Click here to switch to the map view.

The map label for this gene is garP [H]

Identifier: 87201148

GI number: 87201148

Start: 3346614

End: 3348206

Strand: Reverse

Name: garP [H]

Synonym: Saro_3136

Alternate gene names: 87201148

Gene position: 3348206-3346614 (Counterclockwise)

Preceding gene: 87201149

Following gene: 87201128

Centisome position: 94.01

GC content: 65.35

Gene sequence:

>1593_bases
ATGACGGAACCCGGTACGGCGGCGGCTGACAGCACCACGCAGCAGGAGAATGGTGGGGAGGCCACGGCCTATAGCTGGTA
CGTGCTGGGCGTCCTGGTGCTGGTCTATATCCTGAACTTCGTCGACCGGCAGATCCTTTCGATCCTCGCCAACGATATCA
AGAAGGACCTGTCGCTTACCGACGCGGACCTCGGTTTCCTGTATGGGACGGCGTTCGCGGTATTCTATTCGCTGTTCGGC
ATTCCGCTGGGCAGACTGGCAGACAACTGGCACCGGGTGCGGCTTATGAGCATCGGCCTCGCCGTCTGGTCGGCGATGAC
GGCCGTGTCGGGCCTCTCGCGGAGCGGAGTCCAGCTCACGGTTGCGCGCATTGGGGTCGGTGTAGGGGAGGCAACGGCGA
GCCCCGCCGCCTATTCGTTGATATCGGACTACTTTCCCCAACGCCTGCGCGCCACGGCCCTGGCGATCTATTCCTCGGGC
CTGTTCCTGGGCGGCGGGCTTTCGCTGCTGGTCGGGGGGCTCATCGTCGAGCAGTGGAACGCAGCCTATCCGGGGGGCGG
TCCGATGGGGCTGGTCGGTTGGCAGGCGGCCTTCATGGCGGTGGGATTGCCGGGCCTTGCCCTGTCGCTCTGGGTCGCGA
CGATCCGGGAGCCTATCCGCGGCGCGATCGACGGGCTTGCGACGCCCACCACGGAAGCGCCGTTCCGGGGCTTCATTGCA
GAGCTTGCCAATGTCATCCCGCCCTTCACCGTCATAGGCGCGGCGCGGCGGGGCGCTTCGGCGCTTGTGGCAAATCTCGT
GGCGGCAGGAGTGATCTTCGCCGCGATCCAGATCCTGACCGGTGTTCTTGGCGTTACAACCAGGCAGCAATGGATATTCG
TGGGCATTGGTGTCTACGCGGTATTCAGCTGGGCCAGCGCGCTGCGCTCGCGCGATCTGCCCACCTTTCGCGTGATCTGG
GCGTCCCCGGCGTTCATCTGCACTACGCTCGGTTACGGGATGGTGGCCTTCACCTCGTATGCCTCGTCATATTGGGCGGC
GCCCTATGCAGAACGCGTGTTCGGCATAGCCAAGGCGGAGCTGGGCTGGTTCATCGGTGCGCCGGGCGCCCTCGCCGGGT
TCCTCGGCGTGATCCTTGGTGGACGGATTGCGGACTACCTCCATTCCCGCGTTGCGGCGGGTCGGCTCTACGTCACGCTT
TTCGGATTGCTTGCAGCGATCCTGCCGCTGATCGGTGCATTCACCACCAACAGTTTCGCGGCATTTGTCGTCTACTCGTT
CGTCGCTCAGGTGATGTCGAGCAGCGCTTTGGGAGGGGCCGCCGCGACAAGCCAGTCCCTGGTGCTTCCCCGCATGAGGG
GCACGGCGACGGCGACATTCTTTCTGGCAACGACCCTGGTAGGTCTCGCGCTCGGCCCGTTCATGGCGGGGTACGTTTCC
GCGACAAATGCCGACAACCTCTCGGCTGGCGTTCTTTCCACGCTTGTGGCGGCGCCAGTCGGCCTGGTCCTGTTGCTCGT
GGCGATCCGCAGCGTCCCGGCTGCGCAAGCGGGCCTGATCGCCCGCGCCCGCGCCGCCGGAGAGCCGCTCTAG

Upstream 100 bases:

>100_bases
GATAGCTGGTCTTGCTACGATCCCCTGCCGGATGGGAGAGCCTGCGGTGTCTGCGACAGTTGTCGACTGAGGCGCGCGGG
ATTTGAAGAGGCAGGCCTGA

Downstream 100 bases:

>100_bases
GTCTACTGTCGGAGCCTCAGCGCGCCTCGCTGACGAGAACGCCGCAAGCAATGCGTCCGCCGCTGTTGCCCGCCGGATCT
GTCTTGTAATCGTCGGGGCC

Product: major facilitator transporter

Products: NA

Alternate protein names: D-galactarate permease [H]

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MTEPGTAAADSTTQQENGGEATAYSWYVLGVLVLVYILNFVDRQILSILANDIKKDLSLTDADLGFLYGTAFAVFYSLFG
IPLGRLADNWHRVRLMSIGLAVWSAMTAVSGLSRSGVQLTVARIGVGVGEATASPAAYSLISDYFPQRLRATALAIYSSG
LFLGGGLSLLVGGLIVEQWNAAYPGGGPMGLVGWQAAFMAVGLPGLALSLWVATIREPIRGAIDGLATPTTEAPFRGFIA
ELANVIPPFTVIGAARRGASALVANLVAAGVIFAAIQILTGVLGVTTRQQWIFVGIGVYAVFSWASALRSRDLPTFRVIW
ASPAFICTTLGYGMVAFTSYASSYWAAPYAERVFGIAKAELGWFIGAPGALAGFLGVILGGRIADYLHSRVAAGRLYVTL
FGLLAAILPLIGAFTTNSFAAFVVYSFVAQVMSSSALGGAAATSQSLVLPRMRGTATATFFLATTLVGLALGPFMAGYVS
ATNADNLSAGVLSTLVAAPVGLVLLLVAIRSVPAAQAGLIARARAAGEPL

Sequences:

>Translated_530_residues
MTEPGTAAADSTTQQENGGEATAYSWYVLGVLVLVYILNFVDRQILSILANDIKKDLSLTDADLGFLYGTAFAVFYSLFG
IPLGRLADNWHRVRLMSIGLAVWSAMTAVSGLSRSGVQLTVARIGVGVGEATASPAAYSLISDYFPQRLRATALAIYSSG
LFLGGGLSLLVGGLIVEQWNAAYPGGGPMGLVGWQAAFMAVGLPGLALSLWVATIREPIRGAIDGLATPTTEAPFRGFIA
ELANVIPPFTVIGAARRGASALVANLVAAGVIFAAIQILTGVLGVTTRQQWIFVGIGVYAVFSWASALRSRDLPTFRVIW
ASPAFICTTLGYGMVAFTSYASSYWAAPYAERVFGIAKAELGWFIGAPGALAGFLGVILGGRIADYLHSRVAAGRLYVTL
FGLLAAILPLIGAFTTNSFAAFVVYSFVAQVMSSSALGGAAATSQSLVLPRMRGTATATFFLATTLVGLALGPFMAGYVS
ATNADNLSAGVLSTLVAAPVGLVLLLVAIRSVPAAQAGLIARARAAGEPL
>Mature_529_residues
TEPGTAAADSTTQQENGGEATAYSWYVLGVLVLVYILNFVDRQILSILANDIKKDLSLTDADLGFLYGTAFAVFYSLFGI
PLGRLADNWHRVRLMSIGLAVWSAMTAVSGLSRSGVQLTVARIGVGVGEATASPAAYSLISDYFPQRLRATALAIYSSGL
FLGGGLSLLVGGLIVEQWNAAYPGGGPMGLVGWQAAFMAVGLPGLALSLWVATIREPIRGAIDGLATPTTEAPFRGFIAE
LANVIPPFTVIGAARRGASALVANLVAAGVIFAAIQILTGVLGVTTRQQWIFVGIGVYAVFSWASALRSRDLPTFRVIWA
SPAFICTTLGYGMVAFTSYASSYWAAPYAERVFGIAKAELGWFIGAPGALAGFLGVILGGRIADYLHSRVAAGRLYVTLF
GLLAAILPLIGAFTTNSFAAFVVYSFVAQVMSSSALGGAAATSQSLVLPRMRGTATATFFLATTLVGLALGPFMAGYVSA
TNADNLSAGVLSTLVAAPVGLVLLLVAIRSVPAAQAGLIARARAAGEPL

Specific function: Uptake of D-galactarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI1789515, Length=238, Percent_Identity=26.890756302521, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI2367379, Length=163, Percent_Identity=26.9938650306748, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789152, Length=220, Percent_Identity=27.7272727272727, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082320, Length=192, Percent_Identity=28.6458333333333, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71992409, Length=228, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17557872, Length=313, Percent_Identity=24.9201277955272, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24654037, Length=201, Percent_Identity=25.8706467661692, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654039, Length=284, Percent_Identity=23.943661971831, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864456, Length=284, Percent_Identity=23.943661971831, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654041, Length=201, Percent_Identity=25.8706467661692, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654044, Length=201, Percent_Identity=25.8706467661692, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24640209, Length=164, Percent_Identity=28.0487804878049, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 54960; Mature: 54828

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPGTAAADSTTQQENGGEATAYSWYVLGVLVLVYILNFVDRQILSILANDIKKDLSLT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DADLGFLYGTAFAVFYSLFGIPLGRLADNWHRVRLMSIGLAVWSAMTAVSGLSRSGVQLT
CHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
VARIGVGVGEATASPAAYSLISDYFPQRLRATALAIYSSGLFLGGGLSLLVGGLIVEQWN
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
AAYPGGGPMGLVGWQAAFMAVGLPGLALSLWVATIREPIRGAIDGLATPTTEAPFRGFIA
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ELANVIPPFTVIGAARRGASALVANLVAAGVIFAAIQILTGVLGVTTRQQWIFVGIGVYA
HHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH
VFSWASALRSRDLPTFRVIWASPAFICTTLGYGMVAFTSYASSYWAAPYAERVFGIAKAE
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGWFIGAPGALAGFLGVILGGRIADYLHSRVAAGRLYVTLFGLLAAILPLIGAFTTNSFA
HCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AFVVYSFVAQVMSSSALGGAAATSQSLVLPRMRGTATATFFLATTLVGLALGPFMAGYVS
HHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATNADNLSAGVLSTLVAAPVGLVLLLVAIRSVPAAQAGLIARARAAGEPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEPGTAAADSTTQQENGGEATAYSWYVLGVLVLVYILNFVDRQILSILANDIKKDLSLT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DADLGFLYGTAFAVFYSLFGIPLGRLADNWHRVRLMSIGLAVWSAMTAVSGLSRSGVQLT
CHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
VARIGVGVGEATASPAAYSLISDYFPQRLRATALAIYSSGLFLGGGLSLLVGGLIVEQWN
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
AAYPGGGPMGLVGWQAAFMAVGLPGLALSLWVATIREPIRGAIDGLATPTTEAPFRGFIA
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ELANVIPPFTVIGAARRGASALVANLVAAGVIFAAIQILTGVLGVTTRQQWIFVGIGVYA
HHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH
VFSWASALRSRDLPTFRVIWASPAFICTTLGYGMVAFTSYASSYWAAPYAERVFGIAKAE
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGWFIGAPGALAGFLGVILGGRIADYLHSRVAAGRLYVTLFGLLAAILPLIGAFTTNSFA
HCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AFVVYSFVAQVMSSSALGGAAATSQSLVLPRMRGTATATFFLATTLVGLALGPFMAGYVS
HHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATNADNLSAGVLSTLVAAPVGLVLLLVAIRSVPAAQAGLIARARAAGEPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]