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The map label for this gene is gpsA

Identifier: 87200797

GI number: 87200797

Start: 3004428

End: 3005423

Strand: Reverse

Name: gpsA

Synonym: Saro_2784

Alternate gene names: 87200797

Gene position: 3005423-3004428 (Counterclockwise)

Preceding gene: 87200798

Following gene: 87200796

Centisome position: 84.38

GC content: 68.98

Gene sequence:

>996_bases
ATGACCTTCGAGGTGGGCGTCGTCGGCGCGGGCGCATGGGGCACGGCGCTGGCGCAGATGCTATCCAGCGACGGGCGCGA
GGTCCTGCTGTGGGCGCGCGAGAGCGAAGTGGTCCGCGAAATCAACGAGGACCGGCGCAATGGACCGTTCCTGCCTTCCG
CCTGTCTCAATCCGACGATCACCGCCACCGCAGACCTTGCCGACATGGCGCGCATCCCGGTCCTGCTGCTGGTGACGCCG
GCCCAGCATCTTGCGTCCGTTCTTGGCGGGATCGGGCGTGACGGTGGGGACGTGGTCCTGTGCTCAAAGGGGATCGAGGC
CGGAACCGGGCGGTTGATGGCCGACGTCGCCCGCGACGCGGCACCGGACGCGAGCATCGCCGTGCTTTCCGGCCCGACCT
TTGCGCATGAAGTGGCGGACGGGTTGCCGACGGCGGTTACCCTCGCCTGTGCCGGGGGAGAGGAACAGTGGCTGCGGCTT
TCGACCGCCATCGCCCGCCCGACGTTCCGTCCCTATTATTCGGACGACGTGACCGGGGCCGAGATCGGCGGCGCGGTGAA
GAACGTGCTGGCCATTGCCTGCGGCGTGGTCGAGGGACTGCGTCTCGGCCAGAACGCCCGGGCGGCGCTGATCAGCCGGG
GTTTCGCCGAAATGCAGCGTTTCGGGCTTGCGCTGGGGGCGCGGCCGAAAACATTGTCGGGGCTCTCGGGTTTGGGAGAC
CTGGTGTTGACATGTTCTTCCACTTCGAGCCGCAATTTCTCGCTCGGCAAGGCGCTGGGCGAGGGAGCAAGCGCAACGGC
CGTCATGGCCGACCGCGCGACGGTGGCCGAGGGGGCGTTCACCGCCCCGGTGCTTGCCGACCTTGCGCGCGGCCGCGGGA
TTTCCATGCCGATCGTCGAGGCCGTGGTCACGCTGCTCGAAGGCGCGGCACCGGCGCGCGAGGTGGTCGCGGGCCTGCTC
TCGCGTCCGTTGACCGCGGAAAATCCGCTTGTCTGA

Upstream 100 bases:

>100_bases
GCCTTGCTCTGGGATATGTCGATCCACTTGACGTGGCGGCGCGTCCGCGCTGGCCGCTCGACGAGAACGCCGCGCCGGTG
CGCGGAGCAGGGGTAAAGGC

Downstream 100 bases:

>100_bases
TCCCGTGCAGCGGACCGACCAGAAGGACATCGCCGCCCTTGCCAAGGGTGGGCGCACCAATTTTCTCGGCTTCCTGCTGC
GCCTGATGGCGCGCATACCC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTFEVGVVGAGAWGTALAQMLSSDGREVLLWARESEVVREINEDRRNGPFLPSACLNPTITATADLADMARIPVLLLVTP
AQHLASVLGGIGRDGGDVVLCSKGIEAGTGRLMADVARDAAPDASIAVLSGPTFAHEVADGLPTAVTLACAGGEEQWLRL
STAIARPTFRPYYSDDVTGAEIGGAVKNVLAIACGVVEGLRLGQNARAALISRGFAEMQRFGLALGARPKTLSGLSGLGD
LVLTCSSTSSRNFSLGKALGEGASATAVMADRATVAEGAFTAPVLADLARGRGISMPIVEAVVTLLEGAAPAREVVAGLL
SRPLTAENPLV

Sequences:

>Translated_331_residues
MTFEVGVVGAGAWGTALAQMLSSDGREVLLWARESEVVREINEDRRNGPFLPSACLNPTITATADLADMARIPVLLLVTP
AQHLASVLGGIGRDGGDVVLCSKGIEAGTGRLMADVARDAAPDASIAVLSGPTFAHEVADGLPTAVTLACAGGEEQWLRL
STAIARPTFRPYYSDDVTGAEIGGAVKNVLAIACGVVEGLRLGQNARAALISRGFAEMQRFGLALGARPKTLSGLSGLGD
LVLTCSSTSSRNFSLGKALGEGASATAVMADRATVAEGAFTAPVLADLARGRGISMPIVEAVVTLLEGAAPAREVVAGLL
SRPLTAENPLV
>Mature_330_residues
TFEVGVVGAGAWGTALAQMLSSDGREVLLWARESEVVREINEDRRNGPFLPSACLNPTITATADLADMARIPVLLLVTPA
QHLASVLGGIGRDGGDVVLCSKGIEAGTGRLMADVARDAAPDASIAVLSGPTFAHEVADGLPTAVTLACAGGEEQWLRLS
TAIARPTFRPYYSDDVTGAEIGGAVKNVLAIACGVVEGLRLGQNARAALISRGFAEMQRFGLALGARPKTLSGLSGLGDL
VLTCSSTSSRNFSLGKALGEGASATAVMADRATVAEGAFTAPVLADLARGRGISMPIVEAVVTLLEGAAPAREVVAGLLS
RPLTAENPLV

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=348, Percent_Identity=26.4367816091954, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI24307999, Length=348, Percent_Identity=25.8620689655172, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1790037, Length=326, Percent_Identity=42.638036809816, Blast_Score=224, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI32564399, Length=348, Percent_Identity=27.0114942528736, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17507425, Length=357, Percent_Identity=26.3305322128852, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193210136, Length=357, Percent_Identity=26.6106442577031, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32564403, Length=357, Percent_Identity=26.6106442577031, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320181, Length=348, Percent_Identity=28.1609195402299, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324513, Length=274, Percent_Identity=29.9270072992701, Blast_Score=99, Evalue=7e-22,
Organism=Drosophila melanogaster, GI22026922, Length=368, Percent_Identity=26.6304347826087, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17136202, Length=272, Percent_Identity=29.0441176470588, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136204, Length=272, Percent_Identity=29.0441176470588, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136200, Length=272, Percent_Identity=29.0441176470588, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281362270, Length=345, Percent_Identity=25.7971014492754, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45551945, Length=318, Percent_Identity=26.1006289308176, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24648969, Length=277, Percent_Identity=26.3537906137184, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_NOVAD (Q2G4K3)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_498054.1
- ProteinModelPortal:   Q2G4K3
- SMR:   Q2G4K3
- STRING:   Q2G4K3
- GeneID:   3916944
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_2784
- NMPDR:   fig|48935.1.peg.1026
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   AKGIEHG
- PhylomeDB:   Q2G4K3
- ProtClustDB:   PRK00094
- BioCyc:   NARO279238:SARO_2784-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 33812; Mature: 33681

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 187-187 BINDING 103-103 BINDING 103-103 BINDING 135-135 BINDING 251-251 BINDING 277-277

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFEVGVVGAGAWGTALAQMLSSDGREVLLWARESEVVREINEDRRNGPFLPSACLNPTI
CEEEEEEEECCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCHHHCCCCC
TATADLADMARIPVLLLVTPAQHLASVLGGIGRDGGDVVLCSKGIEAGTGRLMADVARDA
EEHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHC
APDASIAVLSGPTFAHEVADGLPTAVTLACAGGEEQWLRLSTAIARPTFRPYYSDDVTGA
CCCCCEEEEECCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCH
EIGGAVKNVLAIACGVVEGLRLGQNARAALISRGFAEMQRFGLALGARPKTLSGLSGLGD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCC
LVLTCSSTSSRNFSLGKALGEGASATAVMADRATVAEGAFTAPVLADLARGRGISMPIVE
EEEEECCCCCCCCHHHHHHCCCCCCEEEECCCHHHHCCCCHHHHHHHHHCCCCCCCHHHH
AVVTLLEGAAPAREVVAGLLSRPLTAENPLV
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TFEVGVVGAGAWGTALAQMLSSDGREVLLWARESEVVREINEDRRNGPFLPSACLNPTI
EEEEEEEECCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCCHHHCCCCC
TATADLADMARIPVLLLVTPAQHLASVLGGIGRDGGDVVLCSKGIEAGTGRLMADVARDA
EEHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHC
APDASIAVLSGPTFAHEVADGLPTAVTLACAGGEEQWLRLSTAIARPTFRPYYSDDVTGA
CCCCCEEEEECCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCH
EIGGAVKNVLAIACGVVEGLRLGQNARAALISRGFAEMQRFGLALGARPKTLSGLSGLGD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCC
LVLTCSSTSSRNFSLGKALGEGASATAVMADRATVAEGAFTAPVLADLARGRGISMPIVE
EEEEECCCCCCCCHHHHHHCCCCCCEEEECCCHHHHCCCCHHHHHHHHHCCCCCCCHHHH
AVVTLLEGAAPAREVVAGLLSRPLTAENPLV
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA