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The map label for this gene is nadA

Identifier: 88607989

GI number: 88607989

Start: 856566

End: 857513

Strand: Direct

Name: nadA

Synonym: NSE_0969

Alternate gene names: 88607989

Gene position: 856566-857513 (Clockwise)

Preceding gene: 88608180

Following gene: NA

Centisome position: 99.72

GC content: 36.5

Gene sequence:

>948_bases
GTGGGCTTCCTTAAAAATCTTGAGAGAGAGATTGTGGAGCTAAAGAAAAAGAAAAATGCTGTAATACTTGCACACTACTA
CCAAGATGATGAATTACAGGATATAGCCGATTTTGTCGGTGATTCTCTTGATTTATCTAAAAAGGCTTCGAATACGGATG
CTGAAATCATTGTTTTCTGTGGAGTGACATTCATGGGTGAAGTTGCAAAGCTGCTAAGCCCAGGAAAAAAAGTTATTGTG
CCAGATATGGCAGCTGGTTGTTCTTTAGAGGATTCCTGCAAAGTTGAACATTTGAAAAAATTTATAAGTCCTGTTGAGAA
CCCGTTTGTTTTGACATATATAAATTCTTCAGTTCATGTTAAGGCAATATCAGATTCAATATGTACCTCGTCTAGTGCTG
AAAAAATAATAAACAGTATACCAAAAGAGAAAAATATCGTTTTTGCTCCGGACAAGTTTTTAGGGAGCTATTTACAGAAA
AGAACAGGCAGAAAAATGAAAATTTGGCAAGGAACCTGCATCGTTCACGAAAGTTTCTCTGAGAAGCATGCTATCTCACT
TAAATTAGAAAATCCAGATGCAAAAGTTGTTGCTCACCCAGAATGTCCTGATGTGCTTATCAAATACGCGGATTTTGTTG
GATCAACATCGCAAATACTTTCATATATAAAAAAATCGGGCTTCCTAAAGTTTATAGTTCTGACTGAGCCTGGAATAATA
CACCAGGCAAAAAAGATTCTTCCACACGGTATTTTTTTTCCAGTGGAATCAGTTAATTCATCTGGGACATGTGCTATGTG
TAACAAGTGTCCCCACATGAGACTAAACACAATGGAGAAGTTGTATCACTGCTTAGACAAGGAAGAACCATCAATAGAAA
TAGATCCATCAATCTTTGATGCTGCAAGATCTGCTGTTGAGAACATGTTTTTTTACCTGAATAAATAG

Upstream 100 bases:

>100_bases
CCGCTTTCCTCAGTGGAAGCAGTATTAGATTTTATAAGAGCTAGGAATTAATAAGTAAATTTGTTACAACTACACCCGTG
TCTCTTGTAATTACCTAAAA

Downstream 100 bases:

>100_bases
AGGACACAAATCCAATGATTTGTGTTTATTGTTTAAATAGATGTGATCTTACATCATTTATTATTTGATGCGGTAAAAAT
TGAGAAAGGTCTCCTCCAAG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MGFLKNLEREIVELKKKKNAVILAHYYQDDELQDIADFVGDSLDLSKKASNTDAEIIVFCGVTFMGEVAKLLSPGKKVIV
PDMAAGCSLEDSCKVEHLKKFISPVENPFVLTYINSSVHVKAISDSICTSSSAEKIINSIPKEKNIVFAPDKFLGSYLQK
RTGRKMKIWQGTCIVHESFSEKHAISLKLENPDAKVVAHPECPDVLIKYADFVGSTSQILSYIKKSGFLKFIVLTEPGII
HQAKKILPHGIFFPVESVNSSGTCAMCNKCPHMRLNTMEKLYHCLDKEEPSIEIDPSIFDAARSAVENMFFYLNK

Sequences:

>Translated_315_residues
MGFLKNLEREIVELKKKKNAVILAHYYQDDELQDIADFVGDSLDLSKKASNTDAEIIVFCGVTFMGEVAKLLSPGKKVIV
PDMAAGCSLEDSCKVEHLKKFISPVENPFVLTYINSSVHVKAISDSICTSSSAEKIINSIPKEKNIVFAPDKFLGSYLQK
RTGRKMKIWQGTCIVHESFSEKHAISLKLENPDAKVVAHPECPDVLIKYADFVGSTSQILSYIKKSGFLKFIVLTEPGII
HQAKKILPHGIFFPVESVNSSGTCAMCNKCPHMRLNTMEKLYHCLDKEEPSIEIDPSIFDAARSAVENMFFYLNK
>Mature_314_residues
GFLKNLEREIVELKKKKNAVILAHYYQDDELQDIADFVGDSLDLSKKASNTDAEIIVFCGVTFMGEVAKLLSPGKKVIVP
DMAAGCSLEDSCKVEHLKKFISPVENPFVLTYINSSVHVKAISDSICTSSSAEKIINSIPKEKNIVFAPDKFLGSYLQKR
TGRKMKIWQGTCIVHESFSEKHAISLKLENPDAKVVAHPECPDVLIKYADFVGSTSQILSYIKKSGFLKFIVLTEPGIIH
QAKKILPHGIFFPVESVNSSGTCAMCNKCPHMRLNTMEKLYHCLDKEEPSIEIDPSIFDAARSAVENMFFYLNK

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=290, Percent_Identity=36.8965517241379, Blast_Score=211, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 35143; Mature: 35012

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFLKNLEREIVELKKKKNAVILAHYYQDDELQDIADFVGDSLDLSKKASNTDAEIIVFC
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
GVTFMGEVAKLLSPGKKVIVPDMAAGCSLEDSCKVEHLKKFISPVENPFVLTYINSSVHV
CHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEE
KAISDSICTSSSAEKIINSIPKEKNIVFAPDKFLGSYLQKRTGRKMKIWQGTCIVHESFS
EEECCHHHCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCCEEEEEECEEEEECCCC
EKHAISLKLENPDAKVVAHPECPDVLIKYADFVGSTSQILSYIKKSGFLKFIVLTEPGII
CCEEEEEEEECCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCHH
HQAKKILPHGIFFPVESVNSSGTCAMCNKCPHMRLNTMEKLYHCLDKEEPSIEIDPSIFD
HHHHHHCCCCCEEEHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHH
AARSAVENMFFYLNK
HHHHHHHHHHHEECC
>Mature Secondary Structure 
GFLKNLEREIVELKKKKNAVILAHYYQDDELQDIADFVGDSLDLSKKASNTDAEIIVFC
CHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEE
GVTFMGEVAKLLSPGKKVIVPDMAAGCSLEDSCKVEHLKKFISPVENPFVLTYINSSVHV
CHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEE
KAISDSICTSSSAEKIINSIPKEKNIVFAPDKFLGSYLQKRTGRKMKIWQGTCIVHESFS
EEECCHHHCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCCEEEEEECEEEEECCCC
EKHAISLKLENPDAKVVAHPECPDVLIKYADFVGSTSQILSYIKKSGFLKFIVLTEPGII
CCEEEEEEEECCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCHH
HQAKKILPHGIFFPVESVNSSGTCAMCNKCPHMRLNTMEKLYHCLDKEEPSIEIDPSIFD
HHHHHHCCCCCEEEHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHH
AARSAVENMFFYLNK
HHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9297820 [H]