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The map label for this gene is plsC [C]

Identifier: 88608386

GI number: 88608386

Start: 330832

End: 331626

Strand: Direct

Name: plsC [C]

Synonym: NSE_0407

Alternate gene names: 88608386

Gene position: 330832-331626 (Clockwise)

Preceding gene: 88608013

Following gene: 88608293

Centisome position: 38.51

GC content: 39.37

Gene sequence:

>795_bases
ATGAATAAAAGTATGAGAAATAACGGTTTCTTTGCTGCAGCAGCATACGTGACGATGAACGTCCTGTTTAATGTTTCTGT
TGTTGCGTGGACTACTTTATACGGCCTAGTCGTGCTACCAGCTCTTTTTTTACCTCCAGAGGATGTAATAGAAGTGCGCA
GGGTTTGGATCAGGGGGGTTTTTGTTCTCCTGAGATTTTTTTTCAATGTTGAATTTGAGATAAGAGGCAGTGAAAATATC
CACCTACACAAACAGTTTATAGTTGCGTCTAAACACCATTCTCCCTTGGATGTGATTTTGTTAGCTGATCTGTTTCAGAA
GCCGGCCTTTGTACTAAAAAGAAGTCTTATCTTTATTCCAATCTTTGGGCTATACATGATTGCAACAAAAATGATTACGG
TTTCCTATTCAGGAAAATCAAACGGTTTGGATGTGTTGAGAAAAATGGTTAGGCAAGCCAAAGTACTTTCTAAAAATAGG
ACAATAATTCTATATCCGGAGGGAGGAAGAACTAAAGTCGGTGAGGAAGTGGGGTACAAAAGAGGTATACTGGCTCTTTA
TAAACATCTCAATCTTCCTGTGCTACCAATCGCATTGAATGTTGGCCAAATTTGGCCAGTGGGCTATTTCAGCAATAAAC
GAAGTGGTAAAGCTGTAGTCCAGATATTGCCCCCAATTATGCCAGGTCTGAAAGACGATGAGTTTCTGCAGGTCCTGCGA
GATGCGATAGAAACTAATACAAAACATCTCTTAAGCAGTGAGAATAAACATCTTCTAACACTACAAAAGAATTAA

Upstream 100 bases:

>100_bases
TTCTTAAGATCTGTTTTCTAATGAGTGTTATTCTGCTGAATGCAGTTTTTGAACGGTTTTCAGGTGGATCTTTTCTGTTG
TTCGTTATGCACTACAAAAA

Downstream 100 bases:

>100_bases
GTGAACAGGTTTCAGCCGCATATTTGGTTATTCCTCTTTGGAGTCTTTTGTATTATCATCAATCTTTACCTTTCAGGAGC
AAAGTAGTACACACTTAGCC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein

Products: CoA +diacyl-sn-glycerol phosphate [C]

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase Family Protein; Acyltransferase; Acyltransferase Domain Protein; N-Acylhomoserine Lactone Synthase; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNKSMRNNGFFAAAAYVTMNVLFNVSVVAWTTLYGLVVLPALFLPPEDVIEVRRVWIRGVFVLLRFFFNVEFEIRGSENI
HLHKQFIVASKHHSPLDVILLADLFQKPAFVLKRSLIFIPIFGLYMIATKMITVSYSGKSNGLDVLRKMVRQAKVLSKNR
TIILYPEGGRTKVGEEVGYKRGILALYKHLNLPVLPIALNVGQIWPVGYFSNKRSGKAVVQILPPIMPGLKDDEFLQVLR
DAIETNTKHLLSSENKHLLTLQKN

Sequences:

>Translated_264_residues
MNKSMRNNGFFAAAAYVTMNVLFNVSVVAWTTLYGLVVLPALFLPPEDVIEVRRVWIRGVFVLLRFFFNVEFEIRGSENI
HLHKQFIVASKHHSPLDVILLADLFQKPAFVLKRSLIFIPIFGLYMIATKMITVSYSGKSNGLDVLRKMVRQAKVLSKNR
TIILYPEGGRTKVGEEVGYKRGILALYKHLNLPVLPIALNVGQIWPVGYFSNKRSGKAVVQILPPIMPGLKDDEFLQVLR
DAIETNTKHLLSSENKHLLTLQKN
>Mature_264_residues
MNKSMRNNGFFAAAAYVTMNVLFNVSVVAWTTLYGLVVLPALFLPPEDVIEVRRVWIRGVFVLLRFFFNVEFEIRGSENI
HLHKQFIVASKHHSPLDVILLADLFQKPAFVLKRSLIFIPIFGLYMIATKMITVSYSGKSNGLDVLRKMVRQAKVLSKNR
TIILYPEGGRTKVGEEVGYKRGILALYKHLNLPVLPIALNVGQIWPVGYFSNKRSGKAVVQILPPIMPGLKDDEFLQVLR
DAIETNTKHLLSSENKHLLTLQKN

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17568319, Length=168, Percent_Identity=26.1904761904762, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320151, Length=204, Percent_Identity=24.5098039215686, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51 [C]

Molecular weight: Translated: 29930; Mature: 29930

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSMRNNGFFAAAAYVTMNVLFNVSVVAWTTLYGLVVLPALFLPPEDVIEVRRVWIRGV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FVLLRFFFNVEFEIRGSENIHLHKQFIVASKHHSPLDVILLADLFQKPAFVLKRSLIFIP
HHHHHHHHCCEEEEECCCCEEEEHEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
IFGLYMIATKMITVSYSGKSNGLDVLRKMVRQAKVLSKNRTIILYPEGGRTKVGEEVGYK
HHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCHH
RGILALYKHLNLPVLPIALNVGQIWPVGYFSNKRSGKAVVQILPPIMPGLKDDEFLQVLR
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHEEHHHHCCCCCCHHHHHHHH
DAIETNTKHLLSSENKHLLTLQKN
HHHHCCHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MNKSMRNNGFFAAAAYVTMNVLFNVSVVAWTTLYGLVVLPALFLPPEDVIEVRRVWIRGV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FVLLRFFFNVEFEIRGSENIHLHKQFIVASKHHSPLDVILLADLFQKPAFVLKRSLIFIP
HHHHHHHHCCEEEEECCCCEEEEHEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
IFGLYMIATKMITVSYSGKSNGLDVLRKMVRQAKVLSKNRTIILYPEGGRTKVGEEVGYK
HHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCHH
RGILALYKHLNLPVLPIALNVGQIWPVGYFSNKRSGKAVVQILPPIMPGLKDDEFLQVLR
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHEEHHHHCCCCCCHHHHHHHH
DAIETNTKHLLSSENKHLLTLQKN
HHHHCCHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acyl-CoA; acyl-sn-glycerol phosphate [C]

Specific reaction: Acyl-CoA + acyl-sn-glycerol phosphate = CoA +diacyl-sn-glycerol phosphate [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA