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The map label for this gene is ccmB [H]

Identifier: 88657935

GI number: 88657935

Start: 59701

End: 60363

Strand: Direct

Name: ccmB [H]

Synonym: ECH_0065

Alternate gene names: 88657935

Gene position: 59701-60363 (Clockwise)

Preceding gene: 88658323

Following gene: 88658657

Centisome position: 5.08

GC content: 28.96

Gene sequence:

>663_bases
ATGGGCAATAGTAGTGCATTAATGTATGAATTAAAGTTATCGATGAGTAGGAAAGGTAATCTTTTAAATGCAATTATTCT
TTTTATATTAATAATTAGTACAGCATTGTTTACTATGAAAAATGTTGAAATAATAAAAGTACTTCCAACTATTTTATGGA
TTTGTAGTATTTCTGCTGTACATATGTCTATGTGTCATTTATTTGAAAATGACTATGCTAATGGCTCTTTAGAGCAAATG
TTGATACAGGAAAGTATGGTAGAGTTGATAATATTTTTTAAGATTTTATCGCATTGGATTTGTGTAGGAATACCAGTAAG
TATTATTTCTATGTTTATAGATTTTATAATTCTGGAAAGTAACATATATACTACTCTAGGATTAGGGTTGTCTCTAGGAA
TTAGCTTGCTAGTAATTAGCTTTATATCAGCTGTAGGTGAAGCGTTAGTATTGGGTAGAGGTAGTGGCATAATAATAGCT
CAGATTTTGACATTACCTATTATGATACCGGTGTTAGTATATTTTAGTCTTGTATTTGATAGTATAATAAATGGTGTATA
CAGAGAAAATTTAATGTTGCTTGGATTAATTATTGCTGGGGTAGTTCCTATTAGTGTGATATTTGTATCATTTGCAATTA
GAGTTGCTGTTGAATATGATTAG

Upstream 100 bases:

>100_bases
TTTGTGATACAACTAAAATAATAATTTAAATATAGTTGATTAAGAATTCGTGTATGATATGTGATATAATGACGATGTTT
TTATCAGTTGTGGGCTGAGT

Downstream 100 bases:

>100_bases
CTATACGAAATATTTTTTGATGTTTGATTTTATATTTAACAATTTGAAAAATAGTATGCGCTAGGAAGATTTTAGTTACT
TGAATTAATATGTTAGTTAA

Product: putative heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MGNSSALMYELKLSMSRKGNLLNAIILFILIISTALFTMKNVEIIKVLPTILWICSISAVHMSMCHLFENDYANGSLEQM
LIQESMVELIIFFKILSHWICVGIPVSIISMFIDFIILESNIYTTLGLGLSLGISLLVISFISAVGEALVLGRGSGIIIA
QILTLPIMIPVLVYFSLVFDSIINGVYRENLMLLGLIIAGVVPISVIFVSFAIRVAVEYD

Sequences:

>Translated_220_residues
MGNSSALMYELKLSMSRKGNLLNAIILFILIISTALFTMKNVEIIKVLPTILWICSISAVHMSMCHLFENDYANGSLEQM
LIQESMVELIIFFKILSHWICVGIPVSIISMFIDFIILESNIYTTLGLGLSLGISLLVISFISAVGEALVLGRGSGIIIA
QILTLPIMIPVLVYFSLVFDSIINGVYRENLMLLGLIIAGVVPISVIFVSFAIRVAVEYD
>Mature_219_residues
GNSSALMYELKLSMSRKGNLLNAIILFILIISTALFTMKNVEIIKVLPTILWICSISAVHMSMCHLFENDYANGSLEQML
IQESMVELIIFFKILSHWICVGIPVSIISMFIDFIILESNIYTTLGLGLSLGISLLVISFISAVGEALVLGRGSGIIIAQ
ILTLPIMIPVLVYFSLVFDSIINGVYRENLMLLGLIIAGVVPISVIFVSFAIRVAVEYD

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=214, Percent_Identity=24.2990654205607, Blast_Score=77, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 24209; Mature: 24078

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNSSALMYELKLSMSRKGNLLNAIILFILIISTALFTMKNVEIIKVLPTILWICSISAV
CCCCHHEEHHEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
HMSMCHLFENDYANGSLEQMLIQESMVELIIFFKILSHWICVGIPVSIISMFIDFIILES
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
NIYTTLGLGLSLGISLLVISFISAVGEALVLGRGSGIIIAQILTLPIMIPVLVYFSLVFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SIINGVYRENLMLLGLIIAGVVPISVIFVSFAIRVAVEYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
GNSSALMYELKLSMSRKGNLLNAIILFILIISTALFTMKNVEIIKVLPTILWICSISAV
CCCHHEEHHEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
HMSMCHLFENDYANGSLEQMLIQESMVELIIFFKILSHWICVGIPVSIISMFIDFIILES
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
NIYTTLGLGLSLGISLLVISFISAVGEALVLGRGSGIIIAQILTLPIMIPVLVYFSLVFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SIINGVYRENLMLLGLIIAGVVPISVIFVSFAIRVAVEYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]