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The map label for this gene is engA [H]

Identifier: 88657837

GI number: 88657837

Start: 506393

End: 507721

Strand: Direct

Name: engA [H]

Synonym: ECH_0504

Alternate gene names: 88657837

Gene position: 506393-507721 (Clockwise)

Preceding gene: 88658162

Following gene: 88658454

Centisome position: 43.05

GC content: 28.07

Gene sequence:

>1329_bases
ATGTTGAAAATAGCTATAGTTGGGTTACCTAATGTTGGAAAATCTACTATTTTTAATAGATTAACTAGTCAAAAATCTGC
AATTGTTAGCAATATTCCTAATTTGACAAGAGATAGAAGGGAAGGGGATGCTGATTTATGTGGATTGAAATTTAAGATTG
TTGATACGGGTGGAGTGGATAATACAATAAAATTATCTTCATTAGTACTCGATCAAGTAAAATTATCTATAGAAGAGTCT
GATATAATATTTTTCGTTGTTGATGCAAGGATTGAACATGATGATAAAAATATAGAGTTTGCAAAATATTTAAGAAAGAA
GGTAAAAAAACCTATAATATTAATTGCGAATAAATGTGAAAGTCAAAAGAGATGTTATAGTATAGATTATTTAGGGTATT
TTGATTTTATAGGTCCAGTTTATATTTCTGCAGAACATAATTTAGGTTTAGTGGATTTATATGAAGCGTTGTTGCCATTT
ATTAAAGAATATGATTTAAATACATTAGATTTACATAATATTAAGCTTTCTATTGTTGGGAGACCAAATGCTGGTAAATC
AACTTTTATTAATAGGTTGCTTGCTGAAAATAGAATGATTGTAAGTCCTGAACCTGGAACAACTAGAGATTCTATAGATG
TAGAATATACATATAGAGGTCAGAAATTTACATTGATTGATACTGCTGGCATGCGTAAAAAAGCAAAGGTAACTGAAAGT
ATAGAAGTGACTTCTGTTCACAAGACTATTGAGTCAATTAATAGGTCTGATATTGTGATTTTGATGATAGATTCTGTTTA
TGGTATAGAGCAACAAGATTTATCTATTGCTGAACTTGCTATACAAAAAGGTAAAGCTATTATTATTGCTTTAAACAAAT
GGGATATGATTGCTAAAAAAGATAGATCTGAGTTGCTAAAAGATATTTGTAATTATAATAAATTGAATTTTAAAGTTCCG
GTTATTGAAGTTTCTGCACTTAAAAATATTAATTGTAATAAAATAATAGAAACAAGCATAGAGCTATATAAATGTCTGAC
AATGCGTATTAGTACTTCTGTGCTGAATAAATGGTTAAAATTAGCTGTAGAATACCATAAACCTCCATTGTGTAATGGCA
AGGTAGTGAAGATCAAATACATTACACAAGTTAAAGTAATACCTCCAACTTTTATTGCAGTTGTTAATGGTTCTTATAGT
ATTGATTTAACTTATAGGCAATATTTAATGAGTAGTTTGAGGAAGCATTTTTCTATTGATGGGATTCCAATAAGGTTAAA
TTTTAAAAAGAATAAGAATCCATATGATGATAGTTATTCTAAATCTTAA

Upstream 100 bases:

>100_bases
GATAATATGTTATCCATAGGATCAACAGTAATATTGTGCTATACTCAATAACTTTAAATAATGTCTGGCTGTATAGTATA
TCATAAGTGTAGAATTTTTT

Downstream 100 bases:

>100_bases
AGCAATTTCTTAATTGAATGTGTTAAGATTAGTATCAATGACTTTGAATTTTATTATAATTTTATATGTATTCAATCAAT
GAAATACCTGTCATTTCCTT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MLKIAIVGLPNVGKSTIFNRLTSQKSAIVSNIPNLTRDRREGDADLCGLKFKIVDTGGVDNTIKLSSLVLDQVKLSIEES
DIIFFVVDARIEHDDKNIEFAKYLRKKVKKPIILIANKCESQKRCYSIDYLGYFDFIGPVYISAEHNLGLVDLYEALLPF
IKEYDLNTLDLHNIKLSIVGRPNAGKSTFINRLLAENRMIVSPEPGTTRDSIDVEYTYRGQKFTLIDTAGMRKKAKVTES
IEVTSVHKTIESINRSDIVILMIDSVYGIEQQDLSIAELAIQKGKAIIIALNKWDMIAKKDRSELLKDICNYNKLNFKVP
VIEVSALKNINCNKIIETSIELYKCLTMRISTSVLNKWLKLAVEYHKPPLCNGKVVKIKYITQVKVIPPTFIAVVNGSYS
IDLTYRQYLMSSLRKHFSIDGIPIRLNFKKNKNPYDDSYSKS

Sequences:

>Translated_442_residues
MLKIAIVGLPNVGKSTIFNRLTSQKSAIVSNIPNLTRDRREGDADLCGLKFKIVDTGGVDNTIKLSSLVLDQVKLSIEES
DIIFFVVDARIEHDDKNIEFAKYLRKKVKKPIILIANKCESQKRCYSIDYLGYFDFIGPVYISAEHNLGLVDLYEALLPF
IKEYDLNTLDLHNIKLSIVGRPNAGKSTFINRLLAENRMIVSPEPGTTRDSIDVEYTYRGQKFTLIDTAGMRKKAKVTES
IEVTSVHKTIESINRSDIVILMIDSVYGIEQQDLSIAELAIQKGKAIIIALNKWDMIAKKDRSELLKDICNYNKLNFKVP
VIEVSALKNINCNKIIETSIELYKCLTMRISTSVLNKWLKLAVEYHKPPLCNGKVVKIKYITQVKVIPPTFIAVVNGSYS
IDLTYRQYLMSSLRKHFSIDGIPIRLNFKKNKNPYDDSYSKS
>Mature_442_residues
MLKIAIVGLPNVGKSTIFNRLTSQKSAIVSNIPNLTRDRREGDADLCGLKFKIVDTGGVDNTIKLSSLVLDQVKLSIEES
DIIFFVVDARIEHDDKNIEFAKYLRKKVKKPIILIANKCESQKRCYSIDYLGYFDFIGPVYISAEHNLGLVDLYEALLPF
IKEYDLNTLDLHNIKLSIVGRPNAGKSTFINRLLAENRMIVSPEPGTTRDSIDVEYTYRGQKFTLIDTAGMRKKAKVTES
IEVTSVHKTIESINRSDIVILMIDSVYGIEQQDLSIAELAIQKGKAIIIALNKWDMIAKKDRSELLKDICNYNKLNFKVP
VIEVSALKNINCNKIIETSIELYKCLTMRISTSVLNKWLKLAVEYHKPPLCNGKVVKIKYITQVKVIPPTFIAVVNGSYS
IDLTYRQYLMSSLRKHFSIDGIPIRLNFKKNKNPYDDSYSKS

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=474, Percent_Identity=37.3417721518987, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI2367268, Length=132, Percent_Identity=31.0606060606061, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=179, Percent_Identity=28.4916201117318, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=214, Percent_Identity=28.9719626168224, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50158; Mature: 50158

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIAIVGLPNVGKSTIFNRLTSQKSAIVSNIPNLTRDRREGDADLCGLKFKIVDTGGVD
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEEEEEECCCCC
NTIKLSSLVLDQVKLSIEESDIIFFVVDARIEHDDKNIEFAKYLRKKVKKPIILIANKCE
CEEEHHHHHHHHHHEEEECCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCC
SQKRCYSIDYLGYFDFIGPVYISAEHNLGLVDLYEALLPFIKEYDLNTLDLHNIKLSIVG
CCCCEEEEEECHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEE
RPNAGKSTFINRLLAENRMIVSPEPGTTRDSIDVEYTYRGQKFTLIDTAGMRKKAKVTES
CCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEECCCEEEEEECCCCCCHHHHHCC
IEVTSVHKTIESINRSDIVILMIDSVYGIEQQDLSIAELAIQKGKAIIIALNKWDMIAKK
EEHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHH
DRSELLKDICNYNKLNFKVPVIEVSALKNINCNKIIETSIELYKCLTMRISTSVLNKWLK
HHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVEYHKPPLCNGKVVKIKYITQVKVIPPTFIAVVNGSYSIDLTYRQYLMSSLRKHFSID
HHHHHCCCCCCCCEEEEEEEEEEEEECCCEEEEEECCCEEEEHHHHHHHHHHHHHHCCCC
GIPIRLNFKKNKNPYDDSYSKS
CEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLKIAIVGLPNVGKSTIFNRLTSQKSAIVSNIPNLTRDRREGDADLCGLKFKIVDTGGVD
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEEEEEECCCCC
NTIKLSSLVLDQVKLSIEESDIIFFVVDARIEHDDKNIEFAKYLRKKVKKPIILIANKCE
CEEEHHHHHHHHHHEEEECCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCC
SQKRCYSIDYLGYFDFIGPVYISAEHNLGLVDLYEALLPFIKEYDLNTLDLHNIKLSIVG
CCCCEEEEEECHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEE
RPNAGKSTFINRLLAENRMIVSPEPGTTRDSIDVEYTYRGQKFTLIDTAGMRKKAKVTES
CCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEECCCEEEEEECCCCCCHHHHHCC
IEVTSVHKTIESINRSDIVILMIDSVYGIEQQDLSIAELAIQKGKAIIIALNKWDMIAKK
EEHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHH
DRSELLKDICNYNKLNFKVPVIEVSALKNINCNKIIETSIELYKCLTMRISTSVLNKWLK
HHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVEYHKPPLCNGKVVKIKYITQVKVIPPTFIAVVNGSYSIDLTYRQYLMSSLRKHFSID
HHHHHCCCCCCCCEEEEEEEEEEEEECCCEEEEEECCCEEEEHHHHHHHHHHHHHHCCCC
GIPIRLNFKKNKNPYDDSYSKS
CEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA