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The map label for this gene is queC

Identifier: 87201149

GI number: 87201149

Start: 3348178

End: 3348879

Strand: Reverse

Name: queC

Synonym: Saro_3137

Alternate gene names: 87201149

Gene position: 3348879-3348178 (Counterclockwise)

Preceding gene: 87201150

Following gene: 87201148

Centisome position: 94.03

GC content: 65.67

Gene sequence:

>702_bases
ATGCCGTCGAATTCACCTGCACCAGATGCTCCGCTTGCCGTTGTCCTGCTGTCGGGAGGCCTCGATTCGATGGTCTGCGC
GGGACTGGCCCAGGAGCAGGGCTTCCGGGTCCTGGCGCTGACGATCGACTACAACCAGCGCCACCGTGTGGAACTGGATG
CCGCAAGGGCGATCGCTGCCCGTCTCGGCGTCGAGCGTCACGTGATCCTGCCGCTGGACCTGCGCCAGTTCGGCGGCTCG
GCGCTGACGGCGGACATCGCGGTTCCCAAGGACGGCGTGGGTGACGACATTCCCGTGACCTACGTGCCGGCCCGGAACCT
GATCTTCCTTTCGCTGGCGCTGGCCTGGGCGGAAGCTGCGGGATCCAAGGACCTGTTCATCGGCGTGAACGCGCTGGATT
ATTCGGGTTATCCCGATTGCCGGCCCGAATTCGTGGCGGGCTTCGAAGATCTGGCCCGCATCGCCACCAAGGTGGGCAGC
GAAGGCGGCACGGTGACCGTCCATGCTCCGCTCCAGCACCTCAAGAAATCGGAAATTGCGCGCGAAGCGGCGCGACTGGG
GCTCGAGGCGGGCGATAGCTGGTCTTGCTACGATCCCCTGCCGGATGGGAGAGCCTGCGGTGTCTGCGACAGTTGTCGAC
TGAGGCGCGCGGGATTTGAAGAGGCAGGCCTGAATGACGGAACCCGGTACGGCGGCGGCTGA

Upstream 100 bases:

>100_bases
GCGGCCGAGGCGCGGCGCGTGGCGTCCTGCGGGCGCTGAGAGGCGAAAGGTTCAACCGAAACCATTGCATCGCCGCAACG
GCGCGGCTAGCCCATTGGCG

Downstream 100 bases:

>100_bases
CAGCACCACGCAGCAGGAGAATGGTGGGGAGGCCACGGCCTATAGCTGGTACGTGCTGGGCGTCCTGGTGCTGGTCTATA
TCCTGAACTTCGTCGACCGG

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MPSNSPAPDAPLAVVLLSGGLDSMVCAGLAQEQGFRVLALTIDYNQRHRVELDAARAIAARLGVERHVILPLDLRQFGGS
ALTADIAVPKDGVGDDIPVTYVPARNLIFLSLALAWAEAAGSKDLFIGVNALDYSGYPDCRPEFVAGFEDLARIATKVGS
EGGTVTVHAPLQHLKKSEIAREAARLGLEAGDSWSCYDPLPDGRACGVCDSCRLRRAGFEEAGLNDGTRYGGG

Sequences:

>Translated_233_residues
MPSNSPAPDAPLAVVLLSGGLDSMVCAGLAQEQGFRVLALTIDYNQRHRVELDAARAIAARLGVERHVILPLDLRQFGGS
ALTADIAVPKDGVGDDIPVTYVPARNLIFLSLALAWAEAAGSKDLFIGVNALDYSGYPDCRPEFVAGFEDLARIATKVGS
EGGTVTVHAPLQHLKKSEIAREAARLGLEAGDSWSCYDPLPDGRACGVCDSCRLRRAGFEEAGLNDGTRYGGG
>Mature_232_residues
PSNSPAPDAPLAVVLLSGGLDSMVCAGLAQEQGFRVLALTIDYNQRHRVELDAARAIAARLGVERHVILPLDLRQFGGSA
LTADIAVPKDGVGDDIPVTYVPARNLIFLSLALAWAEAAGSKDLFIGVNALDYSGYPDCRPEFVAGFEDLARIATKVGSE
GGTVTVHAPLQHLKKSEIAREAARLGLEAGDSWSCYDPLPDGRACGVCDSCRLRRAGFEEAGLNDGTRYGGG

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=215, Percent_Identity=37.6744186046512, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_NOVAD (Q2G3K1)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_498406.1
- ProteinModelPortal:   Q2G3K1
- SMR:   Q2G3K1
- STRING:   Q2G3K1
- GeneID:   3918179
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_3137
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q2G3K1
- ProtClustDB:   CLSK844173
- BioCyc:   NARO279238:SARO_3137-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24577; Mature: 24446

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSNSPAPDAPLAVVLLSGGLDSMVCAGLAQEQGFRVLALTIDYNQRHRVELDAARAIAA
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEHHHHHHHHH
RLGVERHVILPLDLRQFGGSALTADIAVPKDGVGDDIPVTYVPARNLIFLSLALAWAEAA
HHCCCCEEEEEECHHHHCCCEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHC
GSKDLFIGVNALDYSGYPDCRPEFVAGFEDLARIATKVGSEGGTVTVHAPLQHLKKSEIA
CCCEEEEEEEEECCCCCCCCCHHHHHCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
REAARLGLEAGDSWSCYDPLPDGRACGVCDSCRLRRAGFEEAGLNDGTRYGGG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSNSPAPDAPLAVVLLSGGLDSMVCAGLAQEQGFRVLALTIDYNQRHRVELDAARAIAA
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEHHHHHHHHH
RLGVERHVILPLDLRQFGGSALTADIAVPKDGVGDDIPVTYVPARNLIFLSLALAWAEAA
HHCCCCEEEEEECHHHHCCCEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHC
GSKDLFIGVNALDYSGYPDCRPEFVAGFEDLARIATKVGSEGGTVTVHAPLQHLKKSEIA
CCCEEEEEEEEECCCCCCCCCHHHHHCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
REAARLGLEAGDSWSCYDPLPDGRACGVCDSCRLRRAGFEEAGLNDGTRYGGG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA