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The map label for this gene is glyQ [H]

Identifier: 88658353

GI number: 88658353

Start: 18789

End: 19631

Strand: Direct

Name: glyQ [H]

Synonym: ECH_0023

Alternate gene names: 88658353

Gene position: 18789-19631 (Clockwise)

Preceding gene: 88657937

Following gene: 88657718

Centisome position: 1.6

GC content: 32.86

Gene sequence:

>843_bases
GTGAATTTTCAAAGTATAATAAGAAACTTACAAAGTTATTGGGAAGACTATGGATGTACAATATTTCAGCCATATACTTC
TGAATTAGGAGCAGCAACTCTTCATCCAGCAACTTCGATGACAGCTATATCAAAAAAGCCATCAAAACTGGCTTATGTTC
AACCTGTTATTAGGCCATGTGATGGAAGATACGGTGATAATCCAAATCGTTTATATCAGCACCATCAATATCAAGTATTA
ATCAAACCTTCTAATACCGATTTACAATCAGATTATTTAAAAAGTTTAGAAAGAATAGGAATATCTATCAAAACTCACGA
CATAAAATTTATAGAAGACGATTGGGAAAATCCAAGCATTGGTGCTTGGGGTTTAGGATGGGAAGTAACCTGTAATGGTA
TGGAGATAACTCAATTTACTTATATGCAACAAGTAGGTGGTATTGAATGTTCTTTAGTTCCAGGAGAAATTGCATATGGC
CTGGAAAGGATAGCGATGATAATTCAAAATGTTGACAATATATATAAAATATTATGGGATGATAATGGAACAACTTACGG
AGACGTATTCAAACAACGCGAATATGAATTTTCTAAACTAGCTTTAGATTATTATGATGTAGACATTCTATTTAAGCAGT
TTAATGAAGCTGAACAAACATGTATTTCTTTAATAGAAAAAAAACTACCATTAGCAGCATATGATGTTTGCACGAAAGCT
AGTCATATCCTTAATTTGCTTGAATCTCGTGGAGTCATTGGAGTTAACGAACGTGCGTCTTATATATTACGCGTACGTAA
ACTTGCAAATTTATGTTGTAGCTTATATACTCAGTGTCATTAA

Upstream 100 bases:

>100_bases
TATAACTTTTAATAAGTTATATATTTAATAAAAAAATAAACCTTGTATAACTTCATATTATTCTTCTATAATAGCGATAA
TTAGGATTGGTTATATTTTT

Downstream 100 bases:

>100_bases
AATAAGTAAAACGACATGCCTTTAGAACTATTATTTGAATGCTTATCAGAAGAAACACCTCCTGAGATGCAGAGTAGTGC
ATATGCATACATGGATTCTT

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MNFQSIIRNLQSYWEDYGCTIFQPYTSELGAATLHPATSMTAISKKPSKLAYVQPVIRPCDGRYGDNPNRLYQHHQYQVL
IKPSNTDLQSDYLKSLERIGISIKTHDIKFIEDDWENPSIGAWGLGWEVTCNGMEITQFTYMQQVGGIECSLVPGEIAYG
LERIAMIIQNVDNIYKILWDDNGTTYGDVFKQREYEFSKLALDYYDVDILFKQFNEAEQTCISLIEKKLPLAAYDVCTKA
SHILNLLESRGVIGVNERASYILRVRKLANLCCSLYTQCH

Sequences:

>Translated_280_residues
MNFQSIIRNLQSYWEDYGCTIFQPYTSELGAATLHPATSMTAISKKPSKLAYVQPVIRPCDGRYGDNPNRLYQHHQYQVL
IKPSNTDLQSDYLKSLERIGISIKTHDIKFIEDDWENPSIGAWGLGWEVTCNGMEITQFTYMQQVGGIECSLVPGEIAYG
LERIAMIIQNVDNIYKILWDDNGTTYGDVFKQREYEFSKLALDYYDVDILFKQFNEAEQTCISLIEKKLPLAAYDVCTKA
SHILNLLESRGVIGVNERASYILRVRKLANLCCSLYTQCH
>Mature_280_residues
MNFQSIIRNLQSYWEDYGCTIFQPYTSELGAATLHPATSMTAISKKPSKLAYVQPVIRPCDGRYGDNPNRLYQHHQYQVL
IKPSNTDLQSDYLKSLERIGISIKTHDIKFIEDDWENPSIGAWGLGWEVTCNGMEITQFTYMQQVGGIECSLVPGEIAYG
LERIAMIIQNVDNIYKILWDDNGTTYGDVFKQREYEFSKLALDYYDVDILFKQFNEAEQTCISLIEKKLPLAAYDVCTKA
SHILNLLESRGVIGVNERASYILRVRKLANLCCSLYTQCH

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1789983, Length=280, Percent_Identity=52.8571428571429, Blast_Score=307, Evalue=5e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006194
- InterPro:   IPR002310 [H]

Pfam domain/function: PF02091 tRNA-synt_2e [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 32060; Mature: 32060

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQSIIRNLQSYWEDYGCTIFQPYTSELGAATLHPATSMTAISKKPSKLAYVQPVIRPC
CCHHHHHHHHHHHHHHCCCEEECCHHHHCCCEEECCCHHHHHHCCCCCHHHHHHHHHHCC
DGRYGDNPNRLYQHHQYQVLIKPSNTDLQSDYLKSLERIGISIKTHDIKFIEDDWENPSI
CCCCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCEEEECCEEEEECCCCCCCC
GAWGLGWEVTCNGMEITQFTYMQQVGGIECSLVPGEIAYGLERIAMIIQNVDNIYKILWD
CEECCCCEEEECCEEHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHEEEEEC
DNGTTYGDVFKQREYEFSKLALDYYDVDILFKQFNEAEQTCISLIEKKLPLAAYDVCTKA
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
SHILNLLESRGVIGVNERASYILRVRKLANLCCSLYTQCH
HHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFQSIIRNLQSYWEDYGCTIFQPYTSELGAATLHPATSMTAISKKPSKLAYVQPVIRPC
CCHHHHHHHHHHHHHHCCCEEECCHHHHCCCEEECCCHHHHHHCCCCCHHHHHHHHHHCC
DGRYGDNPNRLYQHHQYQVLIKPSNTDLQSDYLKSLERIGISIKTHDIKFIEDDWENPSI
CCCCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCEEEECCEEEEECCCCCCCC
GAWGLGWEVTCNGMEITQFTYMQQVGGIECSLVPGEIAYGLERIAMIIQNVDNIYKILWD
CEECCCCEEEECCEEHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHEEEEEC
DNGTTYGDVFKQREYEFSKLALDYYDVDILFKQFNEAEQTCISLIEKKLPLAAYDVCTKA
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
SHILNLLESRGVIGVNERASYILRVRKLANLCCSLYTQCH
HHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA