Click here to switch to the map view.

The map label for this gene is ftsA-1 [H]

Identifier: 88607641

GI number: 88607641

Start: 1228892

End: 1230076

Strand: Reverse

Name: ftsA-1 [H]

Synonym: APH_1164

Alternate gene names: 88607641

Gene position: 1230076-1228892 (Counterclockwise)

Preceding gene: 88607079

Following gene: 88607389

Centisome position: 83.61

GC content: 43.88

Gene sequence:

>1185_bases
ATGGGAAGCACGAAGGTAGTGTGTCTTGCGGTCAAAGTAAACGACGAAGGTGTACCAGAAGTTATAGGAGTGGGCTACAA
GCCTTCGGAAGGCATTAACGGCGGTGCAATAGTTAATAAACAAAGCGCAGGATGCTCGGTGCTGTCTAGTATTGATCTTG
CGGAACAAGTTTCAGCACAAACTATAAGTCAAGTATACGTCACTGTATCAGGCTGCGGGGTAAAATCATCCAACATCTCT
AACGAAGTATTGTCAAATGTTCATGAGATCTCTGAGCGTGACATTAGAAGGATCATGTTACAAACCTACGAAAAGTTTTC
TGGTGAAGACATAGCAATTCACAATGTTCCGATGGCATATCATTTGGACAATTTAAGTAACATCACAGAACTGGAAGGTC
TGTATGGCAGTAAACTGCGTGCAGATGTACATGCTGTCACGGTATCAAAGTTGGCGTTGGTGAACATTGAGCAATGCATA
ACTAGCAACAATTTAATGATGGGTGGGTGCGTAGCGGAGTCGTATGCGTCGGGATTAGCTTGCATGACTGACGATGAGCG
GGAGTTGGGTACTTTGGTCATCGACATGGGAAGCAATTACACTTCCATGGGGTTTTTCTATAAGGGGAAGTACGAACACG
CAGATTGCATTCCATTTGGTGGGCATCACATAACGCGTGATGTTTCTTATGGACTATGTGTAAGCTTAAAAGATGCGGAG
AGCATAAAGGTCACGCACGGCAGCACGATGCTTTTCTCATCGGACGACGATTATCCGATTGAGATATGCGATGTAGATGG
AGAGTTGAAATGTGTTACGAGAGCAGACATTGCTAGCATCATTCGTCCAAGAGTTGAGGAGATCTTAGAGTTTGTAAAAA
GCCGGGTAGATGAGCATCGGAATGTAGTAAGTAAGGTTGTCATCACTGGAGGATGCAGCAAATTGCTGGGAATAGAAAAG
GTAGCTAGTTCTATACTTAACCGGCAAGTCAGAGTTGGAACTCCTATTAATCTTAAGGGTATGTGGCCGGAATATGTAGG
CAAGCCTGAAATGTCAGCAGCTGTAGGTTCTGCTATGCTTATAGCACGTACATTTTATAAGAGACAATGTACAAAAAACA
ATTCTCATCATCCGGGCAGCTTGGAGAAGGTCCTACGCTGGATAATTACCAAAGTTGAGGCATAG

Upstream 100 bases:

>100_bases
TTCCACGTCAGAGCTCTTGATAATGTGAGTAGCGAGCGTGTAGTGCTCATTTTTTGAAGACAAGCATGATTCTTACGGGC
TGTGTGCCAGTTTTCTCGAC

Downstream 100 bases:

>100_bases
GCATTAAACCCAAGCATGTCCTGAACCCAGGTTATAAAGATCATTATCTTGTTCTGCAGTTATTTCATACAAGAAGATAC
CCTCGGATTAAAGTCAGGAA

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MGSTKVVCLAVKVNDEGVPEVIGVGYKPSEGINGGAIVNKQSAGCSVLSSIDLAEQVSAQTISQVYVTVSGCGVKSSNIS
NEVLSNVHEISERDIRRIMLQTYEKFSGEDIAIHNVPMAYHLDNLSNITELEGLYGSKLRADVHAVTVSKLALVNIEQCI
TSNNLMMGGCVAESYASGLACMTDDERELGTLVIDMGSNYTSMGFFYKGKYEHADCIPFGGHHITRDVSYGLCVSLKDAE
SIKVTHGSTMLFSSDDDYPIEICDVDGELKCVTRADIASIIRPRVEEILEFVKSRVDEHRNVVSKVVITGGCSKLLGIEK
VASSILNRQVRVGTPINLKGMWPEYVGKPEMSAAVGSAMLIARTFYKRQCTKNNSHHPGSLEKVLRWIITKVEA

Sequences:

>Translated_394_residues
MGSTKVVCLAVKVNDEGVPEVIGVGYKPSEGINGGAIVNKQSAGCSVLSSIDLAEQVSAQTISQVYVTVSGCGVKSSNIS
NEVLSNVHEISERDIRRIMLQTYEKFSGEDIAIHNVPMAYHLDNLSNITELEGLYGSKLRADVHAVTVSKLALVNIEQCI
TSNNLMMGGCVAESYASGLACMTDDERELGTLVIDMGSNYTSMGFFYKGKYEHADCIPFGGHHITRDVSYGLCVSLKDAE
SIKVTHGSTMLFSSDDDYPIEICDVDGELKCVTRADIASIIRPRVEEILEFVKSRVDEHRNVVSKVVITGGCSKLLGIEK
VASSILNRQVRVGTPINLKGMWPEYVGKPEMSAAVGSAMLIARTFYKRQCTKNNSHHPGSLEKVLRWIITKVEA
>Mature_393_residues
GSTKVVCLAVKVNDEGVPEVIGVGYKPSEGINGGAIVNKQSAGCSVLSSIDLAEQVSAQTISQVYVTVSGCGVKSSNISN
EVLSNVHEISERDIRRIMLQTYEKFSGEDIAIHNVPMAYHLDNLSNITELEGLYGSKLRADVHAVTVSKLALVNIEQCIT
SNNLMMGGCVAESYASGLACMTDDERELGTLVIDMGSNYTSMGFFYKGKYEHADCIPFGGHHITRDVSYGLCVSLKDAES
IKVTHGSTMLFSSDDDYPIEICDVDGELKCVTRADIASIIRPRVEEILEFVKSRVDEHRNVVSKVVITGGCSKLLGIEKV
ASSILNRQVRVGTPINLKGMWPEYVGKPEMSAAVGSAMLIARTFYKRQCTKNNSHHPGSLEKVLRWIITKVEA

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=368, Percent_Identity=28.5326086956522, Blast_Score=164, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 42837; Mature: 42705

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSTKVVCLAVKVNDEGVPEVIGVGYKPSEGINGGAIVNKQSAGCSVLSSIDLAEQVSAQ
CCCCEEEEEEEEECCCCCCHHEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
TISQVYVTVSGCGVKSSNISNEVLSNVHEISERDIRRIMLQTYEKFSGEDIAIHNVPMAY
HHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
HLDNLSNITELEGLYGSKLRADVHAVTVSKLALVNIEQCITSNNLMMGGCVAESYASGLA
ECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHCCCE
CMTDDERELGTLVIDMGSNYTSMGFFYKGKYEHADCIPFGGHHITRDVSYGLCVSLKDAE
EECCCCCCCCEEEEECCCCEEEECEEEECCCCCCCCEECCCCEEEECCCCCEEEEECCCC
SIKVTHGSTMLFSSDDDYPIEICDVDGELKCVTRADIASIIRPRVEEILEFVKSRVDEHR
EEEEECCCEEEEECCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVSKVVITGGCSKLLGIEKVASSILNRQVRVGTPINLKGMWPEYVGKPEMSAAVGSAML
HHHHHHEEECCCHHHHHHHHHHHHHHCCCEEECCCEEECCCCHHHCCCCCHHHHHHHHHH
IARTFYKRQCTKNNSHHPGSLEKVLRWIITKVEA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSTKVVCLAVKVNDEGVPEVIGVGYKPSEGINGGAIVNKQSAGCSVLSSIDLAEQVSAQ
CCCEEEEEEEEECCCCCCHHEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
TISQVYVTVSGCGVKSSNISNEVLSNVHEISERDIRRIMLQTYEKFSGEDIAIHNVPMAY
HHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
HLDNLSNITELEGLYGSKLRADVHAVTVSKLALVNIEQCITSNNLMMGGCVAESYASGLA
ECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHCCCE
CMTDDERELGTLVIDMGSNYTSMGFFYKGKYEHADCIPFGGHHITRDVSYGLCVSLKDAE
EECCCCCCCCEEEEECCCCEEEECEEEECCCCCCCCEECCCCEEEECCCCCEEEEECCCC
SIKVTHGSTMLFSSDDDYPIEICDVDGELKCVTRADIASIIRPRVEEILEFVKSRVDEHR
EEEEECCCEEEEECCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVSKVVITGGCSKLLGIEKVASSILNRQVRVGTPINLKGMWPEYVGKPEMSAAVGSAML
HHHHHHEEECCCHHHHHHHHHHHHHHCCCEEECCCEEECCCCHHHCCCCCHHHHHHHHHH
IARTFYKRQCTKNNSHHPGSLEKVLRWIITKVEA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]