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The map label for this gene is dsbD [H]

Identifier: 87200804

GI number: 87200804

Start: 3012112

End: 3014172

Strand: Direct

Name: dsbD [H]

Synonym: Saro_2791

Alternate gene names: 87200804

Gene position: 3012112-3014172 (Clockwise)

Preceding gene: 87200801

Following gene: 87200812

Centisome position: 84.57

GC content: 70.06

Gene sequence:

>2061_bases
ATGCCGATACGCGAATTGGTCGGGATCAAGACCCGCCTCGATCCTCTCGGGCGCATCATAGCGATGCTTGTGACAGCGAT
GTGTCTGTCGCTTCTCGCGTGGCTTTCCCCCGTCCATGCCGCGCCCAACCGCATGACCGCATCGCTGGTCGCGGAGGGCC
CGGTCCGCCCCGGAGAAACGGTCACGCTCGCCCTGCTCATGCAGCCCGAAAAGGGGTGGCACGGCTACTGGTCCAACCCG
GGCGACGCCGGCTTCGGCCTGACCGTCGAGTGGACCCTGCCGGCGGGCGTGACCGCAGGCGATATGCAGTTCCCTGTCCC
GCAGACGCTCGTCGTTCAAGGGCTGATGAACCACGTCTACGAGCATGACTATGCTGTCCTCGTGCCGCTCAAGGTGCCTT
CCAGCGCCCGTTCGGGAACGCTCCTGCCAATCAGGGTCAAGGCCCAGTGGCTCGTCTGCACCGAAACGATCTGCGTGCCC
GAACGCGCCGAATTGCAAGGCGCGGTTAGCGTCGGCACCGGCCCCGCCGACCCGCGCTTCGAAGGATGGCGCGCCGCCAT
GCCAGCCCCGCTCGATCGTCCGGGCGCATTTGCGCTCGAAAGCGGCACGCTGCGCCTCGCCCTCCCGTTCCCGGCCACCG
CGCCGCTCGATGCGCCGCACCTTTTCCTCAAGACCGAACGCGTGGTCGATTACGCCGCGCCGCAACGCTTCTTCCGCCAG
GGCGACACACTTGTCGTCGAAGTTCCGCTGGCCAAGTCGCCCGCCACCGCCTCAAGGCTCGAAGGCGTCCTGGCGATGGG
CAGGGACGCGGGCGGCATTGCCTTCGCCGCCGAGCCCGGCACCGTGCCGAAGGGCGGCACGCAAGTAGGCGCTGGCGCCT
TCTCCGCCTCGGTCCTCGCGCTTGCTCTTGCCGGAGCGTTCCTCGGCGGGCTGATCCTCAACGTGATGCCCTGCGTCTTC
CCCATACTCAGCCTCAAGGCCCTCGCTCTGGCCCGGGGCAACGCGCATGAAGCCCACAAGGAGGGCCTGGCCTATACCGC
CGGCGTCGTCCTCGCGTGCCTCCTTCTGGGCGGCGTGATGCTGGCCCTGCGCGCAGGCGGAGAACAGGTCGGATGGGCGT
TCCAGTTGCAGGAACCGGGCGTCGTCGCCGTCCTCATGCTCCTGGCGGTTGCGATCACGGCAAACTTCGCGGGGCTCTAC
GAACTTCCCGGTCTTTCGGTCGAGCGCGGTGCGGGCGCGACCGGGGCGTTCGGCACGGGCCTGCTTGCCGCCTTCGTCGC
CACGCCCTGCACCGGGCCGTTCATGGCCGCCGCCATGGGCGCGGCGCTCGTCCTGCCGGCGTGGGCAGCGCTAGGCGTCT
TCGCGGCGCTGGGGCTAGGCCTCGCCCTGCCGTTCCTGCTCCTGGGCTTCGTGCCGGCCCTGCGCCGCCTTCTGCCCAAG
CCCGGCAAGTGGATGGAGCGCTTCCGCCGCTGGATGGCGCTGCCGATGGGCCTCACCGCGCTGGCGCTGGGCTGGCTGGC
ATGGCGCGTGGGCGGGGCGACCTTCACCGTCGTTCTGGTTGCAATCGCCGTGGTGTTGCTCGGCGCACTTGCGGCTGTCG
GGGTGACGCAGCGCAAGGGCCTGCCGATCGGCAGGCTCATGGCCCTGGCTGCCCTGATCGCCGTCGGCGGCGTGATCGGC
CTGCCCCCGCCCGCGCAGACCGCCGCCAGCGAAGGTGGCCTGCTCGAGGCCCGGCCCTTCTCGGAAGCCGCGCTGGCCGA
GGCCCGCAAGGCAGGAAAGCCCGTCTTCGCCTACTTCACCGCCGACTGGTGCCTGTCCTGCAAGGTCAACGAGAGCACCT
CGATCGAGCGCGAGAGCACCCGCGCGGCGTTCGAGAAGGCCGGCGTCGTCGTCCTTGTCGGCGACTGGACCCGGCGCGAC
CCGGCGATCACCCGGTTCCTCACCGCGCAGGGCGTCGCAGGCGTGCCGCTATATATGTGGTATCCTGCCGGCGGCGCCGA
GCCCCGCCAGCTTCCGCAGGTCCTCACGCCCGACATGCTGGCCGCACTGCCGGGGCAATAG

Upstream 100 bases:

>100_bases
GGACTCAGGCACAAGCCGATCGTAGGACGCCCCAAGAGCGCTACGCATGGCCCCGGCGGCGTTCCGGTTCAAGGGGCCTT
TTGGACCTGTGAAGCCCGAG

Downstream 100 bases:

>100_bases
TGCCCGCGCTTACAGGCTCTGCCCGTCGTCCACCGAAATGAACGTCCCCGTCACCTGACGCGATGCGTCAGAGGCGAAGA
ACAGCATCATGTCGTCCAGT

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MPIRELVGIKTRLDPLGRIIAMLVTAMCLSLLAWLSPVHAAPNRMTASLVAEGPVRPGETVTLALLMQPEKGWHGYWSNP
GDAGFGLTVEWTLPAGVTAGDMQFPVPQTLVVQGLMNHVYEHDYAVLVPLKVPSSARSGTLLPIRVKAQWLVCTETICVP
ERAELQGAVSVGTGPADPRFEGWRAAMPAPLDRPGAFALESGTLRLALPFPATAPLDAPHLFLKTERVVDYAAPQRFFRQ
GDTLVVEVPLAKSPATASRLEGVLAMGRDAGGIAFAAEPGTVPKGGTQVGAGAFSASVLALALAGAFLGGLILNVMPCVF
PILSLKALALARGNAHEAHKEGLAYTAGVVLACLLLGGVMLALRAGGEQVGWAFQLQEPGVVAVLMLLAVAITANFAGLY
ELPGLSVERGAGATGAFGTGLLAAFVATPCTGPFMAAAMGAALVLPAWAALGVFAALGLGLALPFLLLGFVPALRRLLPK
PGKWMERFRRWMALPMGLTALALGWLAWRVGGATFTVVLVAIAVVLLGALAAVGVTQRKGLPIGRLMALAALIAVGGVIG
LPPPAQTAASEGGLLEARPFSEAALAEARKAGKPVFAYFTADWCLSCKVNESTSIERESTRAAFEKAGVVVLVGDWTRRD
PAITRFLTAQGVAGVPLYMWYPAGGAEPRQLPQVLTPDMLAALPGQ

Sequences:

>Translated_686_residues
MPIRELVGIKTRLDPLGRIIAMLVTAMCLSLLAWLSPVHAAPNRMTASLVAEGPVRPGETVTLALLMQPEKGWHGYWSNP
GDAGFGLTVEWTLPAGVTAGDMQFPVPQTLVVQGLMNHVYEHDYAVLVPLKVPSSARSGTLLPIRVKAQWLVCTETICVP
ERAELQGAVSVGTGPADPRFEGWRAAMPAPLDRPGAFALESGTLRLALPFPATAPLDAPHLFLKTERVVDYAAPQRFFRQ
GDTLVVEVPLAKSPATASRLEGVLAMGRDAGGIAFAAEPGTVPKGGTQVGAGAFSASVLALALAGAFLGGLILNVMPCVF
PILSLKALALARGNAHEAHKEGLAYTAGVVLACLLLGGVMLALRAGGEQVGWAFQLQEPGVVAVLMLLAVAITANFAGLY
ELPGLSVERGAGATGAFGTGLLAAFVATPCTGPFMAAAMGAALVLPAWAALGVFAALGLGLALPFLLLGFVPALRRLLPK
PGKWMERFRRWMALPMGLTALALGWLAWRVGGATFTVVLVAIAVVLLGALAAVGVTQRKGLPIGRLMALAALIAVGGVIG
LPPPAQTAASEGGLLEARPFSEAALAEARKAGKPVFAYFTADWCLSCKVNESTSIERESTRAAFEKAGVVVLVGDWTRRD
PAITRFLTAQGVAGVPLYMWYPAGGAEPRQLPQVLTPDMLAALPGQ
>Mature_685_residues
PIRELVGIKTRLDPLGRIIAMLVTAMCLSLLAWLSPVHAAPNRMTASLVAEGPVRPGETVTLALLMQPEKGWHGYWSNPG
DAGFGLTVEWTLPAGVTAGDMQFPVPQTLVVQGLMNHVYEHDYAVLVPLKVPSSARSGTLLPIRVKAQWLVCTETICVPE
RAELQGAVSVGTGPADPRFEGWRAAMPAPLDRPGAFALESGTLRLALPFPATAPLDAPHLFLKTERVVDYAAPQRFFRQG
DTLVVEVPLAKSPATASRLEGVLAMGRDAGGIAFAAEPGTVPKGGTQVGAGAFSASVLALALAGAFLGGLILNVMPCVFP
ILSLKALALARGNAHEAHKEGLAYTAGVVLACLLLGGVMLALRAGGEQVGWAFQLQEPGVVAVLMLLAVAITANFAGLYE
LPGLSVERGAGATGAFGTGLLAAFVATPCTGPFMAAAMGAALVLPAWAALGVFAALGLGLALPFLLLGFVPALRRLLPKP
GKWMERFRRWMALPMGLTALALGWLAWRVGGATFTVVLVAIAVVLLGALAAVGVTQRKGLPIGRLMALAALIAVGGVIGL
PPPAQTAASEGGLLEARPFSEAALAEARKAGKPVFAYFTADWCLSCKVNESTSIERESTRAAFEKAGVVVLVGDWTRRDP
AITRFLTAQGVAGVPLYMWYPAGGAEPRQLPQVLTPDMLAALPGQ

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=531, Percent_Identity=25.0470809792844, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 71413; Mature: 71282

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRELVGIKTRLDPLGRIIAMLVTAMCLSLLAWLSPVHAAPNRMTASLVAEGPVRPGET
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCE
VTLALLMQPEKGWHGYWSNPGDAGFGLTVEWTLPAGVTAGDMQFPVPQTLVVQGLMNHVY
EEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
EHDYAVLVPLKVPSSARSGTLLPIRVKAQWLVCTETICVPERAELQGAVSVGTGPADPRF
HCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEEEEEECCCCHHHCCCEEEECCCCCCCCC
EGWRAAMPAPLDRPGAFALESGTLRLALPFPATAPLDAPHLFLKTERVVDYAAPQRFFRQ
CCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHC
GDTLVVEVPLAKSPATASRLEGVLAMGRDAGGIAFAAEPGTVPKGGTQVGAGAFSASVLA
CCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
LALAGAFLGGLILNVMPCVFPILSLKALALARGNAHEAHKEGLAYTAGVVLACLLLGGVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
LALRAGGEQVGWAFQLQEPGVVAVLMLLAVAITANFAGLYELPGLSVERGAGATGAFGTG
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHCCCCCEECCCCCCCCHHHH
LLAAFVATPCTGPFMAAAMGAALVLPAWAALGVFAALGLGLALPFLLLGFVPALRRLLPK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGKWMERFRRWMALPMGLTALALGWLAWRVGGATFTVVLVAIAVVLLGALAAVGVTQRKG
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHCCC
LPIGRLMALAALIAVGGVIGLPPPAQTAASEGGLLEARPFSEAALAEARKAGKPVFAYFT
CCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEE
ADWCLSCKVNESTSIERESTRAAFEKAGVVVLVGDWTRRDPAITRFLTAQGVAGVPLYMW
ECEEEEEECCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEE
YPAGGAEPRQLPQVLTPDMLAALPGQ
ECCCCCCHHHHHHHCCCHHHHHCCCC
>Mature Secondary Structure 
PIRELVGIKTRLDPLGRIIAMLVTAMCLSLLAWLSPVHAAPNRMTASLVAEGPVRPGET
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCE
VTLALLMQPEKGWHGYWSNPGDAGFGLTVEWTLPAGVTAGDMQFPVPQTLVVQGLMNHVY
EEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
EHDYAVLVPLKVPSSARSGTLLPIRVKAQWLVCTETICVPERAELQGAVSVGTGPADPRF
HCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEEEEEECCCCHHHCCCEEEECCCCCCCCC
EGWRAAMPAPLDRPGAFALESGTLRLALPFPATAPLDAPHLFLKTERVVDYAAPQRFFRQ
CCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHC
GDTLVVEVPLAKSPATASRLEGVLAMGRDAGGIAFAAEPGTVPKGGTQVGAGAFSASVLA
CCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
LALAGAFLGGLILNVMPCVFPILSLKALALARGNAHEAHKEGLAYTAGVVLACLLLGGVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
LALRAGGEQVGWAFQLQEPGVVAVLMLLAVAITANFAGLYELPGLSVERGAGATGAFGTG
HHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHCCCCCEECCCCCCCCHHHH
LLAAFVATPCTGPFMAAAMGAALVLPAWAALGVFAALGLGLALPFLLLGFVPALRRLLPK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGKWMERFRRWMALPMGLTALALGWLAWRVGGATFTVVLVAIAVVLLGALAAVGVTQRKG
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHCCC
LPIGRLMALAALIAVGGVIGLPPPAQTAASEGGLLEARPFSEAALAEARKAGKPVFAYFT
CCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEEECCCCHHHHHHHHHHCCCCEEEEEE
ADWCLSCKVNESTSIERESTRAAFEKAGVVVLVGDWTRRDPAITRFLTAQGVAGVPLYMW
ECEEEEEECCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEE
YPAGGAEPRQLPQVLTPDMLAALPGQ
ECCCCCCHHHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]