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The map label for this gene is nuoG [H]

Identifier: 88657707

GI number: 88657707

Start: 623672

End: 625723

Strand: Reverse

Name: nuoG [H]

Synonym: ECH_0618

Alternate gene names: 88657707

Gene position: 625723-623672 (Counterclockwise)

Preceding gene: 88658358

Following gene: 88658474

Centisome position: 53.2

GC content: 32.36

Gene sequence:

>2052_bases
GTGGTTAAACTAGTTATAGATTCTTTAGAAATAGAAGTCGAAGATGGAATGACTGTACTGCAGGCTTGTGAAGTTGCTGG
AGTACAGATACCTAGGTTTTGTTATCATGAAAGGCTTGCTATAGCAGGTAATTGCAGGATGTGTCTAGTGGAAGTTGTTG
GTGGTCCACCTAAACCTGTAGCTTCTTGTGCAATGCCTGTTGCAGAGGGTATGGTAGTAAAGACTAATACTGACAAAATA
AAAAAAGCTAGGGAAGGGGTACTGGAATTTTTATTAATTAATCATCCTTTAGATTGTCCAATTTGTGATCAAGGTGGAGA
ATGTGATTTACAAGACCAAACCATGTTATATGGTAGAGGTAAAAGCAGATATAAGGAAGAGAAACGAGCTGTAAAGAAGA
AGAATTTTGGTCCACTGATAGAAAATACAATGACTAGATGTATACATTGTACTAGATGTGTTAGATTTTTATCAGATGTT
GCTGGTAGCTATGAATTAGGTACAATGGGCCGTGGTGAAAATATGGAGATAGATACGTATATTTCTAAATGTATTACTTC
AGAATTATCTGGTAATATAATAGATCTTTGTCCAGTTGGTGCATTAACTTCAAAACCTTATGCATTTAAAGCTAGATCTT
GGGAATTACGTCATTGTGAAACAATAGATGTATTAGATGCTGTATGTAGTAATATTAGGGTTGATACACGTGGTCTAGAG
GTAATGAGGATATTGCCTAGATTGAATGAAAGTATAAATGAAGAATGGATATCAGATAAAACACGTTTTTCGTATGATGG
TTTAAAATTGCAGAGGTTGGATAAACCATATGTGAGAAAGAATGGGCAGTTATTACCTGCAACATGGGAAGAAGCATTTA
ATGTAATTGCTAAAAGGATTAGTAATGTTTCTGGAGATAAAATTGCGGCAATTGCTGGAGATTTAGCAGATTGTGAATCT
ATGTTGCTATTAAAGGAACTAATGCATGGGTTAGGGAGTTCTAATATAGAATGTAGGCAAGATGGATCAGTAGTACCTAC
TAATAGCAGAGCTTTATATTTGTTTAATACTGGTATATCTAATATAGAAAATGCGGATTTGTGTTTATTAATCAACACAA
ATATAAGGTTTGAAGCGCCTATAATTAATGCAAGATTGCGTAAAAGGTATTTACGAGGAGGATTTAAGATTGCTAATTTA
GGTGTCTATGATAATTTTAATTATAAAGTAGAAGATTTAGGGAATAGTTGTTTGGTATTAGATGATATTCTACATGAAAA
AATACCTTTTTCTGAACTGTTAAAATATGCAAAAAATCCTATGTTAATAATAGGACAAGATGCTTTGGTTGGTGATAATG
GTCATTCTATATTTGTATTAGCTACTAAAATTGCAGCAAAATTTGGTATGTTAAGAGATGATTGGAATGGATTTAATGTT
TTGCATAAAGCTTCTGCTAGAGTAGGTGCTTTAGATATTGGGTTTGTTCCTAGTTCTAACACTAATATAATGTCTGATAT
AATTAATGGTATAGGTTCTAGTGAAATAGAGGTTTTATATTTGTTAGGTGCAGATGAAGTAGAAATTTCTCGTTCTAAGT
CTTCTTTCATTATATATCAAGGACATCATGGAGATAGGGGAGCACAGGTTGCAGATGTGATATTACCTGGTGCAGCATAT
ACTGAAAAAAATGCGACTTATGTTAATACTGAAGGTAGAGTACAGAGAACAAATATTGCTGTTTCTCCTCCTGGTCTTGC
AAGAGAAGATTGGTTAATTATTAAAGAATTATCAAAATATTTAAAAATGGATATGCAATACGAAAGTTTAAATTGCATTA
GAAATAAATTGTCAACATTAGGAAAGCAATTTCGTGAAGAAAATATTGGAAGCTTAATTTCTAATAAATGGGCTTCAATT
GATGGAAGTATGATTTTAGAAAGGGATAGTGTATTTATTAATAAAGATTTTAATTTTTATATGGCAAATCCAATTAGTCG
TGCATCTATTATAATGGCAAATTGTGTAAAAGCTTTTGCAAATAAAGATTAG

Upstream 100 bases:

>100_bases
AGCAGGTAAAATTTTTATTGCAGGTCAATATGATAATGGTGATTTAGTACAAGATACTACAGGTAATCCTATAGAATGGG
CTAGTATATAAGGATAGTGC

Downstream 100 bases:

>100_bases
GTGAGTATGAGTTATTATAATATTTTTTTGGATTTTTTAAGTTACATAGGTAGTGGAGCTGCATTATTTATAAAAATAAT
TGCAGTGATAATATCGGTTA

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MVKLVIDSLEIEVEDGMTVLQACEVAGVQIPRFCYHERLAIAGNCRMCLVEVVGGPPKPVASCAMPVAEGMVVKTNTDKI
KKAREGVLEFLLINHPLDCPICDQGGECDLQDQTMLYGRGKSRYKEEKRAVKKKNFGPLIENTMTRCIHCTRCVRFLSDV
AGSYELGTMGRGENMEIDTYISKCITSELSGNIIDLCPVGALTSKPYAFKARSWELRHCETIDVLDAVCSNIRVDTRGLE
VMRILPRLNESINEEWISDKTRFSYDGLKLQRLDKPYVRKNGQLLPATWEEAFNVIAKRISNVSGDKIAAIAGDLADCES
MLLLKELMHGLGSSNIECRQDGSVVPTNSRALYLFNTGISNIENADLCLLINTNIRFEAPIINARLRKRYLRGGFKIANL
GVYDNFNYKVEDLGNSCLVLDDILHEKIPFSELLKYAKNPMLIIGQDALVGDNGHSIFVLATKIAAKFGMLRDDWNGFNV
LHKASARVGALDIGFVPSSNTNIMSDIINGIGSSEIEVLYLLGADEVEISRSKSSFIIYQGHHGDRGAQVADVILPGAAY
TEKNATYVNTEGRVQRTNIAVSPPGLAREDWLIIKELSKYLKMDMQYESLNCIRNKLSTLGKQFREENIGSLISNKWASI
DGSMILERDSVFINKDFNFYMANPISRASIIMANCVKAFANKD

Sequences:

>Translated_683_residues
MVKLVIDSLEIEVEDGMTVLQACEVAGVQIPRFCYHERLAIAGNCRMCLVEVVGGPPKPVASCAMPVAEGMVVKTNTDKI
KKAREGVLEFLLINHPLDCPICDQGGECDLQDQTMLYGRGKSRYKEEKRAVKKKNFGPLIENTMTRCIHCTRCVRFLSDV
AGSYELGTMGRGENMEIDTYISKCITSELSGNIIDLCPVGALTSKPYAFKARSWELRHCETIDVLDAVCSNIRVDTRGLE
VMRILPRLNESINEEWISDKTRFSYDGLKLQRLDKPYVRKNGQLLPATWEEAFNVIAKRISNVSGDKIAAIAGDLADCES
MLLLKELMHGLGSSNIECRQDGSVVPTNSRALYLFNTGISNIENADLCLLINTNIRFEAPIINARLRKRYLRGGFKIANL
GVYDNFNYKVEDLGNSCLVLDDILHEKIPFSELLKYAKNPMLIIGQDALVGDNGHSIFVLATKIAAKFGMLRDDWNGFNV
LHKASARVGALDIGFVPSSNTNIMSDIINGIGSSEIEVLYLLGADEVEISRSKSSFIIYQGHHGDRGAQVADVILPGAAY
TEKNATYVNTEGRVQRTNIAVSPPGLAREDWLIIKELSKYLKMDMQYESLNCIRNKLSTLGKQFREENIGSLISNKWASI
DGSMILERDSVFINKDFNFYMANPISRASIIMANCVKAFANKD
>Mature_683_residues
MVKLVIDSLEIEVEDGMTVLQACEVAGVQIPRFCYHERLAIAGNCRMCLVEVVGGPPKPVASCAMPVAEGMVVKTNTDKI
KKAREGVLEFLLINHPLDCPICDQGGECDLQDQTMLYGRGKSRYKEEKRAVKKKNFGPLIENTMTRCIHCTRCVRFLSDV
AGSYELGTMGRGENMEIDTYISKCITSELSGNIIDLCPVGALTSKPYAFKARSWELRHCETIDVLDAVCSNIRVDTRGLE
VMRILPRLNESINEEWISDKTRFSYDGLKLQRLDKPYVRKNGQLLPATWEEAFNVIAKRISNVSGDKIAAIAGDLADCES
MLLLKELMHGLGSSNIECRQDGSVVPTNSRALYLFNTGISNIENADLCLLINTNIRFEAPIINARLRKRYLRGGFKIANL
GVYDNFNYKVEDLGNSCLVLDDILHEKIPFSELLKYAKNPMLIIGQDALVGDNGHSIFVLATKIAAKFGMLRDDWNGFNV
LHKASARVGALDIGFVPSSNTNIMSDIINGIGSSEIEVLYLLGADEVEISRSKSSFIIYQGHHGDRGAQVADVILPGAAY
TEKNATYVNTEGRVQRTNIAVSPPGLAREDWLIIKELSKYLKMDMQYESLNCIRNKLSTLGKQFREENIGSLISNKWASI
DGSMILERDSVFINKDFNFYMANPISRASIIMANCVKAFANKD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=706, Percent_Identity=51.5580736543909, Blast_Score=706, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=639, Percent_Identity=26.60406885759, Blast_Score=207, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17565758, Length=692, Percent_Identity=47.5433526011561, Blast_Score=642, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566231, Length=585, Percent_Identity=50.5982905982906, Blast_Score=601, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=61.1111111111111, Blast_Score=331, Evalue=8e-91,
Organism=Drosophila melanogaster, GI24640559, Length=691, Percent_Identity=48.3357452966715, Blast_Score=644, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=691, Percent_Identity=48.3357452966715, Blast_Score=644, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 75943; Mature: 75943

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLVIDSLEIEVEDGMTVLQACEVAGVQIPRFCYHERLAIAGNCRMCLVEVVGGPPKPV
CEEEEEEEEEEEECCCHHHHHHHHHCCCCCCHHHHHCCEEEECCCCEEEEEECCCCCCCH
ASCAMPVAEGMVVKTNTDKIKKAREGVLEFLLINHPLDCPICDQGGECDLQDQTMLYGRG
HHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCC
KSRYKEEKRAVKKKNFGPLIENTMTRCIHCTRCVRFLSDVAGSYELGTMGRGENMEIDTY
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHH
ISKCITSELSGNIIDLCPVGALTSKPYAFKARSWELRHCETIDVLDAVCSNIRVDTRGLE
HHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCEECCCHHH
VMRILPRLNESINEEWISDKTRFSYDGLKLQRLDKPYVRKNGQLLPATWEEAFNVIAKRI
HHHHHHHHHHHHHHHHCCCCCCEEECCEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHH
SNVSGDKIAAIAGDLADCESMLLLKELMHGLGSSNIECRQDGSVVPTNSRALYLFNTGIS
CCCCCCEEEEHHCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCEECCCCCEEEEEECCCC
NIENADLCLLINTNIRFEAPIINARLRKRYLRGGFKIANLGVYDNFNYKVEDLGNSCLVL
CCCCCCEEEEEECCEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCEEHHHCCCCEEEE
DDILHEKIPFSELLKYAKNPMLIIGQDALVGDNGHSIFVLATKIAAKFGMLRDDWNGFNV
HHHHHCCCCHHHHHHHCCCCEEEEECCEEECCCCCEEEEEHHHHHHHHCCCCCCCCCHHH
LHKASARVGALDIGFVPSSNTNIMSDIINGIGSSEIEVLYLLGADEVEISRSKSSFIIYQ
HHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCEEEEE
GHHGDRGAQVADVILPGAAYTEKNATYVNTEGRVQRTNIAVSPPGLAREDWLIIKELSKY
CCCCCCCCEEEHEEECCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
LKMDMQYESLNCIRNKLSTLGKQFREENIGSLISNKWASIDGSMILERDSVFINKDFNFY
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCEE
MANPISRASIIMANCVKAFANKD
ECCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVKLVIDSLEIEVEDGMTVLQACEVAGVQIPRFCYHERLAIAGNCRMCLVEVVGGPPKPV
CEEEEEEEEEEEECCCHHHHHHHHHCCCCCCHHHHHCCEEEECCCCEEEEEECCCCCCCH
ASCAMPVAEGMVVKTNTDKIKKAREGVLEFLLINHPLDCPICDQGGECDLQDQTMLYGRG
HHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCC
KSRYKEEKRAVKKKNFGPLIENTMTRCIHCTRCVRFLSDVAGSYELGTMGRGENMEIDTY
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHH
ISKCITSELSGNIIDLCPVGALTSKPYAFKARSWELRHCETIDVLDAVCSNIRVDTRGLE
HHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCEECCCHHH
VMRILPRLNESINEEWISDKTRFSYDGLKLQRLDKPYVRKNGQLLPATWEEAFNVIAKRI
HHHHHHHHHHHHHHHHCCCCCCEEECCEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHH
SNVSGDKIAAIAGDLADCESMLLLKELMHGLGSSNIECRQDGSVVPTNSRALYLFNTGIS
CCCCCCEEEEHHCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCEECCCCCEEEEEECCCC
NIENADLCLLINTNIRFEAPIINARLRKRYLRGGFKIANLGVYDNFNYKVEDLGNSCLVL
CCCCCCEEEEEECCEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCEEHHHCCCCEEEE
DDILHEKIPFSELLKYAKNPMLIIGQDALVGDNGHSIFVLATKIAAKFGMLRDDWNGFNV
HHHHHCCCCHHHHHHHCCCCEEEEECCEEECCCCCEEEEEHHHHHHHHCCCCCCCCCHHH
LHKASARVGALDIGFVPSSNTNIMSDIINGIGSSEIEVLYLLGADEVEISRSKSSFIIYQ
HHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCEEEEE
GHHGDRGAQVADVILPGAAYTEKNATYVNTEGRVQRTNIAVSPPGLAREDWLIIKELSKY
CCCCCCCCEEEHEEECCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
LKMDMQYESLNCIRNKLSTLGKQFREENIGSLISNKWASIDGSMILERDSVFINKDFNFY
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCEE
MANPISRASIIMANCVKAFANKD
ECCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA