCAAGACCGTGAAGATGAACCACGGCCACCACG
GCGCGAACCATCCTGTGAAGGAGATCGGCACCGGCAAGGTGGAAATCACGTCGATGAACCACGGCTTCACGGTCGACAGC
CAAAGCCTGCCCGAGGGCGTGTCCGAGACCCATGTAAGCCTTTTTGACGGCTCGAACTGTGGCATCGCGGTGGAGGGAAA
ACCGATCTTCTCGGTCCAGCATCACCCGGAGGCCAGCCCCGGCCCGCAAGACAGCTTCTACCTGTTCGAGCGCTTTGCCG
ACGCCGTCACGGCGCGCACCAAAACGAAAGCGTAA

Upstream 100 bases:

>100_bases
CCGCCGCAACAAGGTGCACCTTGACCGCATGGTCTGGCCCCCATACACCACCAAAAGTTTGCCCGCGCCCTTGCCTCGCC
GCCCTATTCGGAGCACGCCC

Downstream 100 bases:

>100_bases
CCACATTCGATCGCATTATTTGCTTTCGGTTTACGAATTCTTAACCAATTCCACAGGACAAACGGGTTGGCGTAACAGGC
GCCAGCATTAAGGAATTTGG

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSDHPTACLALADGTIFYGKGFGATGMRVAELCFNTAMTGYQEIMTDPSYAGQIVTFTFPHIGNTGTNVDDDETADPVAE
GMVVKWDVTEPSNWRAQSHLVDWLARTGRVGIGGVDTRRLTREIRQQGAPHVALAHDPDGNFDIEAMVKAARDFAGLEGV
DLAKDVTCAQSYRWDEMRWAWPEGYTKRTGPAPKVVALDYGAKRNILRCLASAGMDVTVMPATTTAEEVLAQSPDGVFLS
NGPGDPAATGAYAVPMIKGVLEADMPVFGICLGHQMLALALGAKTVKMNHGHHGANHPVKEIGTGKVEITSMNHGFTVDS
QSLPEGVSETHVSLFDGSNCGIAVEGKPIFSVQHHPEASPGPQDSFYLFERFADAVTARTKTKA

Sequences:

>Translated_384_residues
MSDHPTACLALADGTIFYGKGFGATGMRVAELCFNTAMTGYQEIMTDPSYAGQIVTFTFPHIGNTGTNVDDDETADPVAE
GMVVKWDVTEPSNWRAQSHLVDWLARTGRVGIGGVDTRRLTREIRQQGAPHVALAHDPDGNFDIEAMVKAARDFAGLEGV
DLAKDVTCAQSYRWDEMRWAWPEGYTKRTGPAPKVVALDYGAKRNILRCLASAGMDVTVMPATTTAEEVLAQSPDGVFLS
NGPGDPAATGAYAVPMIKGVLEADMPVFGICLGHQMLALALGAKTVKMNHGHHGANHPVKEIGTGKVEITSMNHGFTVDS
QSLPEGVSETHVSLFDGSNCGIAVEGKPIFSVQHHPEASPGPQDSFYLFERFADAVTARTKTKA
>Mature_383_residues
SDHPTACLALADGTIFYGKGFGATGMRVAELCFNTAMTGYQEIMTDPSYAGQIVTFTFPHIGNTGTNVDDDETADPVAEG
MVVKWDVTEPSNWRAQSHLVDWLARTGRVGIGGVDTRRLTREIRQQGAPHVALAHDPDGNFDIEAMVKAARDFAGLEGVD
LAKDVTCAQSYRWDEMRWAWPEGYTKRTGPAPKVVALDYGAKRNILRCLASAGMDVTVMPATTTAEEVLAQSPDGVFLSN
GPGDPAATGAYAVPMIKGVLEADMPVFGICLGHQMLALALGAKTVKMNHGHHGANHPVKEIGTGKVEITSMNHGFTVDSQ
SLPEGVSETHVSLFDGSNCGIAVEGKPIFSVQHHPEASPGPQDSFYLFERFADAVTARTKTKA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=384, Percent_Identity=38.0208333333333, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI169790915, Length=382, Percent_Identity=34.8167539267016, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI21361331, Length=382, Percent_Identity=34.8167539267016, Blast_Score=184, Evalue=8e-47,
Organism=Escherichia coli, GI1786215, Length=382, Percent_Identity=51.3089005235602, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI193204318, Length=384, Percent_Identity=35.6770833333333, Blast_Score=224, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6324878, Length=388, Percent_Identity=37.3711340206186, Blast_Score=218, Evalue=9e-58,
Organism=Saccharomyces cerevisiae, GI6322331, Length=391, Percent_Identity=37.3401534526854, Blast_Score=217, Evalue=3e-57,
Organism=Drosophila melanogaster, GI45555749, Length=396, Percent_Identity=37.6262626262626, Blast_Score=237, Evalue=8e-63,
Organism=Drosophila melanogaster, GI24642586, Length=396, Percent_Identity=37.6262626262626, Blast_Score=237, Evalue=8e-63,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41092; Mature: 40960

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDHPTACLALADGTIFYGKGFGATGMRVAELCFNTAMTGYQEIMTDPSYAGQIVTFTFP
CCCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
HIGNTGTNVDDDETADPVAEGMVVKWDVTEPSNWRAQSHLVDWLARTGRVGIGGVDTRRL
CCCCCCCCCCCCCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
TREIRQQGAPHVALAHDPDGNFDIEAMVKAARDFAGLEGVDLAKDVTCAQSYRWDEMRWA
HHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEE
WPEGYTKRTGPAPKVVALDYGAKRNILRCLASAGMDVTVMPATTTAEEVLAQSPDGVFLS
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCEEEE
NGPGDPAATGAYAVPMIKGVLEADMPVFGICLGHQMLALALGAKTVKMNHGHHGANHPVK
CCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHH
EIGTGKVEITSMNHGFTVDSQSLPEGVSETHVSLFDGSNCGIAVEGKPIFSVQHHPEASP
HHCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEECCCCCEEECCCEEEEEECCCCCCC
GPQDSFYLFERFADAVTARTKTKA
CCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDHPTACLALADGTIFYGKGFGATGMRVAELCFNTAMTGYQEIMTDPSYAGQIVTFTFP
CCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
HIGNTGTNVDDDETADPVAEGMVVKWDVTEPSNWRAQSHLVDWLARTGRVGIGGVDTRRL
CCCCCCCCCCCCCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
TREIRQQGAPHVALAHDPDGNFDIEAMVKAARDFAGLEGVDLAKDVTCAQSYRWDEMRWA
HHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEE
WPEGYTKRTGPAPKVVALDYGAKRNILRCLASAGMDVTVMPATTTAEEVLAQSPDGVFLS
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCEEEE
NGPGDPAATGAYAVPMIKGVLEADMPVFGICLGHQMLALALGAKTVKMNHGHHGANHPVK
CCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHH
EIGTGKVEITSMNHGFTVDSQSLPEGVSETHVSLFDGSNCGIAVEGKPIFSVQHHPEASP
HHCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEECCCCCEEECCCEEEEEECCCCCCC
GPQDSFYLFERFADAVTARTKTKA
CCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA