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The map label for this gene is era

Identifier: 88608771

GI number: 88608771

Start: 845304

End: 846230

Strand: Reverse

Name: era

Synonym: NSE_0959

Alternate gene names: 88608771

Gene position: 846230-845304 (Counterclockwise)

Preceding gene: 88608410

Following gene: 88608796

Centisome position: 98.51

GC content: 39.7

Gene sequence:

>927_bases
ATGAGTAGTCCCGAGTATAATAGCAGCGATTGCCTGCAGACTGGAGAAAATTTTAGTACTCGCTCCGCTTTTGTTTCTCT
CATTGGGAACAGTAATGTTGGCAAGTCCACATTGTTGAATGCCCTTATTGGAAGCAAGATATCTGCGGTTACACATAAAG
TACAGACCACAAGAACGAGAATCAGAGGTATATACACAAAAGATGATGTTCAATTGGTTTTCGTTGATACTCCTGGAATT
TTTATTCCGCGATGTCAGCTCGAAAGGGTCATAGTGAAAAACGCCTGGAGAGCATTCGCTGGAACAGATATTTTTTGTTT
TATAATTGATCCAAGGCGCCCTATCTCGGACAGTACAAAGGATATACTCAGGAAAGCTAATGGCAAGTTGGTACTGGTAA
TAAACAAAATAGATCTTGTGGAAAAACCAAGGCTGCTAGAAGTTGCTCAAGAACTAAACAGCTTGGGCCATTTTGAGAAG
ACATTCATGATTTCGGCTCTCAAAGGTAATGGAGTTGCTGACCTTATGAACTACCTTCTTAAATCTGCTCAACCGGGACC
CTGGTATTTTGATAAAGAAGATGAAACCGATATGCCGCTTGGCTTTAATCTTTCTGAAATTCTCCGGGAAAAGTTGTTTA
TCAGACTACATCAGGAACTTCCTTACTCACTGACCGTAGAAACCGAAAATATTGAAATCCTTGATAGGAGCGTGAAGATC
AGACAAGTACTCCACGTAATGAGTGAATCGCATAAAATGATCGTAATAGGTTCGTGTGGAAAAACAATTGGTACGATCAG
AAAATCCGCTGAGAGAGAAATGGCAAATCTTTTTTCTGGGAGAAAAGTGTACTTGTCAATATTTGTAAGGGTGAGTCCAA
ACTGGGGGGAAAAATCTGATATTTTAAATACGATAAATTACATCTAG

Upstream 100 bases:

>100_bases
TGATCTAGACAGAATTATTGCTACAATTGGATGAGCTAAGTCGGAGATCTACCGATTTGCATGTATTCTGTTATGAAAGT
CCCCTTTTCAAAAAGTCTCA

Downstream 100 bases:

>100_bases
CCAGATCTAGCCGATAAAACAAAGCTTTCATGAATTTCAGCGGTTTCCAGTTATCTCGTAATCTCTGCCTTCTGCTCTAT
GTACAAAACTGAAGAATAAA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSSPEYNSSDCLQTGENFSTRSAFVSLIGNSNVGKSTLLNALIGSKISAVTHKVQTTRTRIRGIYTKDDVQLVFVDTPGI
FIPRCQLERVIVKNAWRAFAGTDIFCFIIDPRRPISDSTKDILRKANGKLVLVINKIDLVEKPRLLEVAQELNSLGHFEK
TFMISALKGNGVADLMNYLLKSAQPGPWYFDKEDETDMPLGFNLSEILREKLFIRLHQELPYSLTVETENIEILDRSVKI
RQVLHVMSESHKMIVIGSCGKTIGTIRKSAEREMANLFSGRKVYLSIFVRVSPNWGEKSDILNTINYI

Sequences:

>Translated_308_residues
MSSPEYNSSDCLQTGENFSTRSAFVSLIGNSNVGKSTLLNALIGSKISAVTHKVQTTRTRIRGIYTKDDVQLVFVDTPGI
FIPRCQLERVIVKNAWRAFAGTDIFCFIIDPRRPISDSTKDILRKANGKLVLVINKIDLVEKPRLLEVAQELNSLGHFEK
TFMISALKGNGVADLMNYLLKSAQPGPWYFDKEDETDMPLGFNLSEILREKLFIRLHQELPYSLTVETENIEILDRSVKI
RQVLHVMSESHKMIVIGSCGKTIGTIRKSAEREMANLFSGRKVYLSIFVRVSPNWGEKSDILNTINYI
>Mature_307_residues
SSPEYNSSDCLQTGENFSTRSAFVSLIGNSNVGKSTLLNALIGSKISAVTHKVQTTRTRIRGIYTKDDVQLVFVDTPGIF
IPRCQLERVIVKNAWRAFAGTDIFCFIIDPRRPISDSTKDILRKANGKLVLVINKIDLVEKPRLLEVAQELNSLGHFEKT
FMISALKGNGVADLMNYLLKSAQPGPWYFDKEDETDMPLGFNLSEILREKLFIRLHQELPYSLTVETENIEILDRSVKIR
QVLHVMSESHKMIVIGSCGKTIGTIRKSAEREMANLFSGRKVYLSIFVRVSPNWGEKSDILNTINYI

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=314, Percent_Identity=30.8917197452229, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1788919, Length=291, Percent_Identity=35.0515463917526, Blast_Score=150, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24646434, Length=310, Percent_Identity=30.9677419354839, Blast_Score=118, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34761; Mature: 34630

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPEYNSSDCLQTGENFSTRSAFVSLIGNSNVGKSTLLNALIGSKISAVTHKVQTTRTR
CCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
IRGIYTKDDVQLVFVDTPGIFIPRCQLERVIVKNAWRAFAGTDIFCFIIDPRRPISDSTK
HHEEEEECCEEEEEEECCCEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
DILRKANGKLVLVINKIDLVEKPRLLEVAQELNSLGHFEKTFMISALKGNGVADLMNYLL
HHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHEEEEECCCCHHHHHHHHH
KSAQPGPWYFDKEDETDMPLGFNLSEILREKLFIRLHQELPYSLTVETENIEILDRSVKI
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHH
RQVLHVMSESHKMIVIGSCGKTIGTIRKSAEREMANLFSGRKVYLSIFVRVSPNWGEKSD
HHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHH
ILNTINYI
HHHHHCCC
>Mature Secondary Structure 
SSPEYNSSDCLQTGENFSTRSAFVSLIGNSNVGKSTLLNALIGSKISAVTHKVQTTRTR
CCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
IRGIYTKDDVQLVFVDTPGIFIPRCQLERVIVKNAWRAFAGTDIFCFIIDPRRPISDSTK
HHEEEEECCEEEEEEECCCEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
DILRKANGKLVLVINKIDLVEKPRLLEVAQELNSLGHFEKTFMISALKGNGVADLMNYLL
HHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHEEEEECCCCHHHHHHHHH
KSAQPGPWYFDKEDETDMPLGFNLSEILREKLFIRLHQELPYSLTVETENIEILDRSVKI
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHH
RQVLHVMSESHKMIVIGSCGKTIGTIRKSAEREMANLFSGRKVYLSIFVRVSPNWGEKSD
HHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHH
ILNTINYI
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]