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The map label for this gene is tldD

Identifier: 88608439

GI number: 88608439

Start: 189556

End: 190989

Strand: Direct

Name: tldD

Synonym: NSE_0224

Alternate gene names: 88608439

Gene position: 189556-190989 (Clockwise)

Preceding gene: 88608549

Following gene: 88608367

Centisome position: 22.07

GC content: 44.7

Gene sequence:

>1434_bases
GTGAGGTCGGAAGTTCAAGTCTTCTCAAGCCCACCGTTTTATATGTTAGATCTCGAAAAATTTATTCCCGTTGTTGTATC
AGCTCTTCAGGGTGCTGATGGAGGAGAGCTGTTTGTCGAGTATTCTCTTTCAGAGATTCTGAAGTTCGAGGATGGCGTAC
TTGCTGAGAGTAATTATGCCGATTCTTCTGGATTTGGTCTCCGTGCGTTTTATGGTGATAAGGTGCTCTATACGCACTCC
TCACACTTGAGCGACGCTAGTATCTTTGAAGCTAGTGATTTTATTCGGAAAAACCGTCTGGCAGATGGCTCAGCTATGAC
TGCAGAGGCTGCGCATGAGACCGCTTGTGGAGATCCTCTTTATAAATTTGAAATCCAAGATGATTCCTTCTCGTTTGAGA
GGAAGGTTGCTTTTCTGCGTCAGGTTTACGACTATGCTTTATCAAAGAGCGTAAACATAGCTAGTGCTTCTGTTACTCTT
ATGCGGTTTGTCCGAAGAATTGGAATCATTAAAAATACCGGAGGAACCGTAACTGACGAACAGCCAATGGTGCGCTTAGG
GTTTTCAGTCGTGTTAAAGAATGAGAAAGGTGGAGCTCAAGGGGGCACTTCAGGCAAAGGGGGGAGATTCGCGCTTTCTG
AGTTAATGAAAGACTGGTACGTGGTTGTTGATCGTGCATTTCACAAAGCTGAGGTTGCTTTGCGGGCTGTGCCTTGCCCC
TCTGGTGAGATGACAGTGGTTTTAGGGAGTGGATGGCCAGGTGTCTTGTTACACGAAGCTATAGGTCATGGGCTAGAAGC
TGATTTTAATCGTAAAGGGGTTTCCGCTTTTTCCGGTCTGATTGGTAAGAAGGTTGCTTCTGATGTTGTCAGTGTTGTCG
ATAACGGTAGGATCAATGAAGCTAGGGGTTCCATTAATGTTGATGATGAAGGTACACGATCTTCATATAATGTTCTGATA
AAGGACGGGATCCTCCAGGGTTACATGTTTGACCTCATGAACGCTAGGTTGATGGGTGAACAGTCTACTGGTAATGGGCG
TCGCGAGAGCTATATGAACATTCCGCTGCCACGCATGACAAATACGTATATGTTGCCTGGTGATAAAACTCCGGATGAAA
TAATAAAGAGTATTAAAAGCGGTATTTACGCTGTCGATTTCTCGGGGGGTCAGGTTGATATAACATCTGGAAAATTTGTA
TTTTCAGCATCTGAAGCATACTTAATAGAGGATGGTGAGGTTACAGTACCAGTAAAAGAGGTTACACTTATCGGGGATGG
TCCAACTATATTGAAAAGGATTTCAGCTGTTGGAAATGATCTCAAGCTCGACGACGGGGTAGGTACTTGTGGTAAAGATG
GGCAGTCTGTGCCTGTGTGTGTTGGTCAGCCGACCATTTGTGTGGATAAAATTACTGTTGGTGGGACTGCTTAA

Upstream 100 bases:

>100_bases
TTTGTTTCTGTATATAGCTTGTGCTACAATTTGCGGCGCCTGGCTGTTTTGAGGAATGTGGGCTTGTAGCTCAGCTGGTT
AGAGTACACGCCTGATAAGC

Downstream 100 bases:

>100_bases
ATTTCCTGTTTATCCTATCTTCTAAGCTTTTCTTACTATATTCCCTCATGTTACAATCCGGGGTCTTCGGTGTTTTTGGA
GAGCTGTATGGACGCTGCAG

Product: TldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MRSEVQVFSSPPFYMLDLEKFIPVVVSALQGADGGELFVEYSLSEILKFEDGVLAESNYADSSGFGLRAFYGDKVLYTHS
SHLSDASIFEASDFIRKNRLADGSAMTAEAAHETACGDPLYKFEIQDDSFSFERKVAFLRQVYDYALSKSVNIASASVTL
MRFVRRIGIIKNTGGTVTDEQPMVRLGFSVVLKNEKGGAQGGTSGKGGRFALSELMKDWYVVVDRAFHKAEVALRAVPCP
SGEMTVVLGSGWPGVLLHEAIGHGLEADFNRKGVSAFSGLIGKKVASDVVSVVDNGRINEARGSINVDDEGTRSSYNVLI
KDGILQGYMFDLMNARLMGEQSTGNGRRESYMNIPLPRMTNTYMLPGDKTPDEIIKSIKSGIYAVDFSGGQVDITSGKFV
FSASEAYLIEDGEVTVPVKEVTLIGDGPTILKRISAVGNDLKLDDGVGTCGKDGQSVPVCVGQPTICVDKITVGGTA

Sequences:

>Translated_477_residues
MRSEVQVFSSPPFYMLDLEKFIPVVVSALQGADGGELFVEYSLSEILKFEDGVLAESNYADSSGFGLRAFYGDKVLYTHS
SHLSDASIFEASDFIRKNRLADGSAMTAEAAHETACGDPLYKFEIQDDSFSFERKVAFLRQVYDYALSKSVNIASASVTL
MRFVRRIGIIKNTGGTVTDEQPMVRLGFSVVLKNEKGGAQGGTSGKGGRFALSELMKDWYVVVDRAFHKAEVALRAVPCP
SGEMTVVLGSGWPGVLLHEAIGHGLEADFNRKGVSAFSGLIGKKVASDVVSVVDNGRINEARGSINVDDEGTRSSYNVLI
KDGILQGYMFDLMNARLMGEQSTGNGRRESYMNIPLPRMTNTYMLPGDKTPDEIIKSIKSGIYAVDFSGGQVDITSGKFV
FSASEAYLIEDGEVTVPVKEVTLIGDGPTILKRISAVGNDLKLDDGVGTCGKDGQSVPVCVGQPTICVDKITVGGTA
>Mature_477_residues
MRSEVQVFSSPPFYMLDLEKFIPVVVSALQGADGGELFVEYSLSEILKFEDGVLAESNYADSSGFGLRAFYGDKVLYTHS
SHLSDASIFEASDFIRKNRLADGSAMTAEAAHETACGDPLYKFEIQDDSFSFERKVAFLRQVYDYALSKSVNIASASVTL
MRFVRRIGIIKNTGGTVTDEQPMVRLGFSVVLKNEKGGAQGGTSGKGGRFALSELMKDWYVVVDRAFHKAEVALRAVPCP
SGEMTVVLGSGWPGVLLHEAIGHGLEADFNRKGVSAFSGLIGKKVASDVVSVVDNGRINEARGSINVDDEGTRSSYNVLI
KDGILQGYMFDLMNARLMGEQSTGNGRRESYMNIPLPRMTNTYMLPGDKTPDEIIKSIKSGIYAVDFSGGQVDITSGKFV
FSASEAYLIEDGEVTVPVKEVTLIGDGPTILKRISAVGNDLKLDDGVGTCGKDGQSVPVCVGQPTICVDKITVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=454, Percent_Identity=48.2378854625551, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1790682, Length=172, Percent_Identity=24.4186046511628, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51322; Mature: 51322

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSEVQVFSSPPFYMLDLEKFIPVVVSALQGADGGELFVEYSLSEILKFEDGVLAESNYA
CCCCEEEECCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHCCCCEECCCCC
DSSGFGLRAFYGDKVLYTHSSHLSDASIFEASDFIRKNRLADGSAMTAEAAHETACGDPL
CCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCE
YKFEIQDDSFSFERKVAFLRQVYDYALSKSVNIASASVTLMRFVRRIGIIKNTGGTVTDE
EEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEECCCCCCCCC
QPMVRLGFSVVLKNEKGGAQGGTSGKGGRFALSELMKDWYVVVDRAFHKAEVALRAVPCP
CCCEEECEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCC
SGEMTVVLGSGWPGVLLHEAIGHGLEADFNRKGVSAFSGLIGKKVASDVVSVVDNGRINE
CCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEC
ARGSINVDDEGTRSSYNVLIKDGILQGYMFDLMNARLMGEQSTGNGRRESYMNIPLPRMT
CCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHEECCCCCCCCCCCCEECCCCCCCC
NTYMLPGDKTPDEIIKSIKSGIYAVDFSGGQVDITSGKFVFSASEAYLIEDGEVTVPVKE
CCEECCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEECCCEEEEEEE
VTLIGDGPTILKRISAVGNDLKLDDGVGTCGKDGQSVPVCVGQPTICVDKITVGGTA
EEEECCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCC
>Mature Secondary Structure
MRSEVQVFSSPPFYMLDLEKFIPVVVSALQGADGGELFVEYSLSEILKFEDGVLAESNYA
CCCCEEEECCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHCCCCEECCCCC
DSSGFGLRAFYGDKVLYTHSSHLSDASIFEASDFIRKNRLADGSAMTAEAAHETACGDPL
CCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCE
YKFEIQDDSFSFERKVAFLRQVYDYALSKSVNIASASVTLMRFVRRIGIIKNTGGTVTDE
EEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEECCCCCCCCC
QPMVRLGFSVVLKNEKGGAQGGTSGKGGRFALSELMKDWYVVVDRAFHKAEVALRAVPCP
CCCEEECEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCC
SGEMTVVLGSGWPGVLLHEAIGHGLEADFNRKGVSAFSGLIGKKVASDVVSVVDNGRINE
CCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEC
ARGSINVDDEGTRSSYNVLIKDGILQGYMFDLMNARLMGEQSTGNGRRESYMNIPLPRMT
CCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHEECCCCCCCCCCCCEECCCCCCCC
NTYMLPGDKTPDEIIKSIKSGIYAVDFSGGQVDITSGKFVFSASEAYLIEDGEVTVPVKE
CCEECCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEECCCEEEEEEE
VTLIGDGPTILKRISAVGNDLKLDDGVGTCGKDGQSVPVCVGQPTICVDKITVGGTA
EEEECCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]