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The map label for this gene is nuoC

Identifier: 88608330

GI number: 88608330

Start: 353471

End: 354031

Strand: Direct

Name: nuoC

Synonym: NSE_0432

Alternate gene names: 88608330

Gene position: 353471-354031 (Clockwise)

Preceding gene: 88608136

Following gene: 88608457

Centisome position: 41.15

GC content: 42.25

Gene sequence:

>561_bases
ATGACTATTGACACAACTGAAGTTGATGCTCTAATTAATGCGCCTGGGCGGTGTGTTGTTAATTCTTCGCTGGAGTCTTT
GGTTGAGCTTATCTCCCATCTGTCTTCCTGTGGTTTTGAGCAGCTAACTGATATTTTTGGGATAGACTACCTAGAACGAG
AGAAAAGAATTGAAGTTGTATACCTTTTGCTAGATTTGAAACGTAATAGAAGGTGTTGTGTGAAGGTGTCTGTAGATCCG
GCTTCTGAGAAAGTCCCTACGTGTTGTGGTGTTTTTTCGGTTGCAAATTGGTTTGAAAGGGAGGTATATGATATGTATGG
TGTGGTTTTTGAAGGCCATCCTGACCTCCGTAGGATACTTACCGATTACGAGTTTGAAGGTTTCCCAATGCTGAAAGACT
TTCCTCTTACTGGTTATAAAGAGGTAAGGTACGATCTTGAGTCGAAGGAGGTTGTTTATGAGAAAGTTGATCTTTCTCAG
GATTATAGGTCGTTTGATTCTCTCACTCCGTGGAAAGGAGTAGGTCGTCCAAGTGATCCCTTCGATGGAAGGAAGGAGTA
G

Upstream 100 bases:

>100_bases
TCCGCCTACAGCAGAAGCGCTTTTGTACGGTGTTCTGTGCCTTCAGAAAAAAATAAACCGGCAGAGAAACTTTATCAGGA
GATAAACCGATTTACCGAAT

Downstream 100 bases:

>100_bases
TTATGTGCCCTTGTGGCGGAATGGTAGACGCGGCAGACTCAAAATCTGCTATCCTCGCGGATGTGCTGGTTCAAATCCAG
TCAAGGGTATTTAGAGTTTT

Product: NADH dehydrogenase I subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTIDTTEVDALINAPGRCVVNSSLESLVELISHLSSCGFEQLTDIFGIDYLEREKRIEVVYLLLDLKRNRRCCVKVSVDP
ASEKVPTCCGVFSVANWFEREVYDMYGVVFEGHPDLRRILTDYEFEGFPMLKDFPLTGYKEVRYDLESKEVVYEKVDLSQ
DYRSFDSLTPWKGVGRPSDPFDGRKE

Sequences:

>Translated_186_residues
MTIDTTEVDALINAPGRCVVNSSLESLVELISHLSSCGFEQLTDIFGIDYLEREKRIEVVYLLLDLKRNRRCCVKVSVDP
ASEKVPTCCGVFSVANWFEREVYDMYGVVFEGHPDLRRILTDYEFEGFPMLKDFPLTGYKEVRYDLESKEVVYEKVDLSQ
DYRSFDSLTPWKGVGRPSDPFDGRKE
>Mature_185_residues
TIDTTEVDALINAPGRCVVNSSLESLVELISHLSSCGFEQLTDIFGIDYLEREKRIEVVYLLLDLKRNRRCCVKVSVDPA
SEKVPTCCGVFSVANWFEREVYDMYGVVFEGHPDLRRILTDYEFEGFPMLKDFPLTGYKEVRYDLESKEVVYEKVDLSQD
YRSFDSLTPWKGVGRPSDPFDGRKE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=156, Percent_Identity=44.8717948717949, Blast_Score=147, Evalue=7e-36,
Organism=Escherichia coli, GI145693162, Length=104, Percent_Identity=37.5, Blast_Score=81, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=166, Percent_Identity=48.7951807228916, Blast_Score=148, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI32563621, Length=166, Percent_Identity=48.7951807228916, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24656494, Length=148, Percent_Identity=49.3243243243243, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_NEOSM (Q2GDX8)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506318.1
- ProteinModelPortal:   Q2GDX8
- SMR:   Q2GDX8
- STRING:   Q2GDX8
- GeneID:   3932238
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0432
- TIGR:   NSE_0432
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   CLSK2527850
- BioCyc:   NSEN222891:NSE_0432-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 21434; Mature: 21302

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDTTEVDALINAPGRCVVNSSLESLVELISHLSSCGFEQLTDIFGIDYLEREKRIEVV
CCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
YLLLDLKRNRRCCVKVSVDPASEKVPTCCGVFSVANWFEREVYDMYGVVFEGHPDLRRIL
HEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHH
TDYEFEGFPMLKDFPLTGYKEVRYDLESKEVVYEKVDLSQDYRSFDSLTPWKGVGRPSDP
HHCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCC
FDGRKE
CCCCCC
>Mature Secondary Structure 
TIDTTEVDALINAPGRCVVNSSLESLVELISHLSSCGFEQLTDIFGIDYLEREKRIEVV
CCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHH
YLLLDLKRNRRCCVKVSVDPASEKVPTCCGVFSVANWFEREVYDMYGVVFEGHPDLRRIL
HEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHH
TDYEFEGFPMLKDFPLTGYKEVRYDLESKEVVYEKVDLSQDYRSFDSLTPWKGVGRPSDP
HHCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCC
FDGRKE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA