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The map label for this gene is era

Identifier: 161353525

GI number: 161353525

Start: 1581790

End: 1582689

Strand: Reverse

Name: era

Synonym: SAOUHSC_01668

Alternate gene names: 161353525

Gene position: 1582689-1581790 (Counterclockwise)

Preceding gene: 88195377

Following gene: 88195374

Centisome position: 56.1

GC content: 33.33

Gene sequence:

>900_bases
ATGACAGAACATAAATCAGGATTTGTTTCAATTATAGGTAGACCAAATGTAGGAAAGTCAACATTTGTTAATAGAGTGAT
CGGCCATAAAATAGCAATCATGTCCGATAAAGCTCAAACAACTAGAAATAAAATTCAAGGTGTTATGACAAGAGATGACG
CGCAAATTATATTCATTGATACGCCAGGTATTCATAAACCTAAACACAAATTAGGTGACTATATGATGAAAGTCGCTAAA
AATACATTATCTGAGATAGATGCAATCATGTTTATGGTTAATGCCAATGAGGAAATTGGACGAGGCGATGAATATATTAT
AGAAATGTTGAAAAATGTTAAGACACCAGTATTTTTAGTATTAAATAAAATAGATTTAGTGCATCCAGATGAATTAATGC
CAAAGATTGAAGAATATCAAAGTTATATGGACTTTACAGAGATTGTACCTATTTCAGCATTAGAAGGGCTAAATGTCGAT
CATTTTATTGATGTTTTAAAGACGTATTTACCCGAAGGACCTAAATATTATCCAGATGATCAAATTTCAGACCATCCTGA
ACAATTTGTAGTGGGTGAAATCATTCGTGAAAAAATCCTTCATCTTACAAGTGAAGAAATCCCTCATGCGATTGGTGTTA
ATGTGGACCGTATGGTTAAAGAAAGCGAAGATCGTGTTCATATCGAAGCAACTATATATGTTGAAAGAGGTTCGCAAAAA
GGAATTGTCATTGGAAAAGGCGGTAAAAAGTTAAAAGAAGTAGGAAAACGTGCGAGACGTGATATAGAAATGCTTCTAGG
CTCTAAAGTTTACTTAGAATTATGGGTCAAAGTTCAAAGAGACTGGCGAAACAAAGTTAACTTTATTCGCCAAATTGGTT
ATGTTGAAGACCAAGATTAA

Upstream 100 bases:

>100_bases
TGATATGCCTGTGTATATGACAAATCATAAAGGAGATATGGTTATGATGACAGTCGCAGAGTTACTACCATTTGGATTTT
CAGGAAAGGATTTAGAATAA

Downstream 100 bases:

>100_bases
TCTTAAAAGTGGTGAAGATAATTGTTAATGCGCCAAAAAGGGATTATCATCAAAGCAGTTGATTATGGTGAATCTGATAA
AATTATCACGATTTTAAATG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAK
NTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVD
HFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERGSQK
GIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD

Sequences:

>Translated_299_residues
MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAK
NTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVD
HFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERGSQK
GIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
>Mature_298_residues
TEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAKN
TLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDH
FIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERGSQKG
IVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=24.0625, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788919, Length=294, Percent_Identity=39.7959183673469, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87082120, Length=182, Percent_Identity=30.2197802197802, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646434, Length=313, Percent_Identity=25.2396166134185, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34271; Mature: 34140

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFID
CCCCCCCCEEEEECCCCCHHHHHHHHHHCEEEEECCHHHHHHHHHHHHEEECCCEEEEEE
TPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEE
LNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDHFIDVLKTYLPEGPKYYPDD
EHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
QISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERGSQK
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHCCCCCEEEEEEEEEEECCCC
GIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
CEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFID
CCCCCCCEEEEECCCCCHHHHHHHHHHCEEEEECCHHHHHHHHHHHHEEECCCEEEEEE
TPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEE
LNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDHFIDVLKTYLPEGPKYYPDD
EHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
QISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERGSQK
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHCCCCCEEEEEEEEEEECCCC
GIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
CEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA