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The map label for this gene is ctaA

Identifier: 88658524

GI number: 88658524

Start: 279343

End: 280377

Strand: Direct

Name: ctaA

Synonym: ECH_0294

Alternate gene names: 88658524

Gene position: 279343-280377 (Clockwise)

Preceding gene: 88657598

Following gene: 88658217

Centisome position: 23.75

GC content: 27.25

Gene sequence:

>1035_bases
ATGAAAATTGCTAGTGATAATAGAGAAGTATGTGTTGGTGTGAAAATTTGGTTATGTATATGTTGTATAGGGATATTGCT
TATGGTGTTAGTTGGAGGGATAACACGTCTTACTCATTCTGGTTTGTCGATTACTGAATGGAATCCTGTTATTGGAGTAT
TTCCTCCAATTGGAGAAAGAGCATGGATTAGAGAAAAAATAAAGTACATGGCTACTCCAGAATTTAAATATCTAAATTTT
AATATTACACTTCGGGGATTTAGGAAGTTATATTTGATAGAGTATTTTCATCGATTACTTGGGAGAATTGTTGGACTAAC
ATTTTTAATTCCGTTTTTATATTTTACATATAAAAAAAAACTACATAGAAATTTGATAATAAATTTCATAGTTATTTGTT
TGTTAATACTGTTTCAGGGAGTTGTAGGATGGTTTATGGTAAAAAGCGGCTTAATTGATCGTCCTCATGTAAGTCACTAT
AAATTAACAGCTCATTTATTGTTAGCATTGTTGATTTTCTATCTTTTGTGGAGACAATTTTTATTATCTACTATTTCTAA
AGTAACTTATAACATTAAAGTCAATGGAACATTAATTTTTTCTGTAATTAGTGTATTAATTGTTACTCAAATAACATTTG
GTTCATTAGTTGCTGGATTAAATGCTGGATTGTTGGATAAAACTATTCCTTTTTTAGCAGGAAAATTAATGTTAGAAGAT
TTGTTATTCATAAAGCCATTGTGGTATAATATTTTTGAGAATCCTGTTACGGTACAATTTATACATGAGCTAATAGCAAC
TCTTATTTTCTTAGTAGTTATTATAACTTTGTTAATATTAAGATTGAATCTTTTTCCAGCATATTTACTATTAATATGTT
TGTGTCTTCAATTAACATTAGGAGTACTAACATTTATATATAATGTTCCTATAGTTCTTGCTTCTTTACATCAAGTAACA
GCTTTTATTTTATTTGCTGTTAATACTTACTTGTTACATTATATGAAATTATCTAAGTTACAATATGTTAAATAG

Upstream 100 bases:

>100_bases
TACGTCATAATGCTATAAATTTTTGTGTAAATTTACATAATTCTATAAGGAAGAGTCTCATTTTTGTTTATAATGTTGAA
GATATATTCATAGGTTTATG

Downstream 100 bases:

>100_bases
GAGGTTTGTGTGCTTGATAGATGATACAAGGAATGCTTGTAATTTCATATCTTTGAATTAAGTAAGTTGTTATATATGTT
ATAAGTTAGTTTTGTACTTT

Product: putative cytochrome oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKIASDNREVCVGVKIWLCICCIGILLMVLVGGITRLTHSGLSITEWNPVIGVFPPIGERAWIREKIKYMATPEFKYLNF
NITLRGFRKLYLIEYFHRLLGRIVGLTFLIPFLYFTYKKKLHRNLIINFIVICLLILFQGVVGWFMVKSGLIDRPHVSHY
KLTAHLLLALLIFYLLWRQFLLSTISKVTYNIKVNGTLIFSVISVLIVTQITFGSLVAGLNAGLLDKTIPFLAGKLMLED
LLFIKPLWYNIFENPVTVQFIHELIATLIFLVVIITLLILRLNLFPAYLLLICLCLQLTLGVLTFIYNVPIVLASLHQVT
AFILFAVNTYLLHYMKLSKLQYVK

Sequences:

>Translated_344_residues
MKIASDNREVCVGVKIWLCICCIGILLMVLVGGITRLTHSGLSITEWNPVIGVFPPIGERAWIREKIKYMATPEFKYLNF
NITLRGFRKLYLIEYFHRLLGRIVGLTFLIPFLYFTYKKKLHRNLIINFIVICLLILFQGVVGWFMVKSGLIDRPHVSHY
KLTAHLLLALLIFYLLWRQFLLSTISKVTYNIKVNGTLIFSVISVLIVTQITFGSLVAGLNAGLLDKTIPFLAGKLMLED
LLFIKPLWYNIFENPVTVQFIHELIATLIFLVVIITLLILRLNLFPAYLLLICLCLQLTLGVLTFIYNVPIVLASLHQVT
AFILFAVNTYLLHYMKLSKLQYVK
>Mature_344_residues
MKIASDNREVCVGVKIWLCICCIGILLMVLVGGITRLTHSGLSITEWNPVIGVFPPIGERAWIREKIKYMATPEFKYLNF
NITLRGFRKLYLIEYFHRLLGRIVGLTFLIPFLYFTYKKKLHRNLIINFIVICLLILFQGVVGWFMVKSGLIDRPHVSHY
KLTAHLLLALLIFYLLWRQFLLSTISKVTYNIKVNGTLIFSVISVLIVTQITFGSLVAGLNAGLLDKTIPFLAGKLMLED
LLFIKPLWYNIFENPVTVQFIHELIATLIFLVVIITLLILRLNLFPAYLLLICLCLQLTLGVLTFIYNVPIVLASLHQVT
AFILFAVNTYLLHYMKLSKLQYVK

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=351, Percent_Identity=32.7635327635328, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI17921987, Length=295, Percent_Identity=33.8983050847458, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17536069, Length=356, Percent_Identity=34.2696629213483, Blast_Score=190, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6320989, Length=359, Percent_Identity=34.5403899721448, Blast_Score=185, Evalue=8e-48,
Organism=Drosophila melanogaster, GI19922860, Length=358, Percent_Identity=32.6815642458101, Blast_Score=174, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_EHRCR (Q2GHG8)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507115.1
- STRING:   Q2GHG8
- GeneID:   3928051
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0294
- TIGR:   ECH_0294
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- PhylomeDB:   Q2GHG8
- ProtClustDB:   CLSK2761468
- BioCyc:   ECHA205920:ECH_0294-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 39513; Mature: 39513

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: BINDING 317-317

Signals:

None

Transmembrane regions:

HASH(0x1c145ad4)-; HASH(0x1d0d2ca8)-; HASH(0x1c82ca48)-; HASH(0x1bb52318)-; HASH(0x1d08e3ec)-; HASH(0x1b504404)-; HASH(0x1cb3c25c)-; HASH(0x1d091a04)-;

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIASDNREVCVGVKIWLCICCIGILLMVLVGGITRLTHSGLSITEWNPVIGVFPPIGER
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEECCCCCCCH
AWIREKIKYMATPEFKYLNFNITLRGFRKLYLIEYFHRLLGRIVGLTFLIPFLYFTYKKK
HHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHRNLIINFIVICLLILFQGVVGWFMVKSGLIDRPHVSHYKLTAHLLLALLIFYLLWRQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLSTISKVTYNIKVNGTLIFSVISVLIVTQITFGSLVAGLNAGLLDKTIPFLAGKLMLED
HHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLFIKPLWYNIFENPVTVQFIHELIATLIFLVVIITLLILRLNLFPAYLLLICLCLQLTL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLTFIYNVPIVLASLHQVTAFILFAVNTYLLHYMKLSKLQYVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MKIASDNREVCVGVKIWLCICCIGILLMVLVGGITRLTHSGLSITEWNPVIGVFPPIGER
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEECCCCCCCH
AWIREKIKYMATPEFKYLNFNITLRGFRKLYLIEYFHRLLGRIVGLTFLIPFLYFTYKKK
HHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHRNLIINFIVICLLILFQGVVGWFMVKSGLIDRPHVSHYKLTAHLLLALLIFYLLWRQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLSTISKVTYNIKVNGTLIFSVISVLIVTQITFGSLVAGLNAGLLDKTIPFLAGKLMLED
HHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLFIKPLWYNIFENPVTVQFIHELIATLIFLVVIITLLILRLNLFPAYLLLICLCLQLTL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLTFIYNVPIVLASLHQVTAFILFAVNTYLLHYMKLSKLQYVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA