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The map label for this gene is nuoH [H]

Identifier: 88658474

GI number: 88658474

Start: 622562

End: 623665

Strand: Reverse

Name: nuoH [H]

Synonym: ECH_0617

Alternate gene names: 88658474

Gene position: 623665-622562 (Counterclockwise)

Preceding gene: 88657707

Following gene: 88658000

Centisome position: 53.02

GC content: 31.43

Gene sequence:

>1104_bases
ATGAGTTATTATAATATTTTTTTGGATTTTTTAAGTTACATAGGTAGTGGAGCTGCATTATTTATAAAAATAATTGCAGT
GATAATATCGGTTATGATATCTGTTGCTTATTTAGTGTACATGGAGCGTAAGGTTATTGCGGCAATACAGTTGAGGCAAG
GTCCTAATGTTGTTGGACCATTTGGTTTATTGCAACCTTTTGCTGACGCTGTAAAGCTTATTATTAAGGAACATATTATT
CCTTTTAAATCAAATAAAATATGTTTTTTGATTGCTCCGATTATTACTTTTACTTTAGCTTTGTTAGGGTGGGCTGTCAT
TCCATTTGGAGCTGATGTAATTGTTAATGATGGATATGAAGTGATAATACCTAATGCTATTGCAAATATAAATATTGGTG
TACTATATATTTTAGCTATTTCTTCTCTTGGAGTTTATGGAATTATAATAGCTGGATGGTCAAGTAACTCAAATTATGCT
TTTTTAGGTGCAATTAGGTCTGCATCACAAATGATATCATATGAAGTATCTATAGGTTTAACTATAGTTACAGTGTTATT
AGCAACTGGATCATTAAAATTAGGTGAGATAGTTGTAGCACGGCATAATATGCCTTACTGGATAGATTTATTATTATTGC
CAATGGCATGTATTTTTTTTATTTCAGCTTTAGCTGAGACTAATAGACATCCTTTCGATCTACCAGAAGCAGAATCAGAG
TTAGTATCTGGATATAATGTTGAATACTCATCTATGCCATTTGCATTGTTTTTTTTAGGAGAATATGCAAATATGATATT
AATTAATGCAATGGCAGTAATATTTTTCTTTGGTGGGTGGTATCCACCTTTAAATATTGGCTTCTTATATATAATTCCTG
GGATTGTATGGTTTGTATTGAAAGTGGTAGCATTGTTATTTTGCTTTATATGGATTCGTGCTACTATCCCTAGGTACCGT
TATGATCAGCTAATGGGGTTAGGATGGAAAGTATTTTTACCTATATCTTTGCTATGGGTAGTATTAGTTTCGAGTATTCT
AGTATATACAGATTCATTGCCTAGTAATAATAAGCAATATGTATCACATGCTATGCATAAATAG

Upstream 100 bases:

>100_bases
TAATAAAGATTTTAATTTTTATATGGCAAATCCAATTAGTCGTGCATCTATTATAATGGCAAATTGTGTAAAAGCTTTTG
CAAATAAAGATTAGGTGAGT

Downstream 100 bases:

>100_bases
ACTTTATTGGAAGATGATATTTTAATGTGTTTACTTCATTTATTTTTTCATACTAAGGTAGTTTTTTATTAATACATTTT
GTTATAAGTGTCGTGTTTAT

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSYYNIFLDFLSYIGSGAALFIKIIAVIISVMISVAYLVYMERKVIAAIQLRQGPNVVGPFGLLQPFADAVKLIIKEHII
PFKSNKICFLIAPIITFTLALLGWAVIPFGADVIVNDGYEVIIPNAIANINIGVLYILAISSLGVYGIIIAGWSSNSNYA
FLGAIRSASQMISYEVSIGLTIVTVLLATGSLKLGEIVVARHNMPYWIDLLLLPMACIFFISALAETNRHPFDLPEAESE
LVSGYNVEYSSMPFALFFLGEYANMILINAMAVIFFFGGWYPPLNIGFLYIIPGIVWFVLKVVALLFCFIWIRATIPRYR
YDQLMGLGWKVFLPISLLWVVLVSSILVYTDSLPSNNKQYVSHAMHK

Sequences:

>Translated_367_residues
MSYYNIFLDFLSYIGSGAALFIKIIAVIISVMISVAYLVYMERKVIAAIQLRQGPNVVGPFGLLQPFADAVKLIIKEHII
PFKSNKICFLIAPIITFTLALLGWAVIPFGADVIVNDGYEVIIPNAIANINIGVLYILAISSLGVYGIIIAGWSSNSNYA
FLGAIRSASQMISYEVSIGLTIVTVLLATGSLKLGEIVVARHNMPYWIDLLLLPMACIFFISALAETNRHPFDLPEAESE
LVSGYNVEYSSMPFALFFLGEYANMILINAMAVIFFFGGWYPPLNIGFLYIIPGIVWFVLKVVALLFCFIWIRATIPRYR
YDQLMGLGWKVFLPISLLWVVLVSSILVYTDSLPSNNKQYVSHAMHK
>Mature_366_residues
SYYNIFLDFLSYIGSGAALFIKIIAVIISVMISVAYLVYMERKVIAAIQLRQGPNVVGPFGLLQPFADAVKLIIKEHIIP
FKSNKICFLIAPIITFTLALLGWAVIPFGADVIVNDGYEVIIPNAIANINIGVLYILAISSLGVYGIIIAGWSSNSNYAF
LGAIRSASQMISYEVSIGLTIVTVLLATGSLKLGEIVVARHNMPYWIDLLLLPMACIFFISALAETNRHPFDLPEAESEL
VSGYNVEYSSMPFALFFLGEYANMILINAMAVIFFFGGWYPPLNIGFLYIIPGIVWFVLKVVALLFCFIWIRATIPRYRY
DQLMGLGWKVFLPISLLWVVLVSSILVYTDSLPSNNKQYVSHAMHK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=324, Percent_Identity=44.7530864197531, Blast_Score=268, Evalue=7e-72,
Organism=Escherichia coli, GI1788618, Length=329, Percent_Identity=38.9057750759878, Blast_Score=245, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 40812; Mature: 40681

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYYNIFLDFLSYIGSGAALFIKIIAVIISVMISVAYLVYMERKVIAAIQLRQGPNVVGP
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FGLLQPFADAVKLIIKEHIIPFKSNKICFLIAPIITFTLALLGWAVIPFGADVIVNDGYE
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCE
VIIPNAIANINIGVLYILAISSLGVYGIIIAGWSSNSNYAFLGAIRSASQMISYEVSIGL
EEECCCCCCCCHHHHHHHHHHHCCEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHH
TIVTVLLATGSLKLGEIVVARHNMPYWIDLLLLPMACIFFISALAETNRHPFDLPEAESE
HHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LVSGYNVEYSSMPFALFFLGEYANMILINAMAVIFFFGGWYPPLNIGFLYIIPGIVWFVL
HHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KVVALLFCFIWIRATIPRYRYDQLMGLGWKVFLPISLLWVVLVSSILVYTDSLPSNNKQY
HHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VSHAMHK
HHHHHCC
>Mature Secondary Structure 
SYYNIFLDFLSYIGSGAALFIKIIAVIISVMISVAYLVYMERKVIAAIQLRQGPNVVGP
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FGLLQPFADAVKLIIKEHIIPFKSNKICFLIAPIITFTLALLGWAVIPFGADVIVNDGYE
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCE
VIIPNAIANINIGVLYILAISSLGVYGIIIAGWSSNSNYAFLGAIRSASQMISYEVSIGL
EEECCCCCCCCHHHHHHHHHHHCCEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHH
TIVTVLLATGSLKLGEIVVARHNMPYWIDLLLLPMACIFFISALAETNRHPFDLPEAESE
HHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LVSGYNVEYSSMPFALFFLGEYANMILINAMAVIFFFGGWYPPLNIGFLYIIPGIVWFVL
HHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KVVALLFCFIWIRATIPRYRYDQLMGLGWKVFLPISLLWVVLVSSILVYTDSLPSNNKQY
HHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VSHAMHK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA