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The map label for this gene is proA [H]

Identifier: 87200830

GI number: 87200830

Start: 3040856

End: 3041596

Strand: Direct

Name: proA [H]

Synonym: Saro_2817

Alternate gene names: 87200830

Gene position: 3040856-3041596 (Clockwise)

Preceding gene: 87200819

Following gene: 87200831

Centisome position: 85.38

GC content: 66.53

Gene sequence:

>741_bases
ATGCATTGGTTCCCTGCGGTCCGCAGTTCCATGGAACGCGCGAAGATCTTTCATCGGGAGCCGGAAATGTCGGGTATCGT
CGTCCAGAACATCGAGCGTGCCGATCCAGCCGTGATCGACGGCCTTGCCGCCTGCGGCGTCGCCACCGTCCACGAAGCGC
AGGGGCGCACCGGCCTCCTCGCTTCCTACATGCGCCCGATCTATCGCGGCGCGCGCATCGCTGGCTCCGCCGTCACCATC
AGCGCCCCTCCGGGCGACAACTGGATGGTCCACGTCGCGATCGAACAGCTCCAGGCCGGTGACATCCTGCTGCTCGGCCC
CACTTCGCCTTGCGAGGACGGCTACTTCGGCGACCTTCTCGCCACCAGCGCACAGGCACGCGGTTGCCGCGGCCTCGTGA
TCGACGCCGGCGTGCGCGACGTGCGCGACCTCACCGAAATGCAGTTCCCCGTCTGGTCCAAGGCAATCTACGCGCAGGGT
ACGGTGAAGAACACGCTCGGCAGCGTCAACGTGCCCGTGGTCTGCGCCAACGCGCTGGTGAACCCCGGCGACGTGATCGT
GGCCGACGACGACGGCGTGTGCGTGGTCCCGCGTGAAAAGGCTGCCGAAGTGCTGAAGGCCGCGCAGGCCCGCGAAGCCA
ACGAAGGCGAAAAGCGCGAGAAGCTCGCCGCCGGCGTCCTCGGCCTCGACATGTACAAGATGCGCGAACGCCTCGAGAAG
GAAGGCCTGAAGTACGTCTGA

Upstream 100 bases:

>100_bases
GTGGCGCACCGTTGCGGCGAAGGCGGCGATGTGCCTGATGTTGATCGCGTGCAGGGCCATGCCTGATCACTTAGCATTTC
CTTATGGGCCGGGGCAAACA

Downstream 100 bases:

>100_bases
GGACAGGCGGGGCATCAATCGCCCCTCCACCGTTCGTGTCGAGCGAAGTCGAGACACGGGCGCGCAGGTGTCTCGACTTC
CGGCCTCCCGGGCCGGAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MHWFPAVRSSMERAKIFHREPEMSGIVVQNIERADPAVIDGLAACGVATVHEAQGRTGLLASYMRPIYRGARIAGSAVTI
SAPPGDNWMVHVAIEQLQAGDILLLGPTSPCEDGYFGDLLATSAQARGCRGLVIDAGVRDVRDLTEMQFPVWSKAIYAQG
TVKNTLGSVNVPVVCANALVNPGDVIVADDDGVCVVPREKAAEVLKAAQAREANEGEKREKLAAGVLGLDMYKMRERLEK
EGLKYV

Sequences:

>Translated_246_residues
MHWFPAVRSSMERAKIFHREPEMSGIVVQNIERADPAVIDGLAACGVATVHEAQGRTGLLASYMRPIYRGARIAGSAVTI
SAPPGDNWMVHVAIEQLQAGDILLLGPTSPCEDGYFGDLLATSAQARGCRGLVIDAGVRDVRDLTEMQFPVWSKAIYAQG
TVKNTLGSVNVPVVCANALVNPGDVIVADDDGVCVVPREKAAEVLKAAQAREANEGEKREKLAAGVLGLDMYKMRERLEK
EGLKYV
>Mature_246_residues
MHWFPAVRSSMERAKIFHREPEMSGIVVQNIERADPAVIDGLAACGVATVHEAQGRTGLLASYMRPIYRGARIAGSAVTI
SAPPGDNWMVHVAIEQLQAGDILLLGPTSPCEDGYFGDLLATSAQARGCRGLVIDAGVRDVRDLTEMQFPVWSKAIYAQG
TVKNTLGSVNVPVVCANALVNPGDVIVADDDGVCVVPREKAAEVLKAAQAREANEGEKREKLAAGVLGLDMYKMRERLEK
EGLKYV

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 26442; Mature: 26442

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHWFPAVRSSMERAKIFHREPEMSGIVVQNIERADPAVIDGLAACGVATVHEAQGRTGLL
CCCCHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCHHHHHHHHHHCHHHHHHCCCCHHHH
ASYMRPIYRGARIAGSAVTISAPPGDNWMVHVAIEQLQAGDILLLGPTSPCEDGYFGDLL
HHHHHHHHHCCEECCCEEEEECCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCHHHH
ATSAQARGCRGLVIDAGVRDVRDLTEMQFPVWSKAIYAQGTVKNTLGSVNVPVVCANALV
HHHHHCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHCCCCHHHHCCCCCCCEEECCCCC
NPGDVIVADDDGVCVVPREKAAEVLKAAQAREANEGEKREKLAAGVLGLDMYKMRERLEK
CCCCEEEECCCCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGLKYV
CCCCCC
>Mature Secondary Structure
MHWFPAVRSSMERAKIFHREPEMSGIVVQNIERADPAVIDGLAACGVATVHEAQGRTGLL
CCCCHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCHHHHHHHHHHCHHHHHHCCCCHHHH
ASYMRPIYRGARIAGSAVTISAPPGDNWMVHVAIEQLQAGDILLLGPTSPCEDGYFGDLL
HHHHHHHHHCCEECCCEEEEECCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCHHHH
ATSAQARGCRGLVIDAGVRDVRDLTEMQFPVWSKAIYAQGTVKNTLGSVNVPVVCANALV
HHHHHCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHCCCCHHHHCCCCCCCEEECCCCC
NPGDVIVADDDGVCVVPREKAAEVLKAAQAREANEGEKREKLAAGVLGLDMYKMRERLEK
CCCCEEEECCCCEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EGLKYV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]