| Definition | Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome. |
|---|---|
| Accession | NC_007794 |
| Length | 3,561,584 |
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The map label for this gene is fabG [H]
Identifier: 87200523
GI number: 87200523
Start: 2714727
End: 2715464
Strand: Direct
Name: fabG [H]
Synonym: Saro_2510
Alternate gene names: 87200523
Gene position: 2714727-2715464 (Clockwise)
Preceding gene: 87200522
Following gene: 87200524
Centisome position: 76.22
GC content: 67.07
Gene sequence:
>738_bases ATGATGGACGATACTGATTTCACCGGCCGCCGCGTGCTGGTCGTGGGCGGCTCGAGCGGCATCGGCAACGGCATCGCGCA GGCATTCCGCGACCGGGGCGCCGAAGTCCACGTCTGGGGCACGCGCGCCAATGCCGCCGGCTATGACCCGGCCGAAGGCT CAGACCTTGCTGGCCTGGGCTATACCTGCGTCGATGTCGGCAGCCCCGATGCCATCGAAGCTGCTCCAGCCCCCTTCCCC GCGCTCGACGTGCTGGTCCTGTGCCAGGGCACCGTCGTCTACAAGCGCGGGGAATTCGAGCGCGAAGGATGGGACAAGGT CATGGCCGTCAACCTCGACAGCCTGATGCACTGTTCTCGCAAGTTCCGCCCGCAACTCGCTGAAACCGGCGGCTCAATCA TCATCGTCAGCTCGATCTCGGGGCTCAAGGCGAACATCGGAAACCCCGCGTATGCCGCCTCCAAGGCCGGGGCGATCAGC CTGACCAAGTCGCTCGGCCAAGCCTTTGCCGCCGACGGCATCCGCGTGAACGGCCTCGCCCCCGGCCTTGTGGATACCAA GCTGACCAAGGTGACGACCGCCCATCCCCAGCGCCTCGAAGGAGCGATCGCCAACATCCCGCAGCGGCGCATGGGCACGC CCGCGGACATGGCCGGCGCCGCGATCTTCCTTGCCTCCCCGCTCGCCTCCTACGTCACCGGCCATACACTCGTGGTCGAT GGCGGCCTCTCGCTCTGA
Upstream 100 bases:
>100_bases GCGAAGCCCCCGCCCTCATCCGAAGGCGGGGGCTTTTGCGTTCCGGCAGGTTGGCTACGCTGACCGGATGGAGTCGCGCA AAGCGACCGACAGGAGAGCG
Downstream 100 bases:
>100_bases AAGCCTGTACCATGCAGTTCGAACACTCCGACAAGGTCAAGAACCTCCTCGCCCGCCTCGAAGCCTTCATGGACGAGCAC ATCTACCCGGTCGAACAGGC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 245; Mature: 245
Protein sequence:
>245_residues MMDDTDFTGRRVLVVGGSSGIGNGIAQAFRDRGAEVHVWGTRANAAGYDPAEGSDLAGLGYTCVDVGSPDAIEAAPAPFP ALDVLVLCQGTVVYKRGEFEREGWDKVMAVNLDSLMHCSRKFRPQLAETGGSIIIVSSISGLKANIGNPAYAASKAGAIS LTKSLGQAFAADGIRVNGLAPGLVDTKLTKVTTAHPQRLEGAIANIPQRRMGTPADMAGAAIFLASPLASYVTGHTLVVD GGLSL
Sequences:
>Translated_245_residues MMDDTDFTGRRVLVVGGSSGIGNGIAQAFRDRGAEVHVWGTRANAAGYDPAEGSDLAGLGYTCVDVGSPDAIEAAPAPFP ALDVLVLCQGTVVYKRGEFEREGWDKVMAVNLDSLMHCSRKFRPQLAETGGSIIIVSSISGLKANIGNPAYAASKAGAIS LTKSLGQAFAADGIRVNGLAPGLVDTKLTKVTTAHPQRLEGAIANIPQRRMGTPADMAGAAIFLASPLASYVTGHTLVVD GGLSL >Mature_245_residues MMDDTDFTGRRVLVVGGSSGIGNGIAQAFRDRGAEVHVWGTRANAAGYDPAEGSDLAGLGYTCVDVGSPDAIEAAPAPFP ALDVLVLCQGTVVYKRGEFEREGWDKVMAVNLDSLMHCSRKFRPQLAETGGSIIIVSSISGLKANIGNPAYAASKAGAIS LTKSLGQAFAADGIRVNGLAPGLVDTKLTKVTTAHPQRLEGAIANIPQRRMGTPADMAGAAIFLASPLASYVTGHTLVVD GGLSL
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=36.0655737704918, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI32483357, Length=239, Percent_Identity=32.6359832635983, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI15277342, Length=167, Percent_Identity=38.3233532934132, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=30, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI19923817, Length=149, Percent_Identity=35.5704697986577, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=29.5081967213115, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=31.4410480349345, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.1204819277108, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=30.3643724696356, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI59889578, Length=153, Percent_Identity=32.6797385620915, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=28.2945736434109, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=34.412955465587, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=32.9317269076305, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=29.8387096774194, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=31.7829457364341, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=32.1138211382114, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=32.5670498084291, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=32.7800829875519, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=29.2490118577075, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI2367175, Length=149, Percent_Identity=34.2281879194631, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789057, Length=157, Percent_Identity=31.8471337579618, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1788459, Length=144, Percent_Identity=31.25, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=35.3174603174603, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=36.734693877551, Blast_Score=123, Evalue=9e-29, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=31.0756972111554, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=30.7984790874525, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=30.5220883534137, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=30.9160305343511, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=29.7709923664122, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=30.7116104868914, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=29.0076335877863, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=29.6747967479675, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=28.9473684210526, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=31.2977099236641, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=29.277566539924, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=30.6122448979592, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=27.8195488721804, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=27.6119402985075, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.8810408921933, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=29.277566539924, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17544670, Length=278, Percent_Identity=25.5395683453237, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=27.2, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=30.3030303030303, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=27.9693486590038, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=28.3524904214559, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=29.2490118577075, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=27.9850746268657, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=27.6515151515151, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=28.9156626506024, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI193207185, Length=147, Percent_Identity=32.6530612244898, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=28.3400809716599, Blast_Score=79, Evalue=7e-16, Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=33.1983805668016, Blast_Score=107, Evalue=9e-24, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=29.6747967479675, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=31.8367346938775, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=31.6, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=30.952380952381, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.6, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644337, Length=143, Percent_Identity=39.1608391608392, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=30.4347826086957, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=28.0769230769231, Blast_Score=68, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25254; Mature: 25254
Theoretical pI: Translated: 6.51; Mature: 6.51
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMDDTDFTGRRVLVVGGSSGIGNGIAQAFRDRGAEVHVWGTRANAAGYDPAEGSDLAGLG CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCC YTCVDVGSPDAIEAAPAPFPALDVLVLCQGTVVYKRGEFEREGWDKVMAVNLDSLMHCSR EEEEECCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCEEEEECHHHHHHHHH KFRPQLAETGGSIIIVSSISGLKANIGNPAYAASKAGAISLTKSLGQAFAADGIRVNGLA HCCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCEEECCCC PGLVDTKLTKVTTAHPQRLEGAIANIPQRRMGTPADMAGAAIFLASPLASYVTGHTLVVD CCCCCCHHHEEECCCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEC GGLSL CCCCC >Mature Secondary Structure MMDDTDFTGRRVLVVGGSSGIGNGIAQAFRDRGAEVHVWGTRANAAGYDPAEGSDLAGLG CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCC YTCVDVGSPDAIEAAPAPFPALDVLVLCQGTVVYKRGEFEREGWDKVMAVNLDSLMHCSR EEEEECCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCEEEEECHHHHHHHHH KFRPQLAETGGSIIIVSSISGLKANIGNPAYAASKAGAISLTKSLGQAFAADGIRVNGLA HCCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCEEECCCC PGLVDTKLTKVTTAHPQRLEGAIANIPQRRMGTPADMAGAAIFLASPLASYVTGHTLVVD CCCCCCHHHEEECCCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEC GGLSL CCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10192388; 10684935; 10871362 [H]