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The map label for this gene is ytfL [C]

Identifier: 87201186

GI number: 87201186

Start: 3389088

End: 3390464

Strand: Direct

Name: ytfL [C]

Synonym: Saro_3174

Alternate gene names: 87201186

Gene position: 3389088-3390464 (Clockwise)

Preceding gene: 87201183

Following gene: 87201191

Centisome position: 95.16

GC content: 66.16

Gene sequence:

>1377_bases
ATGCGGGTGCTCTTCGCCTTTTCGCTTAAATCTGTTAGGGGCCTGTGCGTGACACCTTTTCCATGGTCTGACGTCTTCGT
GATCCTGGGCCTCGTCCTGCTCAATGGCCTGTTTTCCATGTCGGAACTGGCGATCGTTTCGGCACGCCCGGCGCGCCTGA
AGGTTGCCGCGGAGGAAGGCAGCAAGGGCGCGAAGGTTGCGCTGGCGCTCGCAGCCGACCCCGGAAAATTTCTTTCGACC
GTACAGATCGGGATCACCCTCGTCGGCATCATCGCAGGCGCCTATTCAGGGTCCAGCCTCGGCGGGCCGATGGCGGAGCG
GCTCGCCGCATGGGGTTTTCCGGCCCGTTACGCGGACGATGCCGGGTTCGTCATCGTCATCGCCTTCACCACGTACCTGA
GCCTCGTCGTCGGCGAACTCGTACCCAAGCAGCTCGCGCTGCGTGCGGCGGAACCGATCGCCAAGATCGCGGCGCCCGCC
ATGGCGCTCATGTCGAAGGTGACGGCCCCCTTCGTCTGGCTGCTCGACAACTCGTCCAGCCTGCTCATCCGCCTGCTCGG
CCTCAAGCAGGGCACGGACCAGGAAGTGACCGCCGAAGAACTCCACATGATCTTCGCCGAGGCGACCCGCTCCGGCGTGA
TCGAGGAGGAGGAGCGGGCGCTGATGACGGGCATCATGCGCCTTGCGGAACGCCCGGTGCGCGAAGTGATGACGCCGCGA
ACCGAACTGCACTGGATCGAGCGCAAGGCCCCCGAGGCCGAACTGCGCAGCGCGATCGAGGACAGCCCGCACTCGCTGCT
GCTGGTGGCCGACGGGTCGGTCGACAAGATCGTCGGCGTGGTCAAGGTGCGCGACGTGCTGTCCACGCTGTTGCGGGGAC
GCAAGGTCCAGCTCGGACGCCTGATGAAGAAGCCGGCCATCGTTCCGGACCAGCTCGACACGATGGACGCGCTCGGCATG
ATCCAGCAGGCCGAGGTCGCGATTGCGCTGGTCCACGACGAGTACGGCCATCTCGAAGGCATCGTCACCCCGGCCGACCT
GCTGTCCGCCATCGCGGGCAATTTCGTCGGCCACGCGGACGCGGGCGACGAACCCATGGTGGTCGAGCGCGAGGACGGTT
CACTGCTGATTTCGGGCGCCCTGCCCGCCGACGCCCTTTCCGACCGGCTGGGCCTCGACCTGCCCGACGACCGTGAGTTC
GCGACGACGGCGGGCTACTGCCTTTCGGTGCTCAAGCGACTGCCGAACGAGGGCGAGCATTTTCACGACCAGGGCTGGCG
CTTCGAAGTGGTCGACATGGACGGGCGCAAGATCGACAAGCTGCTGGTCTGCCGCAGCAAGGCAATGCCCATCGCCGCGC
CGGAAGCCGACGGCTGA

Upstream 100 bases:

>100_bases
ACCTTATGCAACGCGATGCCGCTTTGACAGACTGAAATACGCCGGGTTTGGCTGAACGGTTCCCGAACGCCCTTCCACAG
TTGCTGTCTTATCGGGAACA

Downstream 100 bases:

>100_bases
GACCGTCAGCCGGACGGCCTTTCCCACCCGGTACGAGCCAACGAGAAAGGGCGCCGTCGCGGGCGCCCTTTTCGTTGTTC
GGTCGATTTCGCGACGGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MRVLFAFSLKSVRGLCVTPFPWSDVFVILGLVLLNGLFSMSELAIVSARPARLKVAAEEGSKGAKVALALAADPGKFLST
VQIGITLVGIIAGAYSGSSLGGPMAERLAAWGFPARYADDAGFVIVIAFTTYLSLVVGELVPKQLALRAAEPIAKIAAPA
MALMSKVTAPFVWLLDNSSSLLIRLLGLKQGTDQEVTAEELHMIFAEATRSGVIEEEERALMTGIMRLAERPVREVMTPR
TELHWIERKAPEAELRSAIEDSPHSLLLVADGSVDKIVGVVKVRDVLSTLLRGRKVQLGRLMKKPAIVPDQLDTMDALGM
IQQAEVAIALVHDEYGHLEGIVTPADLLSAIAGNFVGHADAGDEPMVVEREDGSLLISGALPADALSDRLGLDLPDDREF
ATTAGYCLSVLKRLPNEGEHFHDQGWRFEVVDMDGRKIDKLLVCRSKAMPIAAPEADG

Sequences:

>Translated_458_residues
MRVLFAFSLKSVRGLCVTPFPWSDVFVILGLVLLNGLFSMSELAIVSARPARLKVAAEEGSKGAKVALALAADPGKFLST
VQIGITLVGIIAGAYSGSSLGGPMAERLAAWGFPARYADDAGFVIVIAFTTYLSLVVGELVPKQLALRAAEPIAKIAAPA
MALMSKVTAPFVWLLDNSSSLLIRLLGLKQGTDQEVTAEELHMIFAEATRSGVIEEEERALMTGIMRLAERPVREVMTPR
TELHWIERKAPEAELRSAIEDSPHSLLLVADGSVDKIVGVVKVRDVLSTLLRGRKVQLGRLMKKPAIVPDQLDTMDALGM
IQQAEVAIALVHDEYGHLEGIVTPADLLSAIAGNFVGHADAGDEPMVVEREDGSLLISGALPADALSDRLGLDLPDDREF
ATTAGYCLSVLKRLPNEGEHFHDQGWRFEVVDMDGRKIDKLLVCRSKAMPIAAPEADG
>Mature_458_residues
MRVLFAFSLKSVRGLCVTPFPWSDVFVILGLVLLNGLFSMSELAIVSARPARLKVAAEEGSKGAKVALALAADPGKFLST
VQIGITLVGIIAGAYSGSSLGGPMAERLAAWGFPARYADDAGFVIVIAFTTYLSLVVGELVPKQLALRAAEPIAKIAAPA
MALMSKVTAPFVWLLDNSSSLLIRLLGLKQGTDQEVTAEELHMIFAEATRSGVIEEEERALMTGIMRLAERPVREVMTPR
TELHWIERKAPEAELRSAIEDSPHSLLLVADGSVDKIVGVVKVRDVLSTLLRGRKVQLGRLMKKPAIVPDQLDTMDALGM
IQQAEVAIALVHDEYGHLEGIVTPADLLSAIAGNFVGHADAGDEPMVVEREDGSLLISGALPADALSDRLGLDLPDDREF
ATTAGYCLSVLKRLPNEGEHFHDQGWRFEVVDMDGRKIDKLLVCRSKAMPIAAPEADG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=402, Percent_Identity=27.363184079602, Blast_Score=166, Evalue=5e-41,
Organism=Escherichia coli, GI1790664, Length=435, Percent_Identity=28.9655172413793, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87082033, Length=273, Percent_Identity=30.03663003663, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI145693175, Length=411, Percent_Identity=26.2773722627737, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1788119, Length=272, Percent_Identity=30.5147058823529, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786879, Length=241, Percent_Identity=23.6514522821577, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49200; Mature: 49200

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLFAFSLKSVRGLCVTPFPWSDVFVILGLVLLNGLFSMSELAIVSARPARLKVAAEEG
CEEEEEEEHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCC
SKGAKVALALAADPGKFLSTVQIGITLVGIIAGAYSGSSLGGPMAERLAAWGFPARYADD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCC
AGFVIVIAFTTYLSLVVGELVPKQLALRAAEPIAKIAAPAMALMSKVTAPFVWLLDNSSS
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCH
LLIRLLGLKQGTDQEVTAEELHMIFAEATRSGVIEEEERALMTGIMRLAERPVREVMTPR
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TELHWIERKAPEAELRSAIEDSPHSLLLVADGSVDKIVGVVKVRDVLSTLLRGRKVQLGR
HHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
LMKKPAIVPDQLDTMDALGMIQQAEVAIALVHDEYGHLEGIVTPADLLSAIAGNFVGHAD
HHHCCCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCC
AGDEPMVVEREDGSLLISGALPADALSDRLGLDLPDDREFATTAGYCLSVLKRLPNEGEH
CCCCCEEEEECCCCEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
FHDQGWRFEVVDMDGRKIDKLLVCRSKAMPIAAPEADG
CCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLFAFSLKSVRGLCVTPFPWSDVFVILGLVLLNGLFSMSELAIVSARPARLKVAAEEG
CEEEEEEEHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCC
SKGAKVALALAADPGKFLSTVQIGITLVGIIAGAYSGSSLGGPMAERLAAWGFPARYADD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCC
AGFVIVIAFTTYLSLVVGELVPKQLALRAAEPIAKIAAPAMALMSKVTAPFVWLLDNSSS
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCH
LLIRLLGLKQGTDQEVTAEELHMIFAEATRSGVIEEEERALMTGIMRLAERPVREVMTPR
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TELHWIERKAPEAELRSAIEDSPHSLLLVADGSVDKIVGVVKVRDVLSTLLRGRKVQLGR
HHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
LMKKPAIVPDQLDTMDALGMIQQAEVAIALVHDEYGHLEGIVTPADLLSAIAGNFVGHAD
HHHCCCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCC
AGDEPMVVEREDGSLLISGALPADALSDRLGLDLPDDREFATTAGYCLSVLKRLPNEGEH
CCCCCEEEEECCCCEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
FHDQGWRFEVVDMDGRKIDKLLVCRSKAMPIAAPEADG
CCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]