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The map label for this gene is murB [H]

Identifier: 88607276

GI number: 88607276

Start: 790410

End: 791318

Strand: Reverse

Name: murB [H]

Synonym: APH_0745

Alternate gene names: 88607276

Gene position: 791318-790410 (Counterclockwise)

Preceding gene: 88607872

Following gene: 88607407

Centisome position: 53.78

GC content: 43.12

Gene sequence:

>909_bases
ATGAGTTACACCTTCACAGGTTATAAACTTCCTAAAGTTAGGGGAGTTTATAAAAGAAGCGTAAAAATGCATAGCATGAC
TTGGGTAGGCGTAGGTGGTGTTGCGCCATTGCTATTCAAGCCAAAGGACATAGATGATTTAGCGACCTTTCTAAAGAACA
CTTCATTAACAGCCAGTGCGATAGGTGCTGGCTCTAACGTTATTGTCAGAGATGGTGTATTCAACAATGTTGTGGTAAGG
CTAGAGCGTGAATTTTCAGATATGAGATGCGAAGACAACGCTATTACTGTAGGGTGCGGGGCATCTATATCTGAGCTAGC
TGCGTTTGCTAGGGAAAACTCTCTTTCTGGTTTTGAGTTTTGTGTAGGTATGCCTGGAACTGTAGGGGGCGCGATAGCCA
CTAATGCGCGTTGCCATGGGAAGGATATAGCGTCTATATTACATTCGGTTATTGCAGTAAATGAGTACGGAGAGATTTGT
ACACTGTATAAAGATGACATGCAGTATTCGCGTCGTAGTCATGGTCTAGAAGGCAGATGGGTTTTTGTAGAAGCGAGGTT
TGTGGGTAATCCAGCTGAGTTGAATACTATAAGAAATACAATGAGTGAATTGCTCATAAAACGCAATGCAACTCAGCCAA
TTTACTATGGAAAGTCCATTGGATATATCTTTCAAGATGCAGGTAATGCAGAAGCTAAAGCGCTTATAGAAGAAGCGGGG
TGTCGAGGGTTGCAAGTTGGGTGTGCTGTCGTGTCGGAGAAGCACTGTAACTTTATAGAGAATATCGGAGGAGCTAGTGC
GGCCGAAATAGAGGATTTAGGCAGCGAAGTAAAGCGTCTTGTAAAAGAAAAGACAGGAGTCAATCTAGAATGGAGCATTG
AGTTTTTGGGTGCGCGAGTAGTGAAGTAA

Upstream 100 bases:

>100_bases
ATGTTAGCCGATGATGCCAGAAACATGGTATTTACAGAACGGGTTTTTGCAGAGCAAAATGCAGAAAGTGCAGGATATGA
AATGGGGACATTGTTGAAAA

Downstream 100 bases:

>100_bases
AAATTCCTCTGTGTGCAAGAGAATAGAGATAATACCGATGCTCGCCCGTACTGAGGGTTTTTATAAAGAATCATCTGATA
AATACATGGTGATGTACCTT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSYTFTGYKLPKVRGVYKRSVKMHSMTWVGVGGVAPLLFKPKDIDDLATFLKNTSLTASAIGAGSNVIVRDGVFNNVVVR
LEREFSDMRCEDNAITVGCGASISELAAFARENSLSGFEFCVGMPGTVGGAIATNARCHGKDIASILHSVIAVNEYGEIC
TLYKDDMQYSRRSHGLEGRWVFVEARFVGNPAELNTIRNTMSELLIKRNATQPIYYGKSIGYIFQDAGNAEAKALIEEAG
CRGLQVGCAVVSEKHCNFIENIGGASAAEIEDLGSEVKRLVKEKTGVNLEWSIEFLGARVVK

Sequences:

>Translated_302_residues
MSYTFTGYKLPKVRGVYKRSVKMHSMTWVGVGGVAPLLFKPKDIDDLATFLKNTSLTASAIGAGSNVIVRDGVFNNVVVR
LEREFSDMRCEDNAITVGCGASISELAAFARENSLSGFEFCVGMPGTVGGAIATNARCHGKDIASILHSVIAVNEYGEIC
TLYKDDMQYSRRSHGLEGRWVFVEARFVGNPAELNTIRNTMSELLIKRNATQPIYYGKSIGYIFQDAGNAEAKALIEEAG
CRGLQVGCAVVSEKHCNFIENIGGASAAEIEDLGSEVKRLVKEKTGVNLEWSIEFLGARVVK
>Mature_301_residues
SYTFTGYKLPKVRGVYKRSVKMHSMTWVGVGGVAPLLFKPKDIDDLATFLKNTSLTASAIGAGSNVIVRDGVFNNVVVRL
EREFSDMRCEDNAITVGCGASISELAAFARENSLSGFEFCVGMPGTVGGAIATNARCHGKDIASILHSVIAVNEYGEICT
LYKDDMQYSRRSHGLEGRWVFVEARFVGNPAELNTIRNTMSELLIKRNATQPIYYGKSIGYIFQDAGNAEAKALIEEAGC
RGLQVGCAVVSEKHCNFIENIGGASAAEIEDLGSEVKRLVKEKTGVNLEWSIEFLGARVVK

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32797; Mature: 32666

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTFTGYKLPKVRGVYKRSVKMHSMTWVGVGGVAPLLFKPKDIDDLATFLKNTSLTASA
CCEEECCEECCHHHHHHHHHEEEEEEEEEECCCCCCEEECCCCHHHHHHHHHCCCCCHHH
IGAGSNVIVRDGVFNNVVVRLEREFSDMRCEDNAITVGCGASISELAAFARENSLSGFEF
CCCCCCEEEECCCCCHHHEEEEHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCE
CVGMPGTVGGAIATNARCHGKDIASILHSVIAVNEYGEICTLYKDDMQYSRRSHGLEGRW
EECCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCEE
VFVEARFVGNPAELNTIRNTMSELLIKRNATQPIYYGKSIGYIFQDAGNAEAKALIEEAG
EEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHC
CRGLQVGCAVVSEKHCNFIENIGGASAAEIEDLGSEVKRLVKEKTGVNLEWSIEFLGARV
CCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEE
VK
CC
>Mature Secondary Structure 
SYTFTGYKLPKVRGVYKRSVKMHSMTWVGVGGVAPLLFKPKDIDDLATFLKNTSLTASA
CEEECCEECCHHHHHHHHHEEEEEEEEEECCCCCCEEECCCCHHHHHHHHHCCCCCHHH
IGAGSNVIVRDGVFNNVVVRLEREFSDMRCEDNAITVGCGASISELAAFARENSLSGFEF
CCCCCCEEEECCCCCHHHEEEEHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCE
CVGMPGTVGGAIATNARCHGKDIASILHSVIAVNEYGEICTLYKDDMQYSRRSHGLEGRW
EECCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCEE
VFVEARFVGNPAELNTIRNTMSELLIKRNATQPIYYGKSIGYIFQDAGNAEAKALIEEAG
EEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHC
CRGLQVGCAVVSEKHCNFIENIGGASAAEIEDLGSEVKRLVKEKTGVNLEWSIEFLGARV
CCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEE
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA