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The map label for this gene is xerD

Identifier: 88608752

GI number: 88608752

Start: 115865

End: 116782

Strand: Direct

Name: xerD

Synonym: NSE_0144

Alternate gene names: 88608752

Gene position: 115865-116782 (Clockwise)

Preceding gene: 88608029

Following gene: 88608726

Centisome position: 13.49

GC content: 41.07

Gene sequence:

>918_bases
ATGCAAGCGAGTGATTGCAAATATGTGGAACAGTTTCTGGAAAAGATCCTGGTTGAGAGAAATGCCACACTTAACACGAT
CAGCAGCTATCGGACCGATCTTAGATTGTTAAGCACCTTTCTCAAAAAAAGGGGTCTAAAAGATGCATCAAAAGAGAATT
TATATGAATACATCGCCAACTTGCGAGCTCAACAGCTCTCCAATGCAACAATACGAAGGAAAATAGCGACTTTTAGACAA
TTTTTCTCATTCTTATACTCCGAAAAAATCTCCAGTACCAATCCAGCTCAAAGTCTTGAGCTTCCCAAAAAGACGTTAGT
ACTGCCTAGGTACCTGACCAAAGAAGAAGTTTTCTCCTTACTTACTTTCTTAGAAGCAGGGCAGCCTGCAACCCTACGAT
TGTATGCAATCCTGGAGATCTTATATTCCTCTGGTATGCGGGTCTCCGAACTTATAAACATGAAAGTTTCCGACATACGA
CCGCTTCTTAATGGGCAGCAGCATATCATCATTGTTGGGAAGGGTAGAAAGGAGAGAATATTGCCATTCTCTAAGAAAGC
AATACAAGTGCTCAAGCTGTATCTAACTTCCTACCAAAGCAATTCCCCTTGGCTTTTTCCGGGGGCAGGGAGAAAAGATA
GACCAATGTCAAGACAAAGGTTAGGACAGCTCCTGAAAGAACTTGCACTAAAGTGCAAAATCGATCCCAAACGAATTTCT
CCACATGTTATCCGCCACTCGTTTGCAACACACCTACTGGATAATGGAATGGACATTAAGGTTGTACAAGATTTACTAGG
ACATGCACAGATTACAACCACTCAAATTTATACCCACATTTCACAACACAAGCTCCATAAGGAAATTGAAGCAAAGCATC
CACTCTCCTCAAAAGAAATCGGAAAAACACCTTTTTAA

Upstream 100 bases:

>100_bases
AGGCATTTGAAATTTTCTTTGTTAGGTACTGTCTTGTCCTGGAGCTTTTCACAGAAAAAGTGCGGCAACCTAATTATACG
ATTCACTATGGGATTGGTGT

Downstream 100 bases:

>100_bases
GTGGAAACAAATACATCAACTGCTCAATGTATTTACACCAGGGGCTAACACATCGTTAAATATGAATGGTTCATACTTGA
ATTTAAATAGTCTTGAATAT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MQASDCKYVEQFLEKILVERNATLNTISSYRTDLRLLSTFLKKRGLKDASKENLYEYIANLRAQQLSNATIRRKIATFRQ
FFSFLYSEKISSTNPAQSLELPKKTLVLPRYLTKEEVFSLLTFLEAGQPATLRLYAILEILYSSGMRVSELINMKVSDIR
PLLNGQQHIIIVGKGRKERILPFSKKAIQVLKLYLTSYQSNSPWLFPGAGRKDRPMSRQRLGQLLKELALKCKIDPKRIS
PHVIRHSFATHLLDNGMDIKVVQDLLGHAQITTTQIYTHISQHKLHKEIEAKHPLSSKEIGKTPF

Sequences:

>Translated_305_residues
MQASDCKYVEQFLEKILVERNATLNTISSYRTDLRLLSTFLKKRGLKDASKENLYEYIANLRAQQLSNATIRRKIATFRQ
FFSFLYSEKISSTNPAQSLELPKKTLVLPRYLTKEEVFSLLTFLEAGQPATLRLYAILEILYSSGMRVSELINMKVSDIR
PLLNGQQHIIIVGKGRKERILPFSKKAIQVLKLYLTSYQSNSPWLFPGAGRKDRPMSRQRLGQLLKELALKCKIDPKRIS
PHVIRHSFATHLLDNGMDIKVVQDLLGHAQITTTQIYTHISQHKLHKEIEAKHPLSSKEIGKTPF
>Mature_305_residues
MQASDCKYVEQFLEKILVERNATLNTISSYRTDLRLLSTFLKKRGLKDASKENLYEYIANLRAQQLSNATIRRKIATFRQ
FFSFLYSEKISSTNPAQSLELPKKTLVLPRYLTKEEVFSLLTFLEAGQPATLRLYAILEILYSSGMRVSELINMKVSDIR
PLLNGQQHIIIVGKGRKERILPFSKKAIQVLKLYLTSYQSNSPWLFPGAGRKDRPMSRQRLGQLLKELALKCKIDPKRIS
PHVIRHSFATHLLDNGMDIKVVQDLLGHAQITTTQIYTHISQHKLHKEIEAKHPLSSKEIGKTPF

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=302, Percent_Identity=36.4238410596026, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=30.1369863013699, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1790767, Length=174, Percent_Identity=31.6091954022989, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35037; Mature: 35037

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQASDCKYVEQFLEKILVERNATLNTISSYRTDLRLLSTFLKKRGLKDASKENLYEYIAN
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRAQQLSNATIRRKIATFRQFFSFLYSEKISSTNPAQSLELPKKTLVLPRYLTKEEVFSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCHHHCHHHHHHH
LTFLEAGQPATLRLYAILEILYSSGMRVSELINMKVSDIRPLLNGQQHIIIVGKGRKERI
HHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHCCCEEEEEEECCCCCCC
LPFSKKAIQVLKLYLTSYQSNSPWLFPGAGRKDRPMSRQRLGQLLKELALKCKIDPKRIS
CCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCC
PHVIRHSFATHLLDNGMDIKVVQDLLGHAQITTTQIYTHISQHKLHKEIEAKHPLSSKEI
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GKTPF
CCCCC
>Mature Secondary Structure
MQASDCKYVEQFLEKILVERNATLNTISSYRTDLRLLSTFLKKRGLKDASKENLYEYIAN
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRAQQLSNATIRRKIATFRQFFSFLYSEKISSTNPAQSLELPKKTLVLPRYLTKEEVFSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCHHHCHHHHHHH
LTFLEAGQPATLRLYAILEILYSSGMRVSELINMKVSDIRPLLNGQQHIIIVGKGRKERI
HHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHCCCEEEEEEECCCCCCC
LPFSKKAIQVLKLYLTSYQSNSPWLFPGAGRKDRPMSRQRLGQLLKELALKCKIDPKRIS
CCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCC
PHVIRHSFATHLLDNGMDIKVVQDLLGHAQITTTQIYTHISQHKLHKEIEAKHPLSSKEI
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GKTPF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]