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The map label for this gene is coaX

Identifier: 88607377

GI number: 88607377

Start: 1072221

End: 1073012

Strand: Direct

Name: coaX

Synonym: APH_1014

Alternate gene names: 88607377

Gene position: 1072221-1073012 (Clockwise)

Preceding gene: 88607083

Following gene: 88607209

Centisome position: 72.88

GC content: 41.41

Gene sequence:

>792_bases
ATGCTAGCTATAGTTGATGTTGGAAATACCAACATAAAATTCACTTTATATGTCGATGGGGAGTTTTCAGAGAGCTGGTA
TATATCGACTTATCATGAGCGTACAGCCTCTGAACTTTATGCCATACTGCGTGTATTGGCATCTCAGGCCAATATCAATA
TTCACCATTTAGTTGGGGCTGCGGTGTCTAGTGTTTTTCCTGCAGTAAACGGTTCTATAACAGAGATGTTCAAGAGCTTT
TTCAACATTGTACCAGTATTCATAACAAGCGCTCATGCAAGTTTACTGGGAATCAATATATGTTTAGCGCAGAATACGAT
AGGCTCTGATCGCCTTGCTGACATAGTCGCTGCCCGCACATTATACCCTGATAGGGATCTTCTTGTGATAGATATGGGAA
CAATTACCGTTTTTAATCTCGTCAACAAAAATGGAGATCTATACGGACAGGTTCTCTCTCCTGGTCTTGCGTGTCTGGTA
AAGAGCGTGAGGCTGTGCACGGCTGCGCTTCCGCAAGTATGTGTAAATAAACCAACAACTAAGGTAATATCAGATGCTAC
TGCATCATCCTTAGAATCTGGATTGTATTGGGGCTATTTATCAATGGTCGAGGGAGTAATACAGCGAATATTAAAAGAGG
AAAGTGGTAAATCTCTGCAAACAGTCGCTACGGGGGGAGCATCCAACTTCTTTCGCGATACCACTCATGTTCTCTCAATC
GACAAATTATTAACCACAAAAGGCATATTACAGATTTACAGAAAGCTAATAGAGAATGAGGAAGGGCGTTAA

Upstream 100 bases:

>100_bases
TTATTGACAAAATCAACATGGAGCTTGCTGATTTGCTCACACGCGATGGGTTCAATAAAGTGGAGCAAGCCGTAGGAATA
GATGTACATTGACGAGCAAT

Downstream 100 bases:

>100_bases
AGCAGTATGATTGCCTGCTAGTCACTTTAAGCACAAATAACTTACCTCATGCAAAAGCGCTACTGGACAGGAACATAGTG
CTCTGCAACCCGTCTTCTAG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLAIVDVGNTNIKFTLYVDGEFSESWYISTYHERTASELYAILRVLASQANINIHHLVGAAVSSVFPAVNGSITEMFKSF
FNIVPVFITSAHASLLGINICLAQNTIGSDRLADIVAARTLYPDRDLLVIDMGTITVFNLVNKNGDLYGQVLSPGLACLV
KSVRLCTAALPQVCVNKPTTKVISDATASSLESGLYWGYLSMVEGVIQRILKEESGKSLQTVATGGASNFFRDTTHVLSI
DKLLTTKGILQIYRKLIENEEGR

Sequences:

>Translated_263_residues
MLAIVDVGNTNIKFTLYVDGEFSESWYISTYHERTASELYAILRVLASQANINIHHLVGAAVSSVFPAVNGSITEMFKSF
FNIVPVFITSAHASLLGINICLAQNTIGSDRLADIVAARTLYPDRDLLVIDMGTITVFNLVNKNGDLYGQVLSPGLACLV
KSVRLCTAALPQVCVNKPTTKVISDATASSLESGLYWGYLSMVEGVIQRILKEESGKSLQTVATGGASNFFRDTTHVLSI
DKLLTTKGILQIYRKLIENEEGR
>Mature_263_residues
MLAIVDVGNTNIKFTLYVDGEFSESWYISTYHERTASELYAILRVLASQANINIHHLVGAAVSSVFPAVNGSITEMFKSF
FNIVPVFITSAHASLLGINICLAQNTIGSDRLADIVAARTLYPDRDLLVIDMGTITVFNLVNKNGDLYGQVLSPGLACLV
KSVRLCTAALPQVCVNKPTTKVISDATASSLESGLYWGYLSMVEGVIQRILKEESGKSLQTVATGGASNFFRDTTHVLSI
DKLLTTKGILQIYRKLIENEEGR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_ANAPZ (Q2GJ76)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505575.1
- ProteinModelPortal:   Q2GJ76
- SMR:   Q2GJ76
- STRING:   Q2GJ76
- GeneID:   3931110
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_1014
- NMPDR:   fig|212042.5.peg.960
- TIGR:   APH_1014
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   GTACTIF
- ProtClustDB:   PRK13318
- BioCyc:   APHA212042:APH_1014-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28626; Mature: 28626

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: ACT_SITE 110-110 BINDING 134-134 BINDING 187-187

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAIVDVGNTNIKFTLYVDGEFSESWYISTYHERTASELYAILRVLASQANINIHHLVGA
CEEEEEECCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AVSSVFPAVNGSITEMFKSFFNIVPVFITSAHASLLGINICLAQNTIGSDRLADIVAART
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHH
LYPDRDLLVIDMGTITVFNLVNKNGDLYGQVLSPGLACLVKSVRLCTAALPQVCVNKPTT
CCCCCCEEEEEECCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KVISDATASSLESGLYWGYLSMVEGVIQRILKEESGKSLQTVATGGASNFFRDTTHVLSI
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHH
DKLLTTKGILQIYRKLIENEEGR
HHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLAIVDVGNTNIKFTLYVDGEFSESWYISTYHERTASELYAILRVLASQANINIHHLVGA
CEEEEEECCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AVSSVFPAVNGSITEMFKSFFNIVPVFITSAHASLLGINICLAQNTIGSDRLADIVAART
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHH
LYPDRDLLVIDMGTITVFNLVNKNGDLYGQVLSPGLACLVKSVRLCTAALPQVCVNKPTT
CCCCCCEEEEEECCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KVISDATASSLESGLYWGYLSMVEGVIQRILKEESGKSLQTVATGGASNFFRDTTHVLSI
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHH
DKLLTTKGILQIYRKLIENEEGR
HHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA