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The map label for this gene is efp

Identifier: 88608413

GI number: 88608413

Start: 166629

End: 167204

Strand: Reverse

Name: efp

Synonym: NSE_0196

Alternate gene names: 88608413

Gene position: 167204-166629 (Counterclockwise)

Preceding gene: 88608056

Following gene: 88608592

Centisome position: 19.46

GC content: 42.19

Gene sequence:

>576_bases
GTGTCACAGAAAATCCTTGGAAATGACATCAGGGTAGGCAATGTTCTAGAGTACAAGAATTCTCTGTACCAGGTTTTGAA
ACGGGAGCACGTAAAACCTGGCAAGGGTGGTGCCTTTGTCAATGTCGAAATGAAGAGCATAGATGGAGCAAGCAAAGTTA
ATCACAGGTTTAGGTCTGATGAGGTTGTTTTTAAGGCTTTCCTAGAAGAAGATGAGTGTCACTACCTTTTCAAAGAGGGA
GATGCCATCGTTCTGATGAGCCTTTCGACTTATGAGCAGTTTTCCGTTGATGCCGATCTTTTTGTAGATGTAGACAAGTA
TTTGAAAGAAGAGGTCGTTGTAAAACTTCTTAGGCACGGCGATAAAATTGTTGGTGTGAAAGTGCAAGATAACCTGGCGT
ACACGGTTGAGGAAACTGAACCTTATATAAAGGGTCAAACTGTTACGTCATCCTACAAACCTGCTATATTGAACGGTGGG
TTGCTGAAGGTTATGGTACCCCCGTTTATCAAGGTTGGGGATCAAATCGTTGTTAAAACAGAAGATGGAACATATGTTGG
GAGGACCGAAAAATGA

Upstream 100 bases:

>100_bases
ATAACTGTACATTTCCCGATGCCTGGACTGTGGTTCAGGCAATTGAAAGTCCGTGCGATGTGAGTTACAATGTCAGCCTG
TTTTCTTGTACTTGTTCGCC

Downstream 100 bases:

>100_bases
CACATGGAATGTTTTTTTTTCAGATTGATGATAATGGTTTGCTAGACGTCGTTGATCTTACGAATTGTGGGTGTGCTATA
CCAATTCTTGAGCAGTTCTC

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSQKILGNDIRVGNVLEYKNSLYQVLKREHVKPGKGGAFVNVEMKSIDGASKVNHRFRSDEVVFKAFLEEDECHYLFKEG
DAIVLMSLSTYEQFSVDADLFVDVDKYLKEEVVVKLLRHGDKIVGVKVQDNLAYTVEETEPYIKGQTVTSSYKPAILNGG
LLKVMVPPFIKVGDQIVVKTEDGTYVGRTEK

Sequences:

>Translated_191_residues
MSQKILGNDIRVGNVLEYKNSLYQVLKREHVKPGKGGAFVNVEMKSIDGASKVNHRFRSDEVVFKAFLEEDECHYLFKEG
DAIVLMSLSTYEQFSVDADLFVDVDKYLKEEVVVKLLRHGDKIVGVKVQDNLAYTVEETEPYIKGQTVTSSYKPAILNGG
LLKVMVPPFIKVGDQIVVKTEDGTYVGRTEK
>Mature_190_residues
SQKILGNDIRVGNVLEYKNSLYQVLKREHVKPGKGGAFVNVEMKSIDGASKVNHRFRSDEVVFKAFLEEDECHYLFKEGD
AIVLMSLSTYEQFSVDADLFVDVDKYLKEEVVVKLLRHGDKIVGVKVQDNLAYTVEETEPYIKGQTVTSSYKPAILNGGL
LKVMVPPFIKVGDQIVVKTEDGTYVGRTEK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=181, Percent_Identity=30.939226519337, Blast_Score=88, Evalue=3e-19,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 21495; Mature: 21364

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKILGNDIRVGNVLEYKNSLYQVLKREHVKPGKGGAFVNVEMKSIDGASKVNHRFRSD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHCCCC
EVVFKAFLEEDECHYLFKEGDAIVLMSLSTYEQFSVDADLFVDVDKYLKEEVVVKLLRHG
HHHHHHHCCCCCEEEEEECCCEEEEEEECCCHHHCCCCCEEEEHHHHHHHHHHHHHHHCC
DKIVGVKVQDNLAYTVEETEPYIKGQTVTSSYKPAILNGGLLKVMVPPFIKVGDQIVVKT
CEEEEEEEECCEEEEEECCCCEECCCEECCCCCCEEECCCEEEEECCCHHHCCCEEEEEE
EDGTYVGRTEK
CCCEEECCCCC
>Mature Secondary Structure 
SQKILGNDIRVGNVLEYKNSLYQVLKREHVKPGKGGAFVNVEMKSIDGASKVNHRFRSD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHCCCC
EVVFKAFLEEDECHYLFKEGDAIVLMSLSTYEQFSVDADLFVDVDKYLKEEVVVKLLRHG
HHHHHHHCCCCCEEEEEECCCEEEEEEECCCHHHCCCCCEEEEHHHHHHHHHHHHHHHCC
DKIVGVKVQDNLAYTVEETEPYIKGQTVTSSYKPAILNGGLLKVMVPPFIKVGDQIVVKT
CEEEEEEEECCEEEEEECCCCEECCCEECCCCCCEEECCCEEEEECCCHHHCCCEEEEEE
EDGTYVGRTEK
CCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA