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The map label for this gene is clpX

Identifier: 87201066

GI number: 87201066

Start: 3269818

End: 3271074

Strand: Reverse

Name: clpX

Synonym: Saro_3054

Alternate gene names: 87201066

Gene position: 3271074-3269818 (Counterclockwise)

Preceding gene: 87201067

Following gene: 87201060

Centisome position: 91.84

GC content: 61.58

Gene sequence:

>1257_bases
ATGACCAAGCTTTCCGGATCGGATACCAAGAGCACCCTCTACTGCAGCTTCTGCGGGAAATCGCAGCACGAGGTGCGCAA
GCTGATCGCCGGGCCGACCGTGTTCATCTGCGATGAATGCGTCGAACTGTGCAACGACATCATCCGTGAAGAGACCAAGG
CCGGCATCGCCGGGAAGAAGGACGGTGGCGTACCCACGCCGCGCGACATCTTCGAGACTCTGAACGATTATGTGATCGGC
CAGGACCGCGCCAAGCGCGTGCTCTCGGTTGCAGTCCACAACCACTACAAGCGCCTCAAGCACAGCGGCAAGGGCGGCGA
CGTCGAACTGTCGAAGTCGAACATCCTGCTCGTCGGTCCGACCGGCTCGGGCAAGACCCTGCTTGCGCAGACGCTGGCCA
AGACCTTCGACGTGCCGTTCACGATGGCGGATGCGACGACGCTGACCGAAGCCGGCTACGTGGGCGAGGACGTCGAGAAC
ATCATTCTCAAGCTGCTCCAGGCCTCGGACTACAACGTCGAGAAGGCCCAGCACGGCATCGTCTACATCGACGAGATCGA
CAAGATCAGCCGCAAGGCGGAAAATCCGTCGATCACGCGCGACGTGTCGGGCGAAGGCGTGCAGCAGGCCCTGCTCAAGC
TGATGGAAGGGACGACCGCCTCGGTTCCGCCGCAGGGCGGGCGCAAGCATCCGCAGCAGGAATTCCTCCAGGTCGACACC
ACGAACATCCTGTTCATCTGTGGCGGCGCCTTCGCGGGCCTCGAAAAGATCATCGCCGACCGCCTGCAGAAGCGTTCGAT
CGGTTTTGGCGCGCATGTTGCCGATCCCGACAAGCGCAAGGTCGGCGAACTGCTCCAGAAGGCAGAGCCCGAGGATCTCC
TCAAGTTCGGCCTGATCCCGGAATTCGTCGGCCGTCTCCCGGTGATCGCGACGCTCAACGACCTCGACATCGAGGCGCTG
GTCAAGATCCTCAAGGAGCCCAAGAACGCACTGGTAAAGCAGTACGCCAAGCTCTTCGAGCTTGAAGACGTCACCCTGAC
CTTCACCGACGACGCTCTCGAGGCGATCGCCAAGAAGGCCATTGAACGCAAGACCGGCGCGCGCGGTCTGCGTTCGATCG
TCGAAGGCCTTCTGCTCGACACCATGTTCGACGTGCCGACCGAAAGCGACATTGCCGAAATCGTCGTCGACAAGGATGTC
GTCGAAGGTCGCAAGGAACCCGTCCGTGTCCTCAAGGGCAAGGAAGAAGCGGCCTGA

Upstream 100 bases:

>100_bases
TAAGGACCTGTTACCTGTTTTCGAGTCCGGTTGATTAATGCCCTTGCGGTAGTAGGATGATCGGGCCCGCCTCTCGTGGA
GAGGCGCCTGGGATGGAAGA

Downstream 100 bases:

>100_bases
ACGCTCGCTTCATCGGAACATGAAAAGGGCGGGTGCCGAAAGGCGCCCGCCCTTTTTCGTTGCCCATCCCGTGCAAAATC
TACTTCGTCATTGCGAGCGG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTKLSGSDTKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCNDIIREETKAGIAGKKDGGVPTPRDIFETLNDYVIG
QDRAKRVLSVAVHNHYKRLKHSGKGGDVELSKSNILLVGPTGSGKTLLAQTLAKTFDVPFTMADATTLTEAGYVGEDVEN
IILKLLQASDYNVEKAQHGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLMEGTTASVPPQGGRKHPQQEFLQVDT
TNILFICGGAFAGLEKIIADRLQKRSIGFGAHVADPDKRKVGELLQKAEPEDLLKFGLIPEFVGRLPVIATLNDLDIEAL
VKILKEPKNALVKQYAKLFELEDVTLTFTDDALEAIAKKAIERKTGARGLRSIVEGLLLDTMFDVPTESDIAEIVVDKDV
VEGRKEPVRVLKGKEEAA

Sequences:

>Translated_418_residues
MTKLSGSDTKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCNDIIREETKAGIAGKKDGGVPTPRDIFETLNDYVIG
QDRAKRVLSVAVHNHYKRLKHSGKGGDVELSKSNILLVGPTGSGKTLLAQTLAKTFDVPFTMADATTLTEAGYVGEDVEN
IILKLLQASDYNVEKAQHGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLMEGTTASVPPQGGRKHPQQEFLQVDT
TNILFICGGAFAGLEKIIADRLQKRSIGFGAHVADPDKRKVGELLQKAEPEDLLKFGLIPEFVGRLPVIATLNDLDIEAL
VKILKEPKNALVKQYAKLFELEDVTLTFTDDALEAIAKKAIERKTGARGLRSIVEGLLLDTMFDVPTESDIAEIVVDKDV
VEGRKEPVRVLKGKEEAA
>Mature_417_residues
TKLSGSDTKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCNDIIREETKAGIAGKKDGGVPTPRDIFETLNDYVIGQ
DRAKRVLSVAVHNHYKRLKHSGKGGDVELSKSNILLVGPTGSGKTLLAQTLAKTFDVPFTMADATTLTEAGYVGEDVENI
ILKLLQASDYNVEKAQHGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLMEGTTASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLEKIIADRLQKRSIGFGAHVADPDKRKVGELLQKAEPEDLLKFGLIPEFVGRLPVIATLNDLDIEALV
KILKEPKNALVKQYAKLFELEDVTLTFTDDALEAIAKKAIERKTGARGLRSIVEGLLLDTMFDVPTESDIAEIVVDKDVV
EGRKEPVRVLKGKEEAA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=325, Percent_Identity=55.0769230769231, Blast_Score=332, Evalue=3e-91,
Organism=Escherichia coli, GI1786642, Length=419, Percent_Identity=69.6897374701671, Blast_Score=590, Evalue=1e-170,
Organism=Escherichia coli, GI1790366, Length=104, Percent_Identity=43.2692307692308, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=50, Blast_Score=291, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI71982905, Length=316, Percent_Identity=49.6835443037975, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI71988663, Length=403, Percent_Identity=39.2059553349876, Blast_Score=252, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=264, Percent_Identity=39.3939393939394, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=437, Percent_Identity=37.7574370709382, Blast_Score=263, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=52.5157232704402, Blast_Score=321, Evalue=6e-88,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=52.5157232704402, Blast_Score=321, Evalue=7e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_NOVAD (Q2G3T4)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_498323.1
- ProteinModelPortal:   Q2G3T4
- STRING:   Q2G3T4
- GeneID:   3916667
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_3054
- NMPDR:   fig|48935.1.peg.1495
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q2G3T4
- ProtClustDB:   PRK05342
- BioCyc:   NARO279238:SARO_3054-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: 3.4.21.92

Molecular weight: Translated: 45609; Mature: 45478

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLSGSDTKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCNDIIREETKAGIAGKK
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGGVPTPRDIFETLNDYVIGQDRAKRVLSVAVHNHYKRLKHSGKGGDVELSKSNILLVGP
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEC
TGSGKTLLAQTLAKTFDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVEKAQHGI
CCCCHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCE
VYIDEIDKISRKAENPSITRDVSGEGVQQALLKLMEGTTASVPPQGGRKHPQQEFLQVDT
EEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCC
TNILFICGGAFAGLEKIIADRLQKRSIGFGAHVADPDKRKVGELLQKAEPEDLLKFGLIP
CCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCH
EFVGRLPVIATLNDLDIEALVKILKEPKNALVKQYAKLFELEDVTLTFTDDALEAIAKKA
HHHCCCCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHH
IERKTGARGLRSIVEGLLLDTMFDVPTESDIAEIVVDKDVVEGRKEPVRVLKGKEEAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKLSGSDTKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCNDIIREETKAGIAGKK
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGGVPTPRDIFETLNDYVIGQDRAKRVLSVAVHNHYKRLKHSGKGGDVELSKSNILLVGP
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEC
TGSGKTLLAQTLAKTFDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVEKAQHGI
CCCCHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCE
VYIDEIDKISRKAENPSITRDVSGEGVQQALLKLMEGTTASVPPQGGRKHPQQEFLQVDT
EEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCC
TNILFICGGAFAGLEKIIADRLQKRSIGFGAHVADPDKRKVGELLQKAEPEDLLKFGLIP
CCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCH
EFVGRLPVIATLNDLDIEALVKILKEPKNALVKQYAKLFELEDVTLTFTDDALEAIAKKA
HHHCCCCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHH
IERKTGARGLRSIVEGLLLDTMFDVPTESDIAEIVVDKDVVEGRKEPVRVLKGKEEAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA