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The map label for this gene is secA

Identifier: 88608684

GI number: 88608684

Start: 196288

End: 198702

Strand: Reverse

Name: secA

Synonym: NSE_0232

Alternate gene names: 88608684

Gene position: 198702-196288 (Counterclockwise)

Preceding gene: 88608847

Following gene: 88608558

Centisome position: 23.13

GC content: 40.54

Gene sequence:

>2415_bases
ATGCTAGATTTAGTGCACAAGATTTTTGACTCTCGCAATCGAAAGATCAAGAGAAAGCTGAAAGACGGTTTGGAGCAAGT
CAATAGTCTTGAGACTAGGATTCGTGACCTCTCAAGTGATGAGCTTAGAAATAAAACTAGTGAATTCAAAGAAAGATTGT
TCAAGCAAAGTGCTTCACTAGATGAAATACTACCTGAAGCATATGCGTGCGTCAGAGAAGCTTCACTCAGGACGCTAGGT
ATGCGGCATTTCGACGTGCAAATCATGGGAGGAATAGTACTGCACTGGGGAATGATAAGTGAAATGCACACAGGTGAAGG
TAAAACGCTTGTAGCAACTTTGGCAGCTTATTTGAATGCTCTATCTGAAAAAGGTGTACATGTGGTCACAGTAAACGACT
ACCTAGCTCGAAGAGATACAGAGTGGATGAAACAGATATACAGACATCTAGGGCTACAAGTTTCTTGTATTACCTCTGAT
ATGCGCGATCCGGAAAGAGCACACGCATACAAAGCAGATATCACTTACGCCACAAACAACGAGCTAGGCTTCGATTATCT
TCGGGATAATATGAAGTTTTCCAAAGGAGAAATGGTTCAGCGGGACCTTCATTATGCGATCGTGGATGAGGTTGACTCAA
TATTGATCGATGAAGCACGTACACCACTCATAATCTCCGGTGTGACAGATAATGCCTCATACCTGTATGCAAGCATGAAC
AAGCTTGCAGAAAAACTCGACAGTACCTTGTATATAGTTGATGAAAAAACAAGAACCGTTTCTCTTACAGAGGAAGGACA
AGAAGCTATAGAAAAGCTGCTAATGGCCGAAAAATTTATAGAGAGTGGTTCATCTCTCTACGAACCACAAAATCTTCAAC
TTGTACATTGTTTGAATCAATCTTTGAAGGCAATTAATCTCTTCCAAAAGAACAAGGACTACATAGTTCAAGACGGTCAA
ATAGTTTTAATAGATGAGTTCACAGGCCGTATGATGCACGGGAGACGGTACTCAGAAGGGCTACATCAGGCACTTGAAGC
CAAAGAAAATCTCAAGATCCAAAATGAGAATCAAACCCTTGCATCTATCACATTCCAAAACTACTTCAGGATGTATGGCA
AGCTTTCGGGCATGACAGGAACAGCTGCAACAGAAAGAGAAGAATTCTCGACAATATATGGACTAGAAGTTGTACAAATA
CCATCACATCTGCCAGTACGCAGAGTCGATCACGATGATGAAATATACGCTTCAAAAAAGGAGAAATACGAAGCTATCCT
AGCACTTGCAAAAGAATGTCATGAGAAACTACAACCCATCCTGATTGGAACAACGAGTATAGAAAATTCCGAAGAACTTT
CACGTGAACTAAAAAAGGCAAAGCTAAAGCACTCCGTACTGAATGCGAAACAGCACGCTTTTGAAGCGGAAATTATTGCA
CAAGCTGGCAAGCCCGGAGCTATAACTATAGCCACAAATATGGCCGGAAGAGGAACAGATATCCAGTTAGGCGGCAACAT
CAATTTTAACATTTCAGCAAACGATGAAGCCGAAAAAGAGCACGCAAAGAACGAAGAGATAGTTCGAAAAGCTGGAGGAC
TCTACGTTATCGGTACCGAAAGACATGAAAGCCGTCGTATTGATAATCAACTCAGAGGAAGATCGGGTAGACAAGGTGAT
CCAGGTGAATCAAAATTTTTTCTCTCACTCGATGATGATCTATTACGTGTATTCGGTACATCAGGGATACGCAACATGCT
AAAAAAACAGCTTTCCAATAACGGTGCCATAAAACATTCTTACATAACCCGATCTTTGGAAAAGGCTCAAAAGAAAGTAG
AGAGCCGAAATTATGAGATCAGAAAAAACCTTATTAAGTTCGATGATGTGATAAATGAACAGAGGAAGGTCATCTTCAGC
CAGCGGAACAACATCATGGAGAGTGGTGATATAGATCTCTTACCAATAGTGACAGAGGTGAATGCCAAAACTCTTGAGAA
TGCGCGATCTAAGAATTTTTATGATATCTCAACTCTGATCCACAGTATGCAATCGATATACAACGAGGACTTCAAGGAGT
TACACAAAACCGAAGATATTGATGGCTTTATAGACTCAAAAACAAAAAGCATCATTGCAGAAAAAGAGCGCGCACATGTG
GAATTTCTTTTGGAAATAAAAAAACGCATAATGATAGCGATACTGGATCAACTATGGAAAGAGCATTTGCAATTTCTAGA
GAATCTTAGATTAAGTATAAACCTAAAGGCCGTTGCCCAAAAAAACCCACTTATCGAATTTAAACATGAGGCATTCCAGG
CTTTCCAAAGGCTCTCAGAGCGGTGGCATGAAAATATCATAGCGTCTTTCGTCCGCGTAAAACTTGTTGAACGGATGCAT
ATGAAAGTCATGTAG

Upstream 100 bases:

>100_bases
GAAACAAAAGCAAAAGACGTACTGCTTGGTCACATATTTGCTAATCTCTAAACAAGAGCATAGAATATTGACCTGTATGT
GGTAACATTCTTCAGGCAAG

Downstream 100 bases:

>100_bases
TATCTATTTATAGACCCTTTCTTTAGGTTTTCCTAATTTTATTAGGAAATATCCCATATTTGGGCAGGTTATCTTGACTA
ATCGATGGTTCTATTGGTAT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 804; Mature: 804

Protein sequence:

>804_residues
MLDLVHKIFDSRNRKIKRKLKDGLEQVNSLETRIRDLSSDELRNKTSEFKERLFKQSASLDEILPEAYACVREASLRTLG
MRHFDVQIMGGIVLHWGMISEMHTGEGKTLVATLAAYLNALSEKGVHVVTVNDYLARRDTEWMKQIYRHLGLQVSCITSD
MRDPERAHAYKADITYATNNELGFDYLRDNMKFSKGEMVQRDLHYAIVDEVDSILIDEARTPLIISGVTDNASYLYASMN
KLAEKLDSTLYIVDEKTRTVSLTEEGQEAIEKLLMAEKFIESGSSLYEPQNLQLVHCLNQSLKAINLFQKNKDYIVQDGQ
IVLIDEFTGRMMHGRRYSEGLHQALEAKENLKIQNENQTLASITFQNYFRMYGKLSGMTGTAATEREEFSTIYGLEVVQI
PSHLPVRRVDHDDEIYASKKEKYEAILALAKECHEKLQPILIGTTSIENSEELSRELKKAKLKHSVLNAKQHAFEAEIIA
QAGKPGAITIATNMAGRGTDIQLGGNINFNISANDEAEKEHAKNEEIVRKAGGLYVIGTERHESRRIDNQLRGRSGRQGD
PGESKFFLSLDDDLLRVFGTSGIRNMLKKQLSNNGAIKHSYITRSLEKAQKKVESRNYEIRKNLIKFDDVINEQRKVIFS
QRNNIMESGDIDLLPIVTEVNAKTLENARSKNFYDISTLIHSMQSIYNEDFKELHKTEDIDGFIDSKTKSIIAEKERAHV
EFLLEIKKRIMIAILDQLWKEHLQFLENLRLSINLKAVAQKNPLIEFKHEAFQAFQRLSERWHENIIASFVRVKLVERMH
MKVM

Sequences:

>Translated_804_residues
MLDLVHKIFDSRNRKIKRKLKDGLEQVNSLETRIRDLSSDELRNKTSEFKERLFKQSASLDEILPEAYACVREASLRTLG
MRHFDVQIMGGIVLHWGMISEMHTGEGKTLVATLAAYLNALSEKGVHVVTVNDYLARRDTEWMKQIYRHLGLQVSCITSD
MRDPERAHAYKADITYATNNELGFDYLRDNMKFSKGEMVQRDLHYAIVDEVDSILIDEARTPLIISGVTDNASYLYASMN
KLAEKLDSTLYIVDEKTRTVSLTEEGQEAIEKLLMAEKFIESGSSLYEPQNLQLVHCLNQSLKAINLFQKNKDYIVQDGQ
IVLIDEFTGRMMHGRRYSEGLHQALEAKENLKIQNENQTLASITFQNYFRMYGKLSGMTGTAATEREEFSTIYGLEVVQI
PSHLPVRRVDHDDEIYASKKEKYEAILALAKECHEKLQPILIGTTSIENSEELSRELKKAKLKHSVLNAKQHAFEAEIIA
QAGKPGAITIATNMAGRGTDIQLGGNINFNISANDEAEKEHAKNEEIVRKAGGLYVIGTERHESRRIDNQLRGRSGRQGD
PGESKFFLSLDDDLLRVFGTSGIRNMLKKQLSNNGAIKHSYITRSLEKAQKKVESRNYEIRKNLIKFDDVINEQRKVIFS
QRNNIMESGDIDLLPIVTEVNAKTLENARSKNFYDISTLIHSMQSIYNEDFKELHKTEDIDGFIDSKTKSIIAEKERAHV
EFLLEIKKRIMIAILDQLWKEHLQFLENLRLSINLKAVAQKNPLIEFKHEAFQAFQRLSERWHENIIASFVRVKLVERMH
MKVM
>Mature_804_residues
MLDLVHKIFDSRNRKIKRKLKDGLEQVNSLETRIRDLSSDELRNKTSEFKERLFKQSASLDEILPEAYACVREASLRTLG
MRHFDVQIMGGIVLHWGMISEMHTGEGKTLVATLAAYLNALSEKGVHVVTVNDYLARRDTEWMKQIYRHLGLQVSCITSD
MRDPERAHAYKADITYATNNELGFDYLRDNMKFSKGEMVQRDLHYAIVDEVDSILIDEARTPLIISGVTDNASYLYASMN
KLAEKLDSTLYIVDEKTRTVSLTEEGQEAIEKLLMAEKFIESGSSLYEPQNLQLVHCLNQSLKAINLFQKNKDYIVQDGQ
IVLIDEFTGRMMHGRRYSEGLHQALEAKENLKIQNENQTLASITFQNYFRMYGKLSGMTGTAATEREEFSTIYGLEVVQI
PSHLPVRRVDHDDEIYASKKEKYEAILALAKECHEKLQPILIGTTSIENSEELSRELKKAKLKHSVLNAKQHAFEAEIIA
QAGKPGAITIATNMAGRGTDIQLGGNINFNISANDEAEKEHAKNEEIVRKAGGLYVIGTERHESRRIDNQLRGRSGRQGD
PGESKFFLSLDDDLLRVFGTSGIRNMLKKQLSNNGAIKHSYITRSLEKAQKKVESRNYEIRKNLIKFDDVINEQRKVIFS
QRNNIMESGDIDLLPIVTEVNAKTLENARSKNFYDISTLIHSMQSIYNEDFKELHKTEDIDGFIDSKTKSIIAEKERAHV
EFLLEIKKRIMIAILDQLWKEHLQFLENLRLSINLKAVAQKNPLIEFKHEAFQAFQRLSERWHENIIASFVRVKLVERMH
MKVM

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=832, Percent_Identity=49.1586538461538, Blast_Score=761, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_NEOSM (Q2GEH0)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506126.1
- ProteinModelPortal:   Q2GEH0
- SMR:   Q2GEH0
- STRING:   Q2GEH0
- GeneID:   3931784
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0232
- TIGR:   NSE_0232
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   EANIPHE
- ProtClustDB:   CLSK2528079
- BioCyc:   NSEN222891:NSE_0232-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 92194; Mature: 92194

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLVHKIFDSRNRKIKRKLKDGLEQVNSLETRIRDLSSDELRNKTSEFKERLFKQSASL
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
DEILPEAYACVREASLRTLGMRHFDVQIMGGIVLHWGMISEMHTGEGKTLVATLAAYLNA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LSEKGVHVVTVNDYLARRDTEWMKQIYRHLGLQVSCITSDMRDPERAHAYKADITYATNN
HHHCCCEEEEECHHHHHCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHEEEEEEEECCC
ELGFDYLRDNMKFSKGEMVQRDLHYAIVDEVDSILIDEARTPLIISGVTDNASYLYASMN
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
KLAEKLDSTLYIVDEKTRTVSLTEEGQEAIEKLLMAEKFIESGSSLYEPQNLQLVHCLNQ
HHHHHHCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SLKAINLFQKNKDYIVQDGQIVLIDEFTGRMMHGRRYSEGLHQALEAKENLKIQNENQTL
HHHHHHHHHCCCCEEEECCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHCCEEECCCCCH
ASITFQNYFRMYGKLSGMTGTAATEREEFSTIYGLEVVQIPSHLPVRRVDHDDEIYASKK
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHH
EKYEAILALAKECHEKLQPILIGTTSIENSEELSRELKKAKLKHSVLNAKQHAFEAEIIA
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAGKPGAITIATNMAGRGTDIQLGGNINFNISANDEAEKEHAKNEEIVRKAGGLYVIGTE
HCCCCCEEEEEECCCCCCCEEEECCEEEEEECCCCHHHHHHCCCHHHHHHCCCEEEEECC
RHESRRIDNQLRGRSGRQGDPGESKFFLSLDDDLLRVFGTSGIRNMLKKQLSNNGAIKHS
CHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHCCHHHHHHHHHHHCCCCCEEHH
YITRSLEKAQKKVESRNYEIRKNLIKFDDVINEQRKVIFSQRNNIMESGDIDLLPIVTEV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECC
NAKTLENARSKNFYDISTLIHSMQSIYNEDFKELHKTEDIDGFIDSKTKSIIAEKERAHV
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EFLLEIKKRIMIAILDQLWKEHLQFLENLRLSINLKAVAQKNPLIEFKHEAFQAFQRLSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
RWHENIIASFVRVKLVERMHMKVM
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDLVHKIFDSRNRKIKRKLKDGLEQVNSLETRIRDLSSDELRNKTSEFKERLFKQSASL
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
DEILPEAYACVREASLRTLGMRHFDVQIMGGIVLHWGMISEMHTGEGKTLVATLAAYLNA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LSEKGVHVVTVNDYLARRDTEWMKQIYRHLGLQVSCITSDMRDPERAHAYKADITYATNN
HHHCCCEEEEECHHHHHCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHEEEEEEEECCC
ELGFDYLRDNMKFSKGEMVQRDLHYAIVDEVDSILIDEARTPLIISGVTDNASYLYASMN
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
KLAEKLDSTLYIVDEKTRTVSLTEEGQEAIEKLLMAEKFIESGSSLYEPQNLQLVHCLNQ
HHHHHHCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SLKAINLFQKNKDYIVQDGQIVLIDEFTGRMMHGRRYSEGLHQALEAKENLKIQNENQTL
HHHHHHHHHCCCCEEEECCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHCCEEECCCCCH
ASITFQNYFRMYGKLSGMTGTAATEREEFSTIYGLEVVQIPSHLPVRRVDHDDEIYASKK
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHH
EKYEAILALAKECHEKLQPILIGTTSIENSEELSRELKKAKLKHSVLNAKQHAFEAEIIA
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAGKPGAITIATNMAGRGTDIQLGGNINFNISANDEAEKEHAKNEEIVRKAGGLYVIGTE
HCCCCCEEEEEECCCCCCCEEEECCEEEEEECCCCHHHHHHCCCHHHHHHCCCEEEEECC
RHESRRIDNQLRGRSGRQGDPGESKFFLSLDDDLLRVFGTSGIRNMLKKQLSNNGAIKHS
CHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHCCHHHHHHHHHHHCCCCCEEHH
YITRSLEKAQKKVESRNYEIRKNLIKFDDVINEQRKVIFSQRNNIMESGDIDLLPIVTEV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECC
NAKTLENARSKNFYDISTLIHSMQSIYNEDFKELHKTEDIDGFIDSKTKSIIAEKERAHV
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EFLLEIKKRIMIAILDQLWKEHLQFLENLRLSINLKAVAQKNPLIEFKHEAFQAFQRLSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
RWHENIIASFVRVKLVERMHMKVM
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA