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The map label for this gene is visC [C]

Identifier: 88657937

GI number: 88657937

Start: 16706

End: 17878

Strand: Direct

Name: visC [C]

Synonym: ECH_0020

Alternate gene names: 88657937

Gene position: 16706-17878 (Clockwise)

Preceding gene: 88657690

Following gene: 88658353

Centisome position: 1.42

GC content: 28.39

Gene sequence:

>1173_bases
ATGAACAATAGCAAGTACTATGACGTAGTTATCTCAGGAGCAGGGATCAATGGAATGATTACAGCAATAGCATTAAGTCA
ACTGTCTATCTCTACAGCTTTAATAGATAAAAACAAAATTTTACTATCAATACCAAAAGATAGAGTATTTGCCTTATCAA
GAAGATCCCAGGAAATATTAGATAAGTTTAACATATGGAACAATATAAAAGAGCATTGTCCTATATTAGACATCTTAATA
AAAGACGAAGATAGTTCAATATTTACACACTATGACCATAAATCTATAAGCGATAATCCTATGGGGTATATTGTAGAAAG
CAAATTTCTATGTGATGCCTTTAAAAAACATATAAAAAAAATAAACTTGTACTCAGAATGTACATACAAATCAGTAAACA
TTACAAATGATCTAGTAAGAATAGAACTAACAGACAATACAATATTATTAACATCATTATTAATATCTGCTGAAGGTAAA
AATTCAACCCTAAGACAAATATTTGATATACCATCTATCAATCATGATTATTCTCAAAGCAGTATTATTTGTAATATAAA
ACATACAAATCACCATAATAATCTAGCCATAGAGCATTTTTTTCATGGAGGACCATTTGCAATATTACCTATGTATGATG
GATACAGGTCTTCTGTGGTCTGGACAAATAAAACACAAATTAGTGAAATGCTTATGAAACTAAAAAAACAAGATTTTATG
GCAGAGTTAGAAAAAAAATGTGCACCTTATGTAAACGATATAAAACTAGATAGCGAAATAAAGTGTTTTCCATTACATTT
GATGTTTGCAAAACATTTATATAAGAACAGATTTGCATTGATAGGTGATGCAGCACATTCTATACATCCCATAGCAGGTC
AGGGGTTAAATTTAGGAATAAGAGACATTGATAAACTAGTAAACCATATAAAATCAGCAAAGCAATATGGTATAGATATA
GGTAGCAACTATGTATTAAAAAATTTTTCCTATGACAGATACTTTGATAACTCATCTATGGCAATTCTTACTACACTCAT
AGATGGAATATTTACTAAAAAATCTTGTACAGCAAAAATTGCAAGAAGATTTGGATTATTTATTGTTCAAAATTCAAAAA
GCATAAAAAATTATATGATAAAACATGCTATGGGAATAGGAAAATTTAACTAA

Upstream 100 bases:

>100_bases
AAGCTGTGGGTCAGGGGTTCGAATCCCTTCGGGCACACCATAAAATTGACAATTTTTAATTATTAATACACTTTTTTATA
CTTTTGCGTATTTTTGTATC

Downstream 100 bases:

>100_bases
CTCTTGTCAATTACATTATCACAATCCTCCTTTTTATTTTTCATGCACAAAATCTCTACAGTCATTTTATTGATTGATTT
TTCTATCTCCATCATTGCAT

Product: UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNNSKYYDVVISGAGINGMITAIALSQLSISTALIDKNKILLSIPKDRVFALSRRSQEILDKFNIWNNIKEHCPILDILI
KDEDSSIFTHYDHKSISDNPMGYIVESKFLCDAFKKHIKKINLYSECTYKSVNITNDLVRIELTDNTILLTSLLISAEGK
NSTLRQIFDIPSINHDYSQSSIICNIKHTNHHNNLAIEHFFHGGPFAILPMYDGYRSSVVWTNKTQISEMLMKLKKQDFM
AELEKKCAPYVNDIKLDSEIKCFPLHLMFAKHLYKNRFALIGDAAHSIHPIAGQGLNLGIRDIDKLVNHIKSAKQYGIDI
GSNYVLKNFSYDRYFDNSSMAILTTLIDGIFTKKSCTAKIARRFGLFIVQNSKSIKNYMIKHAMGIGKFN

Sequences:

>Translated_390_residues
MNNSKYYDVVISGAGINGMITAIALSQLSISTALIDKNKILLSIPKDRVFALSRRSQEILDKFNIWNNIKEHCPILDILI
KDEDSSIFTHYDHKSISDNPMGYIVESKFLCDAFKKHIKKINLYSECTYKSVNITNDLVRIELTDNTILLTSLLISAEGK
NSTLRQIFDIPSINHDYSQSSIICNIKHTNHHNNLAIEHFFHGGPFAILPMYDGYRSSVVWTNKTQISEMLMKLKKQDFM
AELEKKCAPYVNDIKLDSEIKCFPLHLMFAKHLYKNRFALIGDAAHSIHPIAGQGLNLGIRDIDKLVNHIKSAKQYGIDI
GSNYVLKNFSYDRYFDNSSMAILTTLIDGIFTKKSCTAKIARRFGLFIVQNSKSIKNYMIKHAMGIGKFN
>Mature_390_residues
MNNSKYYDVVISGAGINGMITAIALSQLSISTALIDKNKILLSIPKDRVFALSRRSQEILDKFNIWNNIKEHCPILDILI
KDEDSSIFTHYDHKSISDNPMGYIVESKFLCDAFKKHIKKINLYSECTYKSVNITNDLVRIELTDNTILLTSLLISAEGK
NSTLRQIFDIPSINHDYSQSSIICNIKHTNHHNNLAIEHFFHGGPFAILPMYDGYRSSVVWTNKTQISEMLMKLKKQDFM
AELEKKCAPYVNDIKLDSEIKCFPLHLMFAKHLYKNRFALIGDAAHSIHPIAGQGLNLGIRDIDKLVNHIKSAKQYGIDI
GSNYVLKNFSYDRYFDNSSMAILTTLIDGIFTKKSCTAKIARRFGLFIVQNSKSIKNYMIKHAMGIGKFN

Specific function: Not Yet Known. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=386, Percent_Identity=26.6839378238342, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI32967307, Length=352, Percent_Identity=26.9886363636364, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1789273, Length=392, Percent_Identity=28.0612244897959, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786883, Length=390, Percent_Identity=27.1794871794872, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789274, Length=390, Percent_Identity=24.8717948717949, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI25146631, Length=438, Percent_Identity=25.7990867579909, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6321694, Length=294, Percent_Identity=27.2108843537415, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920760, Length=437, Percent_Identity=24.0274599542334, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44374; Mature: 44374

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS01304 UBIH ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSKYYDVVISGAGINGMITAIALSQLSISTALIDKNKILLSIPKDRVFALSRRSQEIL
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEEEEECCEEEEECCCCHHHHHHHHHHHHH
DKFNIWNNIKEHCPILDILIKDEDSSIFTHYDHKSISDNPMGYIVESKFLCDAFKKHIKK
HHHHHHHHHHHHCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHH
INLYSECTYKSVNITNDLVRIELTDNTILLTSLLISAEGKNSTLRQIFDIPSINHDYSQS
CCCHHHCCEEEEECCCCEEEEEECCCEEEEEEHHHCCCCCCHHHHHHHCCCCCCCCCCCC
SIICNIKHTNHHNNLAIEHFFHGGPFAILPMYDGYRSSVVWTNKTQISEMLMKLKKQDFM
EEEEEEEECCCCCCEEEEEEECCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHH
AELEKKCAPYVNDIKLDSEIKCFPLHLMFAKHLYKNRFALIGDAAHSIHPIAGQGLNLGI
HHHHHHHCCCHHCEEECCCCEEEHHHHHHHHHHHHCCEEEEECCHHCCCCCCCCCCCCCH
RDIDKLVNHIKSAKQYGIDIGSNYVLKNFSYDRYFDNSSMAILTTLIDGIFTKKSCTAKI
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHH
ARRFGLFIVQNSKSIKNYMIKHAMGIGKFN
HHHHCEEEEECCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNNSKYYDVVISGAGINGMITAIALSQLSISTALIDKNKILLSIPKDRVFALSRRSQEIL
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEEEEECCEEEEECCCCHHHHHHHHHHHHH
DKFNIWNNIKEHCPILDILIKDEDSSIFTHYDHKSISDNPMGYIVESKFLCDAFKKHIKK
HHHHHHHHHHHHCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHH
INLYSECTYKSVNITNDLVRIELTDNTILLTSLLISAEGKNSTLRQIFDIPSINHDYSQS
CCCHHHCCEEEEECCCCEEEEEECCCEEEEEEHHHCCCCCCHHHHHHHCCCCCCCCCCCC
SIICNIKHTNHHNNLAIEHFFHGGPFAILPMYDGYRSSVVWTNKTQISEMLMKLKKQDFM
EEEEEEEECCCCCCEEEEEEECCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHH
AELEKKCAPYVNDIKLDSEIKCFPLHLMFAKHLYKNRFALIGDAAHSIHPIAGQGLNLGI
HHHHHHHCCCHHCEEECCCCEEEHHHHHHHHHHHHCCEEEEECCHHCCCCCCCCCCCCCH
RDIDKLVNHIKSAKQYGIDIGSNYVLKNFSYDRYFDNSSMAILTTLIDGIFTKKSCTAKI
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCHHHHHHHHHHHHCCHHHHHHH
ARRFGLFIVQNSKSIKNYMIKHAMGIGKFN
HHHHCEEEEECCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]