| Definition | Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome. |
|---|---|
| Accession | NC_007794 |
| Length | 3,561,584 |
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The map label for this gene is phbB [H]
Identifier: 87201224
GI number: 87201224
Start: 3428543
End: 3429265
Strand: Reverse
Name: phbB [H]
Synonym: Saro_3212
Alternate gene names: 87201224
Gene position: 3429265-3428543 (Counterclockwise)
Preceding gene: 87201225
Following gene: 87201223
Centisome position: 96.28
GC content: 63.21
Gene sequence:
>723_bases ATGTCGCGAGTTGCAGTCGTTACTGGTGGTACGCGCGGAATTGGCCAGGCAATCTGCCTTGCCCTGCAGGCGCAAGGGCG GACCGTCGTCGCGAACTATGCCGGGAACGAGGAAAAGGCGCGAACCTTTACGGCGGAGACGGGCATTCCGGCCTATCGCT GGGACGTGGGCGATCACGAAGCGACGCTGGAAGGTTGCGCTCGCGTTGCCGCCGAGGTCGGTCCGATCGACATCGTCGTC AACAACGCCGGTATCACGCGGGACGGCGTGCTTCACAAGATGAGCTTCGATGACTGGAACGAGGTGATGCGCATCAACCT CGGCGGATGCTTCAACATGGCAAAGGCGACCTTCTCCGGCATGCGCGAGCGCGGATGGGGCCGTATTGTCAACATCGGCT CGATCAACGGCCAGGCCGGTCAATACGGCCAGGTCAACTATGCCGCCGCCAAGTCGGGCATCCACGGCTTCACCAAGGCA TTGGCGCAGGAAGGTGCGAAGTACGGTGTCACCGTCAACGCGATCGCGCCGGGCTACATCGATACCGACATGGTTGCCGC CGTGCCGCCGCAGGTCCTCGAAAAGATCGTCGCCAAGATCCCCGTCGGCCGGCTAGGGCATGCGGACGAGATCGCGCGGG GAGTTGCCTTCCTCACGGCCGACCAGGGCGGTTTCGTGACCGGATCGACCATGTCGCTCAACGGCGGCCAGCATATGTAC TGA
Upstream 100 bases:
>100_bases ATTCCTCGCGCTTGCGCAGCAATTACGTATTCCCGCGCTTGTCGTATCCCCGTCATGAACCTAGCCTAGTCGCGAGAGGG ATCGATTGGGAGGTACGGTT
Downstream 100 bases:
>100_bases TGGAGATGCCGCGGGCGCTGCGTGCGCTTGCGGCTCCGTCATGCCGGTCCCGTACCACCCTCCGGTCAAACGCTCGGTCG AGATCGCCGGGCACAAGACC
Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 240; Mature: 239
Protein sequence:
>240_residues MSRVAVVTGGTRGIGQAICLALQAQGRTVVANYAGNEEKARTFTAETGIPAYRWDVGDHEATLEGCARVAAEVGPIDIVV NNAGITRDGVLHKMSFDDWNEVMRINLGGCFNMAKATFSGMRERGWGRIVNIGSINGQAGQYGQVNYAAAKSGIHGFTKA LAQEGAKYGVTVNAIAPGYIDTDMVAAVPPQVLEKIVAKIPVGRLGHADEIARGVAFLTADQGGFVTGSTMSLNGGQHMY
Sequences:
>Translated_240_residues MSRVAVVTGGTRGIGQAICLALQAQGRTVVANYAGNEEKARTFTAETGIPAYRWDVGDHEATLEGCARVAAEVGPIDIVV NNAGITRDGVLHKMSFDDWNEVMRINLGGCFNMAKATFSGMRERGWGRIVNIGSINGQAGQYGQVNYAAAKSGIHGFTKA LAQEGAKYGVTVNAIAPGYIDTDMVAAVPPQVLEKIVAKIPVGRLGHADEIARGVAFLTADQGGFVTGSTMSLNGGQHMY >Mature_239_residues SRVAVVTGGTRGIGQAICLALQAQGRTVVANYAGNEEKARTFTAETGIPAYRWDVGDHEATLEGCARVAAEVGPIDIVVN NAGITRDGVLHKMSFDDWNEVMRINLGGCFNMAKATFSGMRERGWGRIVNIGSINGQAGQYGQVNYAAAKSGIHGFTKAL AQEGAKYGVTVNAIAPGYIDTDMVAAVPPQVLEKIVAKIPVGRLGHADEIARGVAFLTADQGGFVTGSTMSLNGGQHMY
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=37.4501992031873, Blast_Score=154, Evalue=6e-38, Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=34.4398340248963, Blast_Score=131, Evalue=5e-31, Organism=Homo sapiens, GI4504505, Length=213, Percent_Identity=33.8028169014084, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=31.3492063492063, Blast_Score=100, Evalue=8e-22, Organism=Homo sapiens, GI7705925, Length=237, Percent_Identity=29.1139240506329, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI10190704, Length=243, Percent_Identity=31.2757201646091, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=32.4607329842932, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=29.8039215686275, Blast_Score=88, Evalue=9e-18, Organism=Homo sapiens, GI66933014, Length=241, Percent_Identity=27.3858921161826, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=28.9795918367347, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI4503817, Length=186, Percent_Identity=31.7204301075269, Blast_Score=85, Evalue=4e-17, Organism=Homo sapiens, GI59889578, Length=174, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI109715829, Length=230, Percent_Identity=27.8260869565217, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=30.4123711340206, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI4503301, Length=206, Percent_Identity=28.1553398058252, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=29.3532338308458, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI4504503, Length=186, Percent_Identity=30.1075268817204, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=28.4210526315789, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=28.125, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI157739938, Length=192, Percent_Identity=26.0416666666667, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI223718074, Length=209, Percent_Identity=27.7511961722488, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI25282469, Length=153, Percent_Identity=30.0653594771242, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=43.0962343096234, Blast_Score=197, Evalue=4e-52, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=34.297520661157, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=32.2448979591837, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=30.5785123966942, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=33.4745762711864, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=29.3388429752066, Blast_Score=110, Evalue=6e-26, Organism=Escherichia coli, GI1790717, Length=237, Percent_Identity=28.6919831223629, Blast_Score=107, Evalue=9e-25, Organism=Escherichia coli, GI1786812, Length=243, Percent_Identity=29.2181069958848, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.4615384615385, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=33.8888888888889, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=27.8008298755187, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=25.7028112449799, Blast_Score=64, Evalue=6e-12, Organism=Escherichia coli, GI1787526, Length=214, Percent_Identity=29.9065420560748, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=42.3868312757202, Blast_Score=172, Evalue=2e-43, Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=40.495867768595, Blast_Score=171, Evalue=4e-43, Organism=Caenorhabditis elegans, GI17568967, Length=185, Percent_Identity=35.1351351351351, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=29.8449612403101, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI115534694, Length=238, Percent_Identity=29.8319327731092, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=29.7619047619048, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=29.2, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=31.2252964426877, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=29.7619047619048, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17538182, Length=249, Percent_Identity=30.1204819277108, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=27.6923076923077, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=29.3650793650794, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17561272, Length=200, Percent_Identity=31, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=28.2352941176471, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=31.2169312169312, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=31.2169312169312, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=26.7175572519084, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=27.4809160305344, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=28.6259541984733, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=28.7878787878788, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17564282, Length=215, Percent_Identity=29.7674418604651, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=26.5151515151515, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=25, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=26.3565891472868, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=28.8973384030418, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.6, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=25.7692307692308, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=24.6268656716418, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=25.1908396946565, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI32563809, Length=197, Percent_Identity=27.4111675126904, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17507613, Length=197, Percent_Identity=27.4111675126904, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=9e-11, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=25.5208333333333, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6322861, Length=205, Percent_Identity=33.1707317073171, Blast_Score=117, Evalue=2e-27, Organism=Saccharomyces cerevisiae, GI6324126, Length=184, Percent_Identity=29.8913043478261, Blast_Score=75, Evalue=1e-14, Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=39.8340248962656, Blast_Score=158, Evalue=2e-39, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=31.2, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI18859837, Length=216, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=8e-24, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=30.1204819277108, Blast_Score=101, Evalue=3e-22, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.6, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.8, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24643142, Length=238, Percent_Identity=28.1512605042017, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.0196078431373, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24641232, Length=234, Percent_Identity=31.1965811965812, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI24581726, Length=216, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=30.5389221556886, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24644337, Length=172, Percent_Identity=30.8139534883721, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=32.3232323232323, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=32.258064516129, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=32.258064516129, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=27.3684210526316, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24641388, Length=207, Percent_Identity=29.951690821256, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI21356301, Length=186, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=29.7979797979798, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24665243, Length=189, Percent_Identity=31.2169312169312, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI221331216, Length=199, Percent_Identity=29.1457286432161, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI24665247, Length=190, Percent_Identity=30.5263157894737, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI116007234, Length=202, Percent_Identity=28.2178217821782, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 25217; Mature: 25086
Theoretical pI: Translated: 7.55; Mature: 7.55
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSRVAVVTGGTRGIGQAICLALQAQGRTVVANYAGNEEKARTFTAETGIPAYRWDVGDHE CCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHEEEEECCCCCEEEECCCCCH ATLEGCARVAAEVGPIDIVVNNAGITRDGVLHKMSFDDWNEVMRINLGGCFNMAKATFSG HHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHH MRERGWGRIVNIGSINGQAGQYGQVNYAAAKSGIHGFTKALAQEGAKYGVTVNAIAPGYI HHHCCCCEEEEEECCCCCCCCCCCEEHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCC DTDMVAAVPPQVLEKIVAKIPVGRLGHADEIARGVAFLTADQGGFVTGSTMSLNGGQHMY CCCHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCEEEEEECCCCEEECCEEEECCCCCCC >Mature Secondary Structure SRVAVVTGGTRGIGQAICLALQAQGRTVVANYAGNEEKARTFTAETGIPAYRWDVGDHE CEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHEEEEECCCCCEEEECCCCCH ATLEGCARVAAEVGPIDIVVNNAGITRDGVLHKMSFDDWNEVMRINLGGCFNMAKATFSG HHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHH MRERGWGRIVNIGSINGQAGQYGQVNYAAAKSGIHGFTKALAQEGAKYGVTVNAIAPGYI HHHCCCCEEEEEECCCCCCCCCCCEEHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCC DTDMVAAVPPQVLEKIVAKIPVGRLGHADEIARGVAFLTADQGGFVTGSTMSLNGGQHMY CCCHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCEEEEEECCCCEEECCEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7582015; 11481430 [H]