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The map label for this gene is frr

Identifier: 88608154

GI number: 88608154

Start: 833159

End: 833716

Strand: Reverse

Name: frr

Synonym: NSE_0945

Alternate gene names: 88608154

Gene position: 833716-833159 (Counterclockwise)

Preceding gene: 88608491

Following gene: 88608842

Centisome position: 97.06

GC content: 41.04

Gene sequence:

>558_bases
ATGCTAGAAGATGTAATTAAGGAAACAAATGATAAACTCCGTTCGTCGTACGAGGTGTTTCTCTCTGACTTGAAGGGTAT
TAGGTCAGGGTCTCTTAGCGTGAGTATATTGGATGGCGTAATTGTCTCGACTCACATGGGTAAGCTACGCCTGAATCAAG
TTGCTAGTCTGTCGGTAGTCAATAATAAGATGCTGTCCGTTCAAGTATGGGACAAATCCACAGTCGGTGCTGTAAAAGAT
GCGATTTTGACTTCTAATCTCGGTATGAATCCGATAGTTGAAGGATCAGTCTTACGTTTGCCGGTTCCTGATCTTACGGA
AGAACGTCGTAAGGAGTTGGTTAAAGTTCTCAAAAAGTACGGTGACAGAGCTAAGGTAGCTGTTAGAAATATCAGACGCG
ATGCTATTTCCAGGATAAAGGTTTTGGAAAAGGCGAAGGAGATATCAGAAAATGATATGCACGCTTTGCTCAAGAAGATA
GATAAAATTATTTCTGAAGAAGATGCTAGAATTGATGATGCTGTGAGCAAAAAGGAAACCGACATCTTGAAGGTATGA

Upstream 100 bases:

>100_bases
CGTGGTAATCTTTTCATTGGACAGTGAAATGGCGTTTTACGAGGTGATCAATAAACAGGGCAACTATAGCACCATAGAGG
GTGAATGAGTTTTTTTAGGT

Downstream 100 bases:

>100_bases
TTGGAAAAGAGCTTCCTGTTCATATTGCAATAATAATGGACGGGAACGCGAGATGGGCCAGAGCGAGAGGTCTGTGTAAC
TCCGATGGATACAAGATGGG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLEDVIKETNDKLRSSYEVFLSDLKGIRSGSLSVSILDGVIVSTHMGKLRLNQVASLSVVNNKMLSVQVWDKSTVGAVKD
AILTSNLGMNPIVEGSVLRLPVPDLTEERRKELVKVLKKYGDRAKVAVRNIRRDAISRIKVLEKAKEISENDMHALLKKI
DKIISEEDARIDDAVSKKETDILKV

Sequences:

>Translated_185_residues
MLEDVIKETNDKLRSSYEVFLSDLKGIRSGSLSVSILDGVIVSTHMGKLRLNQVASLSVVNNKMLSVQVWDKSTVGAVKD
AILTSNLGMNPIVEGSVLRLPVPDLTEERRKELVKVLKKYGDRAKVAVRNIRRDAISRIKVLEKAKEISENDMHALLKKI
DKIISEEDARIDDAVSKKETDILKV
>Mature_185_residues
MLEDVIKETNDKLRSSYEVFLSDLKGIRSGSLSVSILDGVIVSTHMGKLRLNQVASLSVVNNKMLSVQVWDKSTVGAVKD
AILTSNLGMNPIVEGSVLRLPVPDLTEERRKELVKVLKKYGDRAKVAVRNIRRDAISRIKVLEKAKEISENDMHALLKKI
DKIISEEDARIDDAVSKKETDILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=188, Percent_Identity=29.7872340425532, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=32, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=37.8378378378378, Blast_Score=134, Evalue=3e-33,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_NEOSM (Q2GCI7)

Other databases:

- EMBL:   CP000237
- RefSeq:   YP_506809.1
- ProteinModelPortal:   Q2GCI7
- SMR:   Q2GCI7
- STRING:   Q2GCI7
- GeneID:   3931454
- GenomeReviews:   CP000237_GR
- KEGG:   nse:NSE_0945
- TIGR:   NSE_0945
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   CLSK2527749
- BioCyc:   NSEN222891:NSE_0945-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20635; Mature: 20635

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEDVIKETNDKLRSSYEVFLSDLKGIRSGSLSVSILDGVIVSTHMGKLRLNQVASLSVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHH
NNKMLSVQVWDKSTVGAVKDAILTSNLGMNPIVEGSVLRLPVPDLTEERRKELVKVLKKY
CCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHH
GDRAKVAVRNIRRDAISRIKVLEKAKEISENDMHALLKKIDKIISEEDARIDDAVSKKET
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
DILKV
HHCCC
>Mature Secondary Structure
MLEDVIKETNDKLRSSYEVFLSDLKGIRSGSLSVSILDGVIVSTHMGKLRLNQVASLSVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHH
NNKMLSVQVWDKSTVGAVKDAILTSNLGMNPIVEGSVLRLPVPDLTEERRKELVKVLKKY
CCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHH
GDRAKVAVRNIRRDAISRIKVLEKAKEISENDMHALLKKIDKIISEEDARIDDAVSKKET
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
DILKV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA