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The map label for this gene is mrp [H]

Identifier: 88608350

GI number: 88608350

Start: 792519

End: 793259

Strand: Reverse

Name: mrp [H]

Synonym: NSE_0888

Alternate gene names: 88608350

Gene position: 793259-792519 (Counterclockwise)

Preceding gene: 88608254

Following gene: 88608428

Centisome position: 92.35

GC content: 39.68

Gene sequence:

>741_bases
ATGCCAAAAACTATTATTATTGCTTCTGGTAAGGGAGGTGTAGGAAAATCGACGGTCGCGTTAAATCTTGCTGTTTTACT
GGCGCGAAGGTTCAAAACCGGCCTGATAGATGCCGATATCTACGGACCCTCTCTCTCGTTTATGCTAGGAACGAAAACAA
AAATTACAATGACTGAACGAGAAACGTTAGTTCCTGTGGAAAAGTTTGGACTTAAATATGTTTCAGTTGGTGCAATGGCT
GAACCAGGTGCGCCAATACTCTGGCGTGGGCCAATGCTGTCTAAGATTCTACGTACCTTTCTTACCAACACTGAATGGGG
CGAGTTAGATTATCTTGTTATCGATACTCCTCCTGGTACCGGTGATGTTCATATTACACTCTGCAGTGATTTTAATGTTG
ATGGTGCAGTTCTGGTAACAACTGCACAAAGAGTTTCCATACAGGATGTTTCAAGAGCATGTGAAATGTTTAGGAAATTA
AAAATTCTTGTTCTTGGTGTAATTGAGAACATGAGTTGCTCAAATTTATATAAAGACGAGCAGTATATTATTGGAAACGC
AGAAAACACAAGGGAATTTTCAAAAGCTTTTTCTATTCCAGTGCTTGGTAGAGTTCCATTTTTGAGGCAAATCTCATATT
CGTGTGATAATTCTATACCCGCGGTGTTAGACGCTGAAATCACCACGATATACAAACCAATCTTAGACGAATTGCTTCTT
AGGCTAAATGAAAAAGTGTGA

Upstream 100 bases:

>100_bases
GGTATACAATACCATTTGATCTGAACAAAATGTTCCATTTAACAGCCGATACAGAGGATTCTTTAGAGACCTTTTTTATA
GCGGAGTGTTCGGATTTGAT

Downstream 100 bases:

>100_bases
TCAGAATTTGTGAGACAAACTAAAGGGGAATATTCACACGGCAAGGTGTATTTCTTTACTTTTAACTGTGCTTCACTAGA
TTTTGTTATCTATCAGCAAT

Product: ATP-binding Mrp/Nbp35 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MPKTIIIASGKGGVGKSTVALNLAVLLARRFKTGLIDADIYGPSLSFMLGTKTKITMTERETLVPVEKFGLKYVSVGAMA
EPGAPILWRGPMLSKILRTFLTNTEWGELDYLVIDTPPGTGDVHITLCSDFNVDGAVLVTTAQRVSIQDVSRACEMFRKL
KILVLGVIENMSCSNLYKDEQYIIGNAENTREFSKAFSIPVLGRVPFLRQISYSCDNSIPAVLDAEITTIYKPILDELLL
RLNEKV

Sequences:

>Translated_246_residues
MPKTIIIASGKGGVGKSTVALNLAVLLARRFKTGLIDADIYGPSLSFMLGTKTKITMTERETLVPVEKFGLKYVSVGAMA
EPGAPILWRGPMLSKILRTFLTNTEWGELDYLVIDTPPGTGDVHITLCSDFNVDGAVLVTTAQRVSIQDVSRACEMFRKL
KILVLGVIENMSCSNLYKDEQYIIGNAENTREFSKAFSIPVLGRVPFLRQISYSCDNSIPAVLDAEITTIYKPILDELLL
RLNEKV
>Mature_245_residues
PKTIIIASGKGGVGKSTVALNLAVLLARRFKTGLIDADIYGPSLSFMLGTKTKITMTERETLVPVEKFGLKYVSVGAMAE
PGAPILWRGPMLSKILRTFLTNTEWGELDYLVIDTPPGTGDVHITLCSDFNVDGAVLVTTAQRVSIQDVSRACEMFRKLK
ILVLGVIENMSCSNLYKDEQYIIGNAENTREFSKAFSIPVLGRVPFLRQISYSCDNSIPAVLDAEITTIYKPILDELLLR
LNEKV

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=249, Percent_Identity=36.144578313253, Blast_Score=165, Evalue=3e-41,
Organism=Homo sapiens, GI118572611, Length=231, Percent_Identity=37.2294372294372, Blast_Score=151, Evalue=4e-37,
Organism=Homo sapiens, GI6912540, Length=252, Percent_Identity=35.7142857142857, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI87082045, Length=247, Percent_Identity=39.6761133603239, Blast_Score=167, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI25143050, Length=253, Percent_Identity=33.201581027668, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322188, Length=265, Percent_Identity=32.8301886792453, Blast_Score=145, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6321347, Length=222, Percent_Identity=37.8378378378378, Blast_Score=136, Evalue=2e-33,
Organism=Drosophila melanogaster, GI221511043, Length=250, Percent_Identity=35.2, Blast_Score=160, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24667611, Length=242, Percent_Identity=35.9504132231405, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19921440, Length=256, Percent_Identity=33.984375, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR000808 [H]

Pfam domain/function: PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 27064; Mature: 26933

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTIIIASGKGGVGKSTVALNLAVLLARRFKTGLIDADIYGPSLSFMLGTKTKITMTER
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCCEEEEEECC
ETLVPVEKFGLKYVSVGAMAEPGAPILWRGPMLSKILRTFLTNTEWGELDYLVIDTPPGT
CCCCCHHHHCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
GDVHITLCSDFNVDGAVLVTTAQRVSIQDVSRACEMFRKLKILVLGVIENMSCSNLYKDE
CCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCC
QYIIGNAENTREFSKAFSIPVLGRVPFLRQISYSCDNSIPAVLDAEITTIYKPILDELLL
EEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHH
RLNEKV
HHCCCC
>Mature Secondary Structure 
PKTIIIASGKGGVGKSTVALNLAVLLARRFKTGLIDADIYGPSLSFMLGTKTKITMTER
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCCEEEEEECC
ETLVPVEKFGLKYVSVGAMAEPGAPILWRGPMLSKILRTFLTNTEWGELDYLVIDTPPGT
CCCCCHHHHCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
GDVHITLCSDFNVDGAVLVTTAQRVSIQDVSRACEMFRKLKILVLGVIENMSCSNLYKDE
CCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCC
QYIIGNAENTREFSKAFSIPVLGRVPFLRQISYSCDNSIPAVLDAEITTIYKPILDELLL
EEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHH
RLNEKV
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]