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The map label for this gene is pphA [C]

Identifier: 87201052

GI number: 87201052

Start: 3254703

End: 3255509

Strand: Direct

Name: pphA [C]

Synonym: Saro_3040

Alternate gene names: 87201052

Gene position: 3254703-3255509 (Clockwise)

Preceding gene: 87201050

Following gene: 87201053

Centisome position: 91.38

GC content: 65.18

Gene sequence:

>807_bases
ATGTTCAGCAAGCTCCGCTCCCTGTTTTCCCCGGAAAGTCCTGCGCCCCGCGCTCCGGAACCCCAGGCCGAATACCGTGT
CCCTGCCGGCCGGCGGGTCTATGCGATCGGCGACATTCACGGGCGCCTGGATCTTTTCGAACAAGTGCTGGCGCTGATCG
ACGAGGACGACGCACGTCGCGGACCGGCGGAAACGACTCTCGTCCTGCTGGGCGATCTGATCGACCGGGGCCCGGACAGT
CGCGGCGTCGTCGAACGCGCGATGGAACTGGCGCAAACCGGGCGGGTGCGCATTCTTGCCGGCAACCACGAGGAAATGCT
GCTCGACAGCTTCGGCAACGAAGAGGTGCTGCGCCATTTCCTGCGCCACGGCGGGAAGGAAACGCTGTTCAGCTACGGGC
TGGCGATGGAAGACTATGCGAAGTCGAACCTCCCGGACCTTCAGGAACGGCTACCCACGCTCGTGCCGCAATCACATCTG
GACTTCATGCGCCGGATGGAGAACCAGGTCGTCGTCGGCGACTACCTGTTCGTTCATGCCGGCATCCGTCCCGGCGTGCC
GCTGGCCGAGCAGGCCGTATCGGACATGCGCTGGATCCGCCGCGACTTCCTCGACTTTGCCGAAGACCACGGCTGCATGG
TGGTCCACGGCCACACGATCACCGACGAGCCGGCGCTGCTCCACAACCGCATCGGCATCGATACCGGCGCCTTCGCTTCG
GGCCGGCTGACCGCGCTCGGCATCGAGGGCGCTGAGCGATGGATTCTGTCGGCCAACATCGCTCGCCAGGCGAACGACAC
GAACTGA

Upstream 100 bases:

>100_bases
GATTGCCATTTGTGTCTTTTGCGCACCATTCCCCCGCCATCGGGCCAAAGGTGTTGAATAGCCGGAGCCGCGCAGCCATA
TCGCACCGTCAAGAGGGTCC

Downstream 100 bases:

>100_bases
TCCTGCGGGGGTCGGACGCGCACGACGCCCCGCCTCGTTCCGCACTGCAGCAACTTTTTTGACCTGTTGCCGCAGTGCAA
CTACTTGGTGAAGATTGCCG

Product: metallophosphoesterase

Products: A Protein; Orthophosphate. [C]

Alternate protein names: Serine/Threonine Protein Phosphatase; Bis(5Nucleosyl)-Tetraphosphatase ApaH; Serine/Threonine Protein Phosphatase Family Protein; Ser/Thr Protein Phosphatase Family Protein; Serine/Threonine Specific Protein Phosphatase Protein; Serine/Threonine Protein Phosphatase I; Diadenosine Tetraphosphatase; Diadenosine Tetraphosphatase-Like Protein; Phosphatase; Serinethreonine Protein Phosphatase; Phosphoprotein Phosphatase; Serine/Threonine Specific Protein Phosphatase; Calcineurin-Like Phosphoesterase; Protein Serine-Threonine Phosphatase; Bis(5-Nucleosyl)-Tetraphosphatase; Serine/Threonine Protein Phosphatase Protein; Protein Phosphatase; Serine/Threonine-Protein Phosphatase

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MFSKLRSLFSPESPAPRAPEPQAEYRVPAGRRVYAIGDIHGRLDLFEQVLALIDEDDARRGPAETTLVLLGDLIDRGPDS
RGVVERAMELAQTGRVRILAGNHEEMLLDSFGNEEVLRHFLRHGGKETLFSYGLAMEDYAKSNLPDLQERLPTLVPQSHL
DFMRRMENQVVVGDYLFVHAGIRPGVPLAEQAVSDMRWIRRDFLDFAEDHGCMVVHGHTITDEPALLHNRIGIDTGAFAS
GRLTALGIEGAERWILSANIARQANDTN

Sequences:

>Translated_268_residues
MFSKLRSLFSPESPAPRAPEPQAEYRVPAGRRVYAIGDIHGRLDLFEQVLALIDEDDARRGPAETTLVLLGDLIDRGPDS
RGVVERAMELAQTGRVRILAGNHEEMLLDSFGNEEVLRHFLRHGGKETLFSYGLAMEDYAKSNLPDLQERLPTLVPQSHL
DFMRRMENQVVVGDYLFVHAGIRPGVPLAEQAVSDMRWIRRDFLDFAEDHGCMVVHGHTITDEPALLHNRIGIDTGAFAS
GRLTALGIEGAERWILSANIARQANDTN
>Mature_268_residues
MFSKLRSLFSPESPAPRAPEPQAEYRVPAGRRVYAIGDIHGRLDLFEQVLALIDEDDARRGPAETTLVLLGDLIDRGPDS
RGVVERAMELAQTGRVRILAGNHEEMLLDSFGNEEVLRHFLRHGGKETLFSYGLAMEDYAKSNLPDLQERLPTLVPQSHL
DFMRRMENQVVVGDYLFVHAGIRPGVPLAEQAVSDMRWIRRDFLDFAEDHGCMVVHGHTITDEPALLHNRIGIDTGAFAS
GRLTALGIEGAERWILSANIARQANDTN

Specific function: Plays A Key Role In Signaling Protein Misfolding Via The Cpxr/Cpxa Transducing System. It Also Modulates The Phosphorylated Status Of Many Phosphoproteins In E. coli, Some Of Which Acting As Major Chaperones. Has Been Shown, In Vitro, To Act On Ser, Thr A

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.16 [C]

Molecular weight: Translated: 29915; Mature: 29915

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSKLRSLFSPESPAPRAPEPQAEYRVPAGRRVYAIGDIHGRLDLFEQVLALIDEDDARR
CCHHHHHHHCCCCCCCCCCCCCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCC
GPAETTLVLLGDLIDRGPDSRGVVERAMELAQTGRVRILAGNHEEMLLDSFGNEEVLRHF
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCHHHHHHH
LRHGGKETLFSYGLAMEDYAKSNLPDLQERLPTLVPQSHLDFMRRMENQVVVGDYLFVHA
HHCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEEEC
GIRPGVPLAEQAVSDMRWIRRDFLDFAEDHGCMVVHGHTITDEPALLHNRIGIDTGAFAS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCC
GRLTALGIEGAERWILSANIARQANDTN
CCEEEEECCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFSKLRSLFSPESPAPRAPEPQAEYRVPAGRRVYAIGDIHGRLDLFEQVLALIDEDDARR
CCHHHHHHHCCCCCCCCCCCCCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCC
GPAETTLVLLGDLIDRGPDSRGVVERAMELAQTGRVRILAGNHEEMLLDSFGNEEVLRHF
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCHHHHHHH
LRHGGKETLFSYGLAMEDYAKSNLPDLQERLPTLVPQSHLDFMRRMENQVVVGDYLFVHA
HHCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEEEC
GIRPGVPLAEQAVSDMRWIRRDFLDFAEDHGCMVVHGHTITDEPALLHNRIGIDTGAFAS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCC
GRLTALGIEGAERWILSANIARQANDTN
CCEEEEECCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Phosphoprotein; H2O [C]

Specific reaction: A Phosphoprotein + H2O = A Protein + Orthophosphate. [C]

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA