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The map label for this gene is argJ [H]

Identifier: 88658175

GI number: 88658175

Start: 686358

End: 687623

Strand: Reverse

Name: argJ [H]

Synonym: ECH_0676

Alternate gene names: 88658175

Gene position: 687623-686358 (Counterclockwise)

Preceding gene: 88658021

Following gene: 88657831

Centisome position: 58.46

GC content: 32.86

Gene sequence:

>1266_bases
ATGGTCAAAAATTTTTCAAATAATCCAATTAGATTTCTTATTTCTCCTCTTGCTCCAACTAATTTTCCTGTTATGCCTGA
AGTTGATGGAGTTGAGTTGTATTCTTTTGCTTGTGGTATTAAAAACATTGTAGATGAACTTGATCTCCTAATAGTTAAGA
TGCCAGATAACACTAGTGTAGGTGGGGTATTTACAACATCTTATACAGCGAGTAGCAATGTTGAACATTGTAGGAAGATA
CTTCCTCATGGTAAGGCAAGGGTTTTAATTGTAAATTCTGGTAACTCCAATGTTGCTGTAGGTGTTGGAGGGTATAAAGC
CGTTGAAGAAATTACAAGGTTGTGTGCAGAAAGGTTTGATTGTTCTACTGAAGAAGTTTATTTTTGTTCTACAGGAATTA
TAGGTATTCCTTTGCCGGTTGAAAAAATTAAATCTGTAATACTAGATCCTATGTTGGGTAGTATTAAAAGCTCTTGGGAA
GATGCTGCTGATAGTATTACTACAACTGATACCTTTGTAAAGATGGTCACAAAGGAGGTATCAATTTGTGGTGAAAAAGT
TACCATAAATGGGATATGTAAAGGTTCAGGTATGGTTGCTCCAAATATGGCAACAATGTTAGCGTATGTTTTTACCAATG
CTAACATTAAGTCAGATGTATTACAGAAATTGTTGAAAGAGTATGTTAATGTATCTTTTAATAATATTACTGTTGATGGT
GATACATCTACTAGTGATTCAGTTTTAATATTTGCGACAAATCTTGCTAAACATAAGCAAGTATGTTCCGTTGATGATCA
AGCTCTTGATGACTTTAAAGTTGCTTTAAAAGATATGCTAGTGGAAATGGCACATTTAATTGTAAAAGATGGAGAAGGGG
TCACGAAATTTATTGCAATTAATATTAAAAATGCTACGTCAGTAGATGCTGCTAGAAAATTAGGTTTTTCAGTAGCAAAT
TCTTTGCTTGTCAAAACTGCTATAGCAGGTGGAGATGCTAATTGGGGTAGAATAATGATGGCTATAGGTAAAGCTGGGGA
ACCCTTTAATAAAAATGAAGTATCATTAAAAATAGGAACCCATGTAATATTAGTAAATGGTGAAATTAGTTCTACTTATG
ATAAAGCTTCTGTTAATCAATACGTAAAAAGTGAGCAAAATATTTATATCGAAGTTGATATTAATGCTGGTAATTTCGAT
GCAACTGTGTGGACCTGTGATTTAACTCATAGATTTGTTGATATTAATGGTAAGTATTTAACTTAA

Upstream 100 bases:

>100_bases
TTTAATATTACAAGCAAGTTTTAGTAATTTTTTTCAATAACTTTCTTGCATTATATGCATATACTTTATATAACTTAAGA
AGCATTAATTGGTAGTAGTA

Downstream 100 bases:

>100_bases
TTTGATAAGTAGTTTTTAGAGATCACAATGACTTTAAAAATAGCTACATGGAATGTCAACTCTATTAGGAAAAGGTTGGA
TCATTTATGTAATTGGCTAA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MVKNFSNNPIRFLISPLAPTNFPVMPEVDGVELYSFACGIKNIVDELDLLIVKMPDNTSVGGVFTTSYTASSNVEHCRKI
LPHGKARVLIVNSGNSNVAVGVGGYKAVEEITRLCAERFDCSTEEVYFCSTGIIGIPLPVEKIKSVILDPMLGSIKSSWE
DAADSITTTDTFVKMVTKEVSICGEKVTINGICKGSGMVAPNMATMLAYVFTNANIKSDVLQKLLKEYVNVSFNNITVDG
DTSTSDSVLIFATNLAKHKQVCSVDDQALDDFKVALKDMLVEMAHLIVKDGEGVTKFIAINIKNATSVDAARKLGFSVAN
SLLVKTAIAGGDANWGRIMMAIGKAGEPFNKNEVSLKIGTHVILVNGEISSTYDKASVNQYVKSEQNIYIEVDINAGNFD
ATVWTCDLTHRFVDINGKYLT

Sequences:

>Translated_421_residues
MVKNFSNNPIRFLISPLAPTNFPVMPEVDGVELYSFACGIKNIVDELDLLIVKMPDNTSVGGVFTTSYTASSNVEHCRKI
LPHGKARVLIVNSGNSNVAVGVGGYKAVEEITRLCAERFDCSTEEVYFCSTGIIGIPLPVEKIKSVILDPMLGSIKSSWE
DAADSITTTDTFVKMVTKEVSICGEKVTINGICKGSGMVAPNMATMLAYVFTNANIKSDVLQKLLKEYVNVSFNNITVDG
DTSTSDSVLIFATNLAKHKQVCSVDDQALDDFKVALKDMLVEMAHLIVKDGEGVTKFIAINIKNATSVDAARKLGFSVAN
SLLVKTAIAGGDANWGRIMMAIGKAGEPFNKNEVSLKIGTHVILVNGEISSTYDKASVNQYVKSEQNIYIEVDINAGNFD
ATVWTCDLTHRFVDINGKYLT
>Mature_421_residues
MVKNFSNNPIRFLISPLAPTNFPVMPEVDGVELYSFACGIKNIVDELDLLIVKMPDNTSVGGVFTTSYTASSNVEHCRKI
LPHGKARVLIVNSGNSNVAVGVGGYKAVEEITRLCAERFDCSTEEVYFCSTGIIGIPLPVEKIKSVILDPMLGSIKSSWE
DAADSITTTDTFVKMVTKEVSICGEKVTINGICKGSGMVAPNMATMLAYVFTNANIKSDVLQKLLKEYVNVSFNNITVDG
DTSTSDSVLIFATNLAKHKQVCSVDDQALDDFKVALKDMLVEMAHLIVKDGEGVTKFIAINIKNATSVDAARKLGFSVAN
SLLVKTAIAGGDANWGRIMMAIGKAGEPFNKNEVSLKIGTHVILVNGEISSTYDKASVNQYVKSEQNIYIEVDINAGNFD
ATVWTCDLTHRFVDINGKYLT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=382, Percent_Identity=34.0314136125654, Blast_Score=207, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 45571; Mature: 45571

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKNFSNNPIRFLISPLAPTNFPVMPEVDGVELYSFACGIKNIVDELDLLIVKMPDNTSV
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCC
GGVFTTSYTASSNVEHCRKILPHGKARVLIVNSGNSNVAVGVGGYKAVEEITRLCAERFD
CEEEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHC
CSTEEVYFCSTGIIGIPLPVEKIKSVILDPMLGSIKSSWEDAADSITTTDTFVKMVTKEV
CCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SICGEKVTINGICKGSGMVAPNMATMLAYVFTNANIKSDVLQKLLKEYVNVSFNNITVDG
HHCCCEEEEEEEECCCCEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEECEEEECC
DTSTSDSVLIFATNLAKHKQVCSVDDQALDDFKVALKDMLVEMAHLIVKDGEGVTKFIAI
CCCCCCCEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
NIKNATSVDAARKLGFSVANSLLVKTAIAGGDANWGRIMMAIGKAGEPFNKNEVSLKIGT
EECCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECE
HVILVNGEISSTYDKASVNQYVKSEQNIYIEVDINAGNFDATVWTCDLTHRFVDINGKYL
EEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEEEEEEEEECCCCEE
T
C
>Mature Secondary Structure
MVKNFSNNPIRFLISPLAPTNFPVMPEVDGVELYSFACGIKNIVDELDLLIVKMPDNTSV
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCC
GGVFTTSYTASSNVEHCRKILPHGKARVLIVNSGNSNVAVGVGGYKAVEEITRLCAERFD
CEEEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHC
CSTEEVYFCSTGIIGIPLPVEKIKSVILDPMLGSIKSSWEDAADSITTTDTFVKMVTKEV
CCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SICGEKVTINGICKGSGMVAPNMATMLAYVFTNANIKSDVLQKLLKEYVNVSFNNITVDG
HHCCCEEEEEEEECCCCEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEECEEEECC
DTSTSDSVLIFATNLAKHKQVCSVDDQALDDFKVALKDMLVEMAHLIVKDGEGVTKFIAI
CCCCCCCEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
NIKNATSVDAARKLGFSVANSLLVKTAIAGGDANWGRIMMAIGKAGEPFNKNEVSLKIGT
EECCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECE
HVILVNGEISSTYDKASVNQYVKSEQNIYIEVDINAGNFDATVWTCDLTHRFVDINGKYL
EEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEEEEEEEEECCCCEE
T
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]