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The map label for this gene is lytA [H]

Identifier: 88195707

GI number: 88195707

Start: 1924647

End: 1926092

Strand: Reverse

Name: lytA [H]

Synonym: SAOUHSC_02019

Alternate gene names: 88195707

Gene position: 1926092-1924647 (Counterclockwise)

Preceding gene: 88195708

Following gene: 88195706

Centisome position: 68.27

GC content: 40.8

Gene sequence:

>1446_bases
ATGCAAGCAAAATTAACTAAAAATGAGTTTATAGAGTGGTTGAAAACTTCTGAGGGAAAACAATTCAATGTGGACTTATG
GTATGGATTTCAATGCTTTGATTATGCCAATGCTGGTTGGAAAGTTTTGTTTGGATTACTTCTAAAAGGTTTAGGTGCAA
AAGATATTCCGTTCGCTAACAACTTCGACGGATTAGCTACTGTATACCAAAATACACCGGACTTCTTAGCACAACCTGGC
GACATGGTGGTATTCGGTAGCAACTACGGTGCTGGATATGGTCACGTTGCATGGGTAATTGAAGCAACTTTAGATTACAT
CATTGTATATGAGCAGAATTGGCTAGGCGGTGGCTGGACTGACGGAATCGAACAACCCGGCTGGGGTTGGGAAAAAGTTA
CAAGACGACAACATGCTTATGATTTCCCTATGTGGTTTATCCGTCCGAATTTTAAAAGTGAGACAGCGCCACGATCAGTT
CAATCTCCTACACAAGCACCTAAAAAAGAAACAGCTAAGCCACAACCTAAAGCAGTAGAACTTAAAATCATCAAAGATGT
GGTTAAAGGTTATGACCTACCTAAGCGTGGTAGTAACCCTAAAGGTATAGTTATACACAACGACGCAGGGAGCAAAGGGG
CGACTGCTGAAGCATATCGTAACGGATTAGTAAATGCACCTTTATCAAGATTAGAAGCGGGCATTGCGCATAGTTACGTA
TCAGGCAACACAGTTTGGCAAGCCTTAGATGAATCACAAGTAGGTTGGCATACCGCTAATCAAATAGGTAATAAATATTA
TTACGGTATTGAAGTATGTCAATCAATGGGCGCAGATAACGCGACATTCTTAAAAAATGAACAGGCAACTTTCCAAGAAT
GCGCTAGATTGTTGAAAAAATGGGGATTACCAGCAAACAGAAATACAATCAGATTGCACAATGAATTTACTTCAACATCA
TGCCCTCATAGAAGTTCGGTTTTACACACTGGTTTTGACCCAGTAACTCGCGGTCTATTGCCAGAAGACAAGCGGTTGCA
ACTTAAAGACTACTTTATCAAGCAGATTAGGGCGTACATGGATGGTAAAATACCGGTTGCCACTGTCTCTAATGAGTCAA
GCGCTTCAAGTAATACAGTTAAACCAGTTGCAAGTGCATGGAAACGTAATAAATATGGTACTTACTACATGGAAGAAAGT
GCTAGATTCACAAACGGCAATCAACCAATCACAGTAAGAAAAGTGGGGCCATTCTTATCTTGTCCAGTGGGTTATCAGTT
CCAACCTGGTGGGTATTGTGATTATACAGAAGTGATGTTACAAGATGGTCATGTTTGGGTAGGATATACATGGGAGGGGC
AACGTTATTACTTGCCTATTAGAACATGGAATGGTTCTGCCCCACCTAATCAGATATTAGGTGACTTATGGGGAGAAATC
AGTTAG

Upstream 100 bases:

>100_bases
GCGAAAGCACCAAAAGAATATGATACATCACAACCTTTCACAGACGCCTCTAACGATGTTGGCTTTGATGTGAATGAGTA
TCATCATGGAGGTGGCGACA

Downstream 100 bases:

>100_bases
AATGACATAGTCATGTCTATTTAAGCAGGTGCGTTACATACCTGCTTTCTATTTACATTTAAAGATAAAATGTGCTATTA
TTTTACTAGAACTTTTTAAC

Product: autolysin

Products: NA

Alternate protein names: N-acetylmuramoyl-L-alanine amidase [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MQAKLTKNEFIEWLKTSEGKQFNVDLWYGFQCFDYANAGWKVLFGLLLKGLGAKDIPFANNFDGLATVYQNTPDFLAQPG
DMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWTDGIEQPGWGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSV
QSPTQAPKKETAKPQPKAVELKIIKDVVKGYDLPKRGSNPKGIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
SGNTVWQALDESQVGWHTANQIGNKYYYGIEVCQSMGADNATFLKNEQATFQECARLLKKWGLPANRNTIRLHNEFTSTS
CPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYMDGKIPVATVSNESSASSNTVKPVASAWKRNKYGTYYMEES
ARFTNGNQPITVRKVGPFLSCPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
S

Sequences:

>Translated_481_residues
MQAKLTKNEFIEWLKTSEGKQFNVDLWYGFQCFDYANAGWKVLFGLLLKGLGAKDIPFANNFDGLATVYQNTPDFLAQPG
DMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWTDGIEQPGWGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSV
QSPTQAPKKETAKPQPKAVELKIIKDVVKGYDLPKRGSNPKGIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
SGNTVWQALDESQVGWHTANQIGNKYYYGIEVCQSMGADNATFLKNEQATFQECARLLKKWGLPANRNTIRLHNEFTSTS
CPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYMDGKIPVATVSNESSASSNTVKPVASAWKRNKYGTYYMEES
ARFTNGNQPITVRKVGPFLSCPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
S
>Mature_481_residues
MQAKLTKNEFIEWLKTSEGKQFNVDLWYGFQCFDYANAGWKVLFGLLLKGLGAKDIPFANNFDGLATVYQNTPDFLAQPG
DMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWTDGIEQPGWGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSV
QSPTQAPKKETAKPQPKAVELKIIKDVVKGYDLPKRGSNPKGIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
SGNTVWQALDESQVGWHTANQIGNKYYYGIEVCQSMGADNATFLKNEQATFQECARLLKKWGLPANRNTIRLHNEFTSTS
CPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYMDGKIPVATVSNESSASSNTVKPVASAWKRNKYGTYYMEES
ARFTNGNQPITVRKVGPFLSCPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
S

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase C51 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR007921
- InterPro:   IPR003646
- InterPro:   IPR013667 [H]

Pfam domain/function: PF01510 Amidase_2; PF05257 CHAP; PF08460 SH3_5 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 54030; Mature: 54030

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50911 CHAP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAKLTKNEFIEWLKTSEGKQFNVDLWYGFQCFDYANAGWKVLFGLLLKGLGAKDIPFAN
CCCCCCHHHHHHHHHCCCCCEEEEEEEECEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
NFDGLATVYQNTPDFLAQPGDMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWT
CCCCHHHHHCCCHHHHCCCCCEEEECCCCCCCCCHHHHEEEEEEEEEEEEECCCCCCCCC
DGIEQPGWGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSVQSPTQAPKKETAKPQPKAVE
CCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEH
LKIIKDVVKGYDLPKRGSNPKGIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
HHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHC
SGNTVWQALDESQVGWHTANQIGNKYYYGIEVCQSMGADNATFLKNEQATFQECARLLKK
CCCHHHHHHCCCCCCCCHHHHHCCEEEEHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
WGLPANRNTIRLHNEFTSTSCPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYM
CCCCCCCCEEEEECCCCCCCCCCCCCCEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHH
DGKIPVATVSNESSASSNTVKPVASAWKRNKYGTYYMEESARFTNGNQPITVRKVGPFLS
CCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCEE
CPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
CCCCCEECCCCCCCHHHHEEECCCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHCCC
S
C
>Mature Secondary Structure
MQAKLTKNEFIEWLKTSEGKQFNVDLWYGFQCFDYANAGWKVLFGLLLKGLGAKDIPFAN
CCCCCCHHHHHHHHHCCCCCEEEEEEEECEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
NFDGLATVYQNTPDFLAQPGDMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWT
CCCCHHHHHCCCHHHHCCCCCEEEECCCCCCCCCHHHHEEEEEEEEEEEEECCCCCCCCC
DGIEQPGWGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSVQSPTQAPKKETAKPQPKAVE
CCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEH
LKIIKDVVKGYDLPKRGSNPKGIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
HHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHC
SGNTVWQALDESQVGWHTANQIGNKYYYGIEVCQSMGADNATFLKNEQATFQECARLLKK
CCCHHHHHHCCCCCCCCHHHHHCCEEEEHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
WGLPANRNTIRLHNEFTSTSCPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYM
CCCCCCCCEEEEECCCCCCCCCCCCCCEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHH
DGKIPVATVSNESSASSNTVKPVASAWKRNKYGTYYMEESARFTNGNQPITVRKVGPFLS
CCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCEE
CPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
CCCCCEECCCCCCCHHHHEEECCCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1677905 [H]