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The map label for this gene is gcp

Identifier: 87200798

GI number: 87200798

Start: 3005420

End: 3006472

Strand: Reverse

Name: gcp

Synonym: Saro_2785

Alternate gene names: 87200798

Gene position: 3006472-3005420 (Counterclockwise)

Preceding gene: 87200802

Following gene: 87200797

Centisome position: 84.41

GC content: 68.0

Gene sequence:

>1053_bases
ATGGCCCTGATCCTTGGCATAGAATCCAGCTGCGATGAAACCGCCGCCGCGGTGATCGACAGCAATGGCGCGTCGCTCGA
AGCGCGCATCGTGGCGCAGCGCATCGCCTCGCAGGACGAAGCGCATCGACCCTATGGCGGCGTCGTTCCGGAAATCGCGG
CGCGCGCGCACGCCGAAGTGCTCAGTCCGATGATCGCGGCGGTGCTGGCCGACGCGGGGATCGGGCTGGACGACCTCGAT
GCCATCGCCGCGACCGCGGGGCCGGGGTTGATCGGCGGCGTCATGGTCGGTCTCGTTACCGGAAAGGCGCTGGCCATGGC
GGCGGACAAGCCGCTGATCGCGGTCAACCACCTGGAAGGCCACGCGCTTTCGCCGCGACTGGCCGAACCCTCGTTGCAAT
ACCCCTACCTGTTGCTGCTGGTTTCGGGCGGACATTGCCAGATCCTGGAAGTTGCGGGGGTCGGGCAGTTCCGCCGCCTT
GCCACCACCATCGACGATGCCTTGGGCGAAGCGTTCGACAAGACCGCGAAGATCCTCGGCCTCGGCTATCCAGGTGGGCC
GGCGGTGGAACGGATGGCGCGAGAGGGCAACCCCAAGGCCGTGCCCCTGCCGCGCCCGCTGGTCGGCAGCGGGGAGCCGC
ACTTCTCGTTCGCGGGCCTGAAGAGCGCGGTCATGCGGGCGAAGGATGCCGGTGTTCACGGGGACGCCGACATCGCCGCT
TCATTCCAGCAGGCGGCGATAGATTGCGTGATCGATCGCACCCGCATCGCGCTTGAGACTGCTTCTCCGGGCATGACGGC
GCTGGTGGTGGCTGGAGGCGTCGCCGCCAATGCCGCCTTGCGTGGCGCGCTGGAAGGACTGGCGGAGAGCCACGGGCTTT
CGCTGGTCGCGCCGCCGCCGAAACTGTGCACAGACAACGCTGCGATGATTGGTTGGGCTGGCGCGGAACGCCTTGCTCTG
GGATATGTCGATCCACTTGACGTGGCGGCGCGTCCGCGCTGGCCGCTCGACGAGAACGCCGCGCCGGTGCGCGGAGCAGG
GGTAAAGGCATGA

Upstream 100 bases:

>100_bases
GGGGAGAGCGGCGGGTGCCCAGCTTCAGGGGCCTTTGCGGAGCTTGGTTGTTCATGCGCCGCTTGCCGTAAACGGGATTA
TCTCTAGAGGAAAGCGCCAC

Downstream 100 bases:

>100_bases
CCTTCGAGGTGGGCGTCGTCGGCGCGGGCGCATGGGGCACGGCGCTGGCGCAGATGCTATCCAGCGACGGGCGCGAGGTC
CTGCTGTGGGCGCGCGAGAG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MALILGIESSCDETAAAVIDSNGASLEARIVAQRIASQDEAHRPYGGVVPEIAARAHAEVLSPMIAAVLADAGIGLDDLD
AIAATAGPGLIGGVMVGLVTGKALAMAADKPLIAVNHLEGHALSPRLAEPSLQYPYLLLLVSGGHCQILEVAGVGQFRRL
ATTIDDALGEAFDKTAKILGLGYPGGPAVERMAREGNPKAVPLPRPLVGSGEPHFSFAGLKSAVMRAKDAGVHGDADIAA
SFQQAAIDCVIDRTRIALETASPGMTALVVAGGVAANAALRGALEGLAESHGLSLVAPPPKLCTDNAAMIGWAGAERLAL
GYVDPLDVAARPRWPLDENAAPVRGAGVKA

Sequences:

>Translated_350_residues
MALILGIESSCDETAAAVIDSNGASLEARIVAQRIASQDEAHRPYGGVVPEIAARAHAEVLSPMIAAVLADAGIGLDDLD
AIAATAGPGLIGGVMVGLVTGKALAMAADKPLIAVNHLEGHALSPRLAEPSLQYPYLLLLVSGGHCQILEVAGVGQFRRL
ATTIDDALGEAFDKTAKILGLGYPGGPAVERMAREGNPKAVPLPRPLVGSGEPHFSFAGLKSAVMRAKDAGVHGDADIAA
SFQQAAIDCVIDRTRIALETASPGMTALVVAGGVAANAALRGALEGLAESHGLSLVAPPPKLCTDNAAMIGWAGAERLAL
GYVDPLDVAARPRWPLDENAAPVRGAGVKA
>Mature_349_residues
ALILGIESSCDETAAAVIDSNGASLEARIVAQRIASQDEAHRPYGGVVPEIAARAHAEVLSPMIAAVLADAGIGLDDLDA
IAATAGPGLIGGVMVGLVTGKALAMAADKPLIAVNHLEGHALSPRLAEPSLQYPYLLLLVSGGHCQILEVAGVGQFRRLA
TTIDDALGEAFDKTAKILGLGYPGGPAVERMAREGNPKAVPLPRPLVGSGEPHFSFAGLKSAVMRAKDAGVHGDADIAAS
FQQAAIDCVIDRTRIALETASPGMTALVVAGGVAANAALRGALEGLAESHGLSLVAPPPKLCTDNAAMIGWAGAERLALG
YVDPLDVAARPRWPLDENAAPVRGAGVKA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=361, Percent_Identity=36.8421052631579, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI8923380, Length=306, Percent_Identity=30.0653594771242, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1789445, Length=338, Percent_Identity=44.6745562130178, Blast_Score=281, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17557464, Length=328, Percent_Identity=32.0121951219512, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=350, Percent_Identity=28, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320099, Length=366, Percent_Identity=29.7814207650273, Blast_Score=152, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6322891, Length=330, Percent_Identity=25.1515151515152, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129063, Length=348, Percent_Identity=35.0574712643678, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI21357207, Length=356, Percent_Identity=26.9662921348315, Blast_Score=118, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_NOVAD (Q2G4K2)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_498055.1
- ProteinModelPortal:   Q2G4K2
- SMR:   Q2G4K2
- STRING:   Q2G4K2
- MEROPS:   M22.001
- GeneID:   3916945
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_2785
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   Q2G4K2
- ProtClustDB:   PRK09604
- BioCyc:   NARO279238:SARO_2785-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35539; Mature: 35408

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALILGIESSCDETAAAVIDSNGASLEARIVAQRIASQDEAHRPYGGVVPEIAARAHAEV
CEEEEECCCCCCHHHHHEECCCCCCHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHH
LSPMIAAVLADAGIGLDDLDAIAATAGPGLIGGVMVGLVTGKALAMAADKPLIAVNHLEG
HHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEECCCCEEEEECCCC
HALSPRLAEPSLQYPYLLLLVSGGHCQILEVAGVGQFRRLATTIDDALGEAFDKTAKILG
CCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEE
LGYPGGPAVERMAREGNPKAVPLPRPLVGSGEPHFSFAGLKSAVMRAKDAGVHGDADIAA
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCHHHHH
SFQQAAIDCVIDRTRIALETASPGMTALVVAGGVAANAALRGALEGLAESHGLSLVAPPP
HHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCC
KLCTDNAAMIGWAGAERLALGYVDPLDVAARPRWPLDENAAPVRGAGVKA
CCCCCCCEEEEECCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALILGIESSCDETAAAVIDSNGASLEARIVAQRIASQDEAHRPYGGVVPEIAARAHAEV
EEEEECCCCCCHHHHHEECCCCCCHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHH
LSPMIAAVLADAGIGLDDLDAIAATAGPGLIGGVMVGLVTGKALAMAADKPLIAVNHLEG
HHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEECCCCEEEEECCCC
HALSPRLAEPSLQYPYLLLLVSGGHCQILEVAGVGQFRRLATTIDDALGEAFDKTAKILG
CCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEE
LGYPGGPAVERMAREGNPKAVPLPRPLVGSGEPHFSFAGLKSAVMRAKDAGVHGDADIAA
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCHHHHH
SFQQAAIDCVIDRTRIALETASPGMTALVVAGGVAANAALRGALEGLAESHGLSLVAPPP
HHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCC
KLCTDNAAMIGWAGAERLALGYVDPLDVAARPRWPLDENAAPVRGAGVKA
CCCCCCCEEEEECCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA