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The map label for this gene is thiO [H]

Identifier: 88657874

GI number: 88657874

Start: 430003

End: 431067

Strand: Direct

Name: thiO [H]

Synonym: ECH_0452

Alternate gene names: 88657874

Gene position: 430003-431067 (Clockwise)

Preceding gene: 88658191

Following gene: 88658656

Centisome position: 36.56

GC content: 32.02

Gene sequence:

>1065_bases
ATGAATAAAAAAGCAGGGGTTGTAGGCGCAGGATTAGTAGGTAGATTATTAGCGTTAAGGCTATTACATGATGGTTGGCA
AGTTACTTTGTTTGATAAATTTGGTAAAAATGATAGACGAAGTTGTGGTGCTATTGCTGCAGGTATGCTTGCTTTATATT
CAGAATCAGAAAAAATGGAGCAAATAGTTTTTGATTTAGGTATAAAGTCATTAAATTTGTGGCCAAAAATTCTCAATAGT
ATGTTGGGTAATACTTCTTTTAAGATGCTTGGCAGTATAGTAGTAGCTCACAGAAATGACATGTCAGACCTTGAAAGAAT
GATGATGCTTATAAAAAGAAAATCACATGTTAGTAATTTAGAGATAATAGATGAGAATGCTTTAAAAATATTTGAACCTG
ATCTCTCTTTTCCTTATGGATTATATATACCAGGAGAGGCACAAATTGATAGCTCTCAGCTCTTTTATAATATAATGCGT
ACTTTAGAACAATATAATGTTACTTGGTATGAACATGTTGTTGTTGATAAAATTATAGATGAAATTGTGGTTATAGAAAG
TGGTAAAGAATATAGGTTTGATTTTGTTTTTGATTGTCGAGGTATAGGAGCAAAAAGTGATTTGCCTAATATAAGAGGGG
TGAGAGGTGAAGTATTGTTATTACATGCTCCACAAGTTAATTTAAACAGACCAATTAGAATGGTGCATCCCAGGTATAGT
ATATATATAGTTCCTAGACAGAATTTTCAATTTGTTATTGGAGCTACTGAAATAGAAAGTTGTGATATGTCTGAAGTTTC
AGTACAATCTGTACTAGAGTTACTATCTGCTGCTTATTCAGTGCATAAGGGTTTTGCTGAAGCAAGAATTATAGATATGT
CAGTGAATTGTAGAGCAGCCTTTTCTGATAATTTACCTAAAATATATGTTCATAATAATCTTATTAGGATTAATGGTCTG
TATAGGCATGGGTATTTATTAGCTCCGTCGTTGATAGAAGAAGTAGTATTGTTGCTTAATGGAAACTTGAATACTCATTC
CTCAATTATTGAAATGGTTAGCTAA

Upstream 100 bases:

>100_bases
GTAGGATTTCATGTTTTTATTAAGATGCTTTTAAGGTATGAAATGAGAAATTATGTTACTATAAAGATTATTGTTTGGAA
ATTTTATACTAGATTTGATC

Downstream 100 bases:

>100_bases
TATAGAGTAATAATGATTTTGTTTTAGGTAGTCATATTCTGATAATTTACCTAGAATATATGTTCATAATAATCTTATTA
GGATTAATATCTGTATTGGC

Product: FAD-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNKKAGVVGAGLVGRLLALRLLHDGWQVTLFDKFGKNDRRSCGAIAAGMLALYSESEKMEQIVFDLGIKSLNLWPKILNS
MLGNTSFKMLGSIVVAHRNDMSDLERMMMLIKRKSHVSNLEIIDENALKIFEPDLSFPYGLYIPGEAQIDSSQLFYNIMR
TLEQYNVTWYEHVVVDKIIDEIVVIESGKEYRFDFVFDCRGIGAKSDLPNIRGVRGEVLLLHAPQVNLNRPIRMVHPRYS
IYIVPRQNFQFVIGATEIESCDMSEVSVQSVLELLSAAYSVHKGFAEARIIDMSVNCRAAFSDNLPKIYVHNNLIRINGL
YRHGYLLAPSLIEEVVLLLNGNLNTHSSIIEMVS

Sequences:

>Translated_354_residues
MNKKAGVVGAGLVGRLLALRLLHDGWQVTLFDKFGKNDRRSCGAIAAGMLALYSESEKMEQIVFDLGIKSLNLWPKILNS
MLGNTSFKMLGSIVVAHRNDMSDLERMMMLIKRKSHVSNLEIIDENALKIFEPDLSFPYGLYIPGEAQIDSSQLFYNIMR
TLEQYNVTWYEHVVVDKIIDEIVVIESGKEYRFDFVFDCRGIGAKSDLPNIRGVRGEVLLLHAPQVNLNRPIRMVHPRYS
IYIVPRQNFQFVIGATEIESCDMSEVSVQSVLELLSAAYSVHKGFAEARIIDMSVNCRAAFSDNLPKIYVHNNLIRINGL
YRHGYLLAPSLIEEVVLLLNGNLNTHSSIIEMVS
>Mature_354_residues
MNKKAGVVGAGLVGRLLALRLLHDGWQVTLFDKFGKNDRRSCGAIAAGMLALYSESEKMEQIVFDLGIKSLNLWPKILNS
MLGNTSFKMLGSIVVAHRNDMSDLERMMMLIKRKSHVSNLEIIDENALKIFEPDLSFPYGLYIPGEAQIDSSQLFYNIMR
TLEQYNVTWYEHVVVDKIIDEIVVIESGKEYRFDFVFDCRGIGAKSDLPNIRGVRGEVLLLHAPQVNLNRPIRMVHPRYS
IYIVPRQNFQFVIGATEIESCDMSEVSVQSVLELLSAAYSVHKGFAEARIIDMSVNCRAAFSDNLPKIYVHNNLIRINGL
YRHGYLLAPSLIEEVVLLLNGNLNTHSSIIEMVS

Specific function: May have amino acid oxidase activity in the biosynthesis of thiazole when cysteine gives its thiol group to be inserted into the thiazole molecule and the rest of the molecule is deaminated to give pyruvic acid and ammonia [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: NA

Molecular weight: Translated: 39983; Mature: 39983

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKAGVVGAGLVGRLLALRLLHDGWQVTLFDKFGKNDRRSCGAIAAGMLALYSESEKME
CCCCCCEECHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHH
QIVFDLGIKSLNLWPKILNSMLGNTSFKMLGSIVVAHRNDMSDLERMMMLIKRKSHVSNL
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCCCE
EIIDENALKIFEPDLSFPYGLYIPGEAQIDSSQLFYNIMRTLEQYNVTWYEHVVVDKIID
EEEECCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EIVVIESGKEYRFDFVFDCRGIGAKSDLPNIRGVRGEVLLLHAPQVNLNRPIRMVHPRYS
HEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCEE
IYIVPRQNFQFVIGATEIESCDMSEVSVQSVLELLSAAYSVHKGFAEARIIDMSVNCRAA
EEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEE
FSDNLPKIYVHNNLIRINGLYRHGYLLAPSLIEEVVLLLNGNLNTHSSIIEMVS
CCCCCCEEEEECCEEEEEEEEECCEEECHHHHHHHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure
MNKKAGVVGAGLVGRLLALRLLHDGWQVTLFDKFGKNDRRSCGAIAAGMLALYSESEKME
CCCCCCEECHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHH
QIVFDLGIKSLNLWPKILNSMLGNTSFKMLGSIVVAHRNDMSDLERMMMLIKRKSHVSNL
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCCCE
EIIDENALKIFEPDLSFPYGLYIPGEAQIDSSQLFYNIMRTLEQYNVTWYEHVVVDKIID
EEEECCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EIVVIESGKEYRFDFVFDCRGIGAKSDLPNIRGVRGEVLLLHAPQVNLNRPIRMVHPRYS
HEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCEE
IYIVPRQNFQFVIGATEIESCDMSEVSVQSVLELLSAAYSVHKGFAEARIIDMSVNCRAA
EEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEE
FSDNLPKIYVHNNLIRINGLYRHGYLLAPSLIEEVVLLLNGNLNTHSSIIEMVS
CCCCCCEEEEECCEEEEEEEEECCEEECHHHHHHHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371431 [H]