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The map label for this gene is mas [H]

Identifier: 87200463

GI number: 87200463

Start: 2639757

End: 2640728

Strand: Reverse

Name: mas [H]

Synonym: Saro_2450

Alternate gene names: 87200463

Gene position: 2640728-2639757 (Counterclockwise)

Preceding gene: 87200464

Following gene: 87200461

Centisome position: 74.14

GC content: 66.77

Gene sequence:

>972_bases
ATGAAGCAGTTCGCGCTTGCCGAACTGGTGGGGGCGGCCAGCGGCCGTATCGTGGATACCGCCCTGCCGCAGCCCGCATC
GGGCGAGGTCCGAGTGCGGGTCGAGGCGGTTGGTCTCGGCTTTGTCGATGATCTCATTGTTTCAGGCCGCTACCAATGGA
AGCCGCAATTGCCGTTCGTGCCGGGGGGCGAAATCGTCGGTACGGTTGAGGCAGTTGGGGAAGGCGTACAGGGCCTGACC
ACTGGTACCCGCGTGGCGGCATGGCGCATGGGCGGTGGGCTTTGCGAATATTGCACGCTCCCGGCCGGATATCTCGTCCC
CGTTCCGGCCCCGCTTGCGTCGGCAGATGCAGCCGGGATGGTGCTCGACTATGCCACGGCGGACTATGCCCTCATCGGCA
GGGGCCAATTGCGCAAGGGCGACACCGTCTTCGTGCTAGGGGCAACGGGCGGCGTGGGCGGCGCGGCAGTCCGCATCGCG
AGAGCGGCAGGCGCAGAAGTCATCGCTGGCGTCTCGAACCTGTCGCAGGGCGATAAAGTGCTCGCCGATGGCGCTAGTGC
AGTCGTCGACTGCTCGGCTCCGGACTGGCGCGACCAACTGCGTGGACACCCGCTCGATCTGGTTTTCGATCCCTTGGGTG
GCGCATTCACCGAACCCGCCTTCCGTTCGCTCGGAAAGCTGGGGCGGCATCTCGTGGTGGGCTTCGCTGCGGGCGGTATC
CCGGCATTGCCGGTCAATCTTCCCCTCCTCAAGAGCGCATCGCTCGTCGGCGTCGATGTGCGCTTTTTTGCCGAGTCTGA
TCCGGAGGGGTTCCGGCAGCGGCTCGCGCTGGTCTTCGATCAGGCGGCACGCGGGAGCCTGCGGCCCCCGGAAACGCTCT
GCTTCAGCCTTGGCGAGGCCGCCGCCGCCTTTGCCGCACTCACCCGACGCGGCCGGGGCGGCAAAGTGGTCGTCTGCCCG
CAATTGTCCTGA

Upstream 100 bases:

>100_bases
AACTGCCTCAGATGCAGGTCGACACGGGCGGTGCTTGCTGGCGCGAGAATTTCCTGTTCCGTGGCCTGACCGGCCTTGAA
GCCAGGTGGCCCGCGCAGGC

Downstream 100 bases:

>100_bases
ACCGGCTGTCGAGTGCCCGCAACGTGGCGTGTTCGATCCCTGCTCAGAGCACCAGCATCGCCGAACCCAGCGCCATGAAG
AAGCTGACCACCGTCGCGAC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKQFALAELVGAASGRIVDTALPQPASGEVRVRVEAVGLGFVDDLIVSGRYQWKPQLPFVPGGEIVGTVEAVGEGVQGLT
TGTRVAAWRMGGGLCEYCTLPAGYLVPVPAPLASADAAGMVLDYATADYALIGRGQLRKGDTVFVLGATGGVGGAAVRIA
RAAGAEVIAGVSNLSQGDKVLADGASAVVDCSAPDWRDQLRGHPLDLVFDPLGGAFTEPAFRSLGKLGRHLVVGFAAGGI
PALPVNLPLLKSASLVGVDVRFFAESDPEGFRQRLALVFDQAARGSLRPPETLCFSLGEAAAAFAALTRRGRGGKVVVCP
QLS

Sequences:

>Translated_323_residues
MKQFALAELVGAASGRIVDTALPQPASGEVRVRVEAVGLGFVDDLIVSGRYQWKPQLPFVPGGEIVGTVEAVGEGVQGLT
TGTRVAAWRMGGGLCEYCTLPAGYLVPVPAPLASADAAGMVLDYATADYALIGRGQLRKGDTVFVLGATGGVGGAAVRIA
RAAGAEVIAGVSNLSQGDKVLADGASAVVDCSAPDWRDQLRGHPLDLVFDPLGGAFTEPAFRSLGKLGRHLVVGFAAGGI
PALPVNLPLLKSASLVGVDVRFFAESDPEGFRQRLALVFDQAARGSLRPPETLCFSLGEAAAAFAALTRRGRGGKVVVCP
QLS
>Mature_323_residues
MKQFALAELVGAASGRIVDTALPQPASGEVRVRVEAVGLGFVDDLIVSGRYQWKPQLPFVPGGEIVGTVEAVGEGVQGLT
TGTRVAAWRMGGGLCEYCTLPAGYLVPVPAPLASADAAGMVLDYATADYALIGRGQLRKGDTVFVLGATGGVGGAAVRIA
RAAGAEVIAGVSNLSQGDKVLADGASAVVDCSAPDWRDQLRGHPLDLVFDPLGGAFTEPAFRSLGKLGRHLVVGFAAGGI
PALPVNLPLLKSASLVGVDVRFFAESDPEGFRQRLALVFDQAARGSLRPPETLCFSLGEAAAAFAALTRRGRGGKVVVCP
QLS

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=307, Percent_Identity=30.9446254071661, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI13236495, Length=307, Percent_Identity=30.9446254071661, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI18379349, Length=211, Percent_Identity=32.2274881516588, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI24308257, Length=237, Percent_Identity=29.1139240506329, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI194239676, Length=185, Percent_Identity=35.1351351351351, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI22538446, Length=318, Percent_Identity=28.6163522012579, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI22538444, Length=318, Percent_Identity=28.6163522012579, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI28557745, Length=291, Percent_Identity=27.8350515463918, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI67078404, Length=295, Percent_Identity=26.4406779661017, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI41872631, Length=305, Percent_Identity=26.5573770491803, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI67078406, Length=280, Percent_Identity=26.4285714285714, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790485, Length=232, Percent_Identity=29.3103448275862, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787863, Length=233, Percent_Identity=27.8969957081545, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=186, Percent_Identity=29.5698924731183, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=318, Percent_Identity=24.2138364779874, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19920632, Length=249, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI221330659, Length=249, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24581345, Length=252, Percent_Identity=27.3809523809524, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550423, Length=245, Percent_Identity=28.1632653061224, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 33146; Mature: 33146

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFALAELVGAASGRIVDTALPQPASGEVRVRVEAVGLGFVDDLIVSGRYQWKPQLPFV
CCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEECCCHHHHHHHCCCEECCCCCCCC
PGGEIVGTVEAVGEGVQGLTTGTRVAAWRMGGGLCEYCTLPAGYLVPVPAPLASADAAGM
CCCCEEEEHHHHCCCCCCCCCCCEEEEEECCCCEEHHHHCCCCCEEECCCCCCCCCCCCE
VLDYATADYALIGRGQLRKGDTVFVLGATGGVGGAAVRIARAAGAEVIAGVSNLSQGDKV
EEEECCCCEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCEE
LADGASAVVDCSAPDWRDQLRGHPLDLVFDPLGGAFTEPAFRSLGKLGRHLVVGFAAGGI
EECCCCEEEECCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCC
PALPVNLPLLKSASLVGVDVRFFAESDPEGFRQRLALVFDQAARGSLRPPETLCFSLGEA
CCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AAAFAALTRRGRGGKVVVCPQLS
HHHHHHHHHCCCCCEEEEECCCC
>Mature Secondary Structure
MKQFALAELVGAASGRIVDTALPQPASGEVRVRVEAVGLGFVDDLIVSGRYQWKPQLPFV
CCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEECCCHHHHHHHCCCEECCCCCCCC
PGGEIVGTVEAVGEGVQGLTTGTRVAAWRMGGGLCEYCTLPAGYLVPVPAPLASADAAGM
CCCCEEEEHHHHCCCCCCCCCCCEEEEEECCCCEEHHHHCCCCCEEECCCCCCCCCCCCE
VLDYATADYALIGRGQLRKGDTVFVLGATGGVGGAAVRIARAAGAEVIAGVSNLSQGDKV
EEEECCCCEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCEE
LADGASAVVDCSAPDWRDQLRGHPLDLVFDPLGGAFTEPAFRSLGKLGRHLVVGFAAGGI
EECCCCEEEECCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCC
PALPVNLPLLKSASLVGVDVRFFAESDPEGFRQRLALVFDQAARGSLRPPETLCFSLGEA
CCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AAAFAALTRRGRGGKVVVCPQLS
HHHHHHHHHCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]