Click here to switch to the map view.

The map label for this gene is sodB

Identifier: 88608810

GI number: 88608810

Start: 746226

End: 746843

Strand: Reverse

Name: sodB

Synonym: NSE_0843

Alternate gene names: 88608810

Gene position: 746843-746226 (Counterclockwise)

Preceding gene: 88608064

Following gene: 88608351

Centisome position: 86.94

GC content: 41.75

Gene sequence:

>618_bases
ATGACAGTTATACTGCCGAGTCTGCCTTATCACAAAGATGCCCTGGAGCCACTCATCTCCGAGAAGACTTTGAGCTTTCA
TTATGACAAGCATCATTCGGGTTATGTGAATAAGCTAAATGAGTTGTTGGTCAAAAGTGAGTTCAGTCATGGGTACGGGT
TAGTTGATATCATACGAAAAAGTTATGGAAGAGAAGGTTGTGAGGGAATTTTTAACAATGCTGCACAAGTTTGGAATCAC
TCATTTTACTGGAATTCCATGTGCTCTCCATCGTATAGACCTCAACCAGACGATGCTTTTATGAAACAGGTGATACGGGA
TTTTGGCAGTCTTGACATACTAAAGGAGCAGCTTGGTCTTGCTGCTATAAGTCAATTTGGTAGCGGATGGGCGTGGGTAG
TTTTTGATAAGTTCAAAAACAAGCTTGCGATTCTCAAAACGTCCAATGCTGAAACACCATTAACTGTGGAGGGCTTGTCT
CCATTGCTCGTGATTGATGTGTGGGAGCATGCTTATTACCTAGATTATCAGAATCGTAGGCCCGATTATGTAGCAGCATT
TTTAGGTCAGTTGCTTAATTGGGAGTTTGCTTCCGCAAATTATGCTGCATCCATATAA

Upstream 100 bases:

>100_bases
CACAGACTCGGATCATCTACTTCATCGCACATTGTGCTAAGTTTTGCAAAATATGTTTCGAAGTGGTAGTATCCTGCTTT
GTTGATTGATGATATCTGCA

Downstream 100 bases:

>100_bases
GTGTGCAGCTTCTCTTTTTCTTGTAGAGTTGTTTTATGGTTCGAAGGGAAGATTATGAACATCTGACCGAGTCTGAGCTC
GGTTCTCGCCCGCCTAAGGG

Product: superoxide dismutase, Fe

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTVILPSLPYHKDALEPLISEKTLSFHYDKHHSGYVNKLNELLVKSEFSHGYGLVDIIRKSYGREGCEGIFNNAAQVWNH
SFYWNSMCSPSYRPQPDDAFMKQVIRDFGSLDILKEQLGLAAISQFGSGWAWVVFDKFKNKLAILKTSNAETPLTVEGLS
PLLVIDVWEHAYYLDYQNRRPDYVAAFLGQLLNWEFASANYAASI

Sequences:

>Translated_205_residues
MTVILPSLPYHKDALEPLISEKTLSFHYDKHHSGYVNKLNELLVKSEFSHGYGLVDIIRKSYGREGCEGIFNNAAQVWNH
SFYWNSMCSPSYRPQPDDAFMKQVIRDFGSLDILKEQLGLAAISQFGSGWAWVVFDKFKNKLAILKTSNAETPLTVEGLS
PLLVIDVWEHAYYLDYQNRRPDYVAAFLGQLLNWEFASANYAASI
>Mature_204_residues
TVILPSLPYHKDALEPLISEKTLSFHYDKHHSGYVNKLNELLVKSEFSHGYGLVDIIRKSYGREGCEGIFNNAAQVWNHS
FYWNSMCSPSYRPQPDDAFMKQVIRDFGSLDILKEQLGLAAISQFGSGWAWVVFDKFKNKLAILKTSNAETPLTVEGLSP
LLVIDVWEHAYYLDYQNRRPDYVAAFLGQLLNWEFASANYAASI

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=206, Percent_Identity=38.3495145631068, Blast_Score=140, Evalue=7e-34,
Organism=Homo sapiens, GI67782305, Length=206, Percent_Identity=38.3495145631068, Blast_Score=140, Evalue=7e-34,
Organism=Homo sapiens, GI67782309, Length=200, Percent_Identity=34, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI1787946, Length=203, Percent_Identity=50.2463054187192, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1790342, Length=211, Percent_Identity=40.7582938388626, Blast_Score=143, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17569479, Length=202, Percent_Identity=38.1188118811881, Blast_Score=126, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17506561, Length=204, Percent_Identity=35.2941176470588, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6321796, Length=213, Percent_Identity=34.2723004694836, Blast_Score=97, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17136812, Length=204, Percent_Identity=35.7843137254902, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 23392; Mature: 23261

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVILPSLPYHKDALEPLISEKTLSFHYDKHHSGYVNKLNELLVKSEFSHGYGLVDIIRK
CEEEECCCCCCHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
SYGREGCEGIFNNAAQVWNHSFYWNSMCSPSYRPQPDDAFMKQVIRDFGSLDILKEQLGL
HHCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
AAISQFGSGWAWVVFDKFKNKLAILKTSNAETPLTVEGLSPLLVIDVWEHAYYLDYQNRR
HHHHHCCCCEEEEEEHHCCCCEEEEEECCCCCCEEECCCCCEEEEEEHHHEEEECCCCCC
PDYVAAFLGQLLNWEFASANYAASI
CHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TVILPSLPYHKDALEPLISEKTLSFHYDKHHSGYVNKLNELLVKSEFSHGYGLVDIIRK
EEEECCCCCCHHHHHHHHHCCHHEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
SYGREGCEGIFNNAAQVWNHSFYWNSMCSPSYRPQPDDAFMKQVIRDFGSLDILKEQLGL
HHCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
AAISQFGSGWAWVVFDKFKNKLAILKTSNAETPLTVEGLSPLLVIDVWEHAYYLDYQNRR
HHHHHCCCCEEEEEEHHCCCCEEEEEECCCCCCEEECCCCCEEEEEEHHHEEEECCCCCC
PDYVAAFLGQLLNWEFASANYAASI
CHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]