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The map label for this gene is exuT [H]

Identifier: 87200461

GI number: 87200461

Start: 2637286

End: 2638515

Strand: Reverse

Name: exuT [H]

Synonym: Saro_2448

Alternate gene names: 87200461

Gene position: 2638515-2637286 (Counterclockwise)

Preceding gene: 87200463

Following gene: 87200459

Centisome position: 74.08

GC content: 64.96

Gene sequence:

>1230_bases
ATGACGGACGGTCGGAAAGGCGGGATCACCCGCGGGGCTGCGGTGGCGCTGGTCGCGCTGCTGTTCCTCGGCAACGCGCT
CAACTACGTGGATCGGCAGGTGCTCGCCCTGCTCAAGCCCACGCTCGAGGCGGAGTTCGGCTGGACCGATGCCGACTATG
CCCATCTCGGCTCCTCGTTCCAGATCGCTGCGGCCGGTACGCTCCTGTTCGTCGGCTGGTTCGTCGACAGGCTCGGCGTG
CGCATCGCCTATGCTGTGGCGGTCACGGTGTGGAGTGCGGCCGGCATGGCCCACGCTCTCGCGCAGACCGTGCAGCAGTT
CGTCACCGCCCGCATTGTGCTGGCTGCCGGCGAGTCTGTCAGCACTCCTGCCGGGCTCAAGGCTGCGGCAACCTATCTTC
CTGTCAGGCAAAGAAATTTCGCCATCGGCCTGATAAATACCGCGCCAAACATCGGCGCGATCCTCACGCCGCTTTTGATT
CCGCCCTTTGCGCTTGCGTTTGGCTGGAAGGCTGCGTTCGTCGTGACCGGGGCGCTGGGCTTCCTGTGGCTCGCTGGCTG
GTGGTTCGGCACTCGCGGTCTCCAGCCTGTCGGCAATGTACCCGAGCGCGCCCGCGTGCCATGGGGCGAGTTGCTGTCCG
ATCGCCGCACCTGGACCGTCATTGGTGCCAAGTTCTGCACGGATGCCGTCTGGTGGTTCGTGCTGTTCTGGATGCCCGAC
TTCTTCAACCGCCAGTTCGGTCTCAGCCAGGGGCAACTTGGCTGGCCCATCGCGATCATTTTCACCCTTGCGGCATTGGG
GGCGCTGACGTCGGGTGGCCTCTACCCGATCCTGCTGGCGCGCGGGATGAGCGTGAACGCCGCGCGCAAGACCTCGATGC
TGTTCTACGCGCTGGTCGTCCTTGCGATGCCGCTGTCGCTCCAGACTGGCAACCCCTGGCTCGCCGCCGTTCTCATCGGC
CTCGGCCTTTTTGCGCATCAGGGTTTCTCCACGAATGTCTTCGGCATGACCGCCGACATCGTTCCTGCCACCCGCGTCGC
CAGCGTGATCGCGCTCGGTGCGATCGCCGGCAATCTTTCGGGAACTGGCATCATCGAGTTCGCCGGCTGGTCGCTGACCA
ACGGCCTCGGTTACGTCCCGATGTTCGCGATCTGCGGCAGCGCCTATCTGGTTGCGCTGGCGTTCATCCACCTGATGCTG
CCGAAGCTGCAACTGTCGGCGGGAGAGTAG

Upstream 100 bases:

>100_bases
TGTGTCCTACGGTGTCATATAATGCTTCCCTTACGCTCCCGGTCGGCTATCGTGCAAGCGGGAAGCGGTGCAAAAGCACT
GTTCCGTGGGAGAAAGTGCA

Downstream 100 bases:

>100_bases
CGGAGCCGACGGCCGCCCTGCGCCCCCGCGAAGGCGGGGGCCTTGGTCTCGGCACTGAACTCCGCCAGAACTTCCGAAAA
CTCCCGCCTGCAAAGGCGAA

Product: major facilitator transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTDGRKGGITRGAAVALVALLFLGNALNYVDRQVLALLKPTLEAEFGWTDADYAHLGSSFQIAAAGTLLFVGWFVDRLGV
RIAYAVAVTVWSAAGMAHALAQTVQQFVTARIVLAAGESVSTPAGLKAAATYLPVRQRNFAIGLINTAPNIGAILTPLLI
PPFALAFGWKAAFVVTGALGFLWLAGWWFGTRGLQPVGNVPERARVPWGELLSDRRTWTVIGAKFCTDAVWWFVLFWMPD
FFNRQFGLSQGQLGWPIAIIFTLAALGALTSGGLYPILLARGMSVNAARKTSMLFYALVVLAMPLSLQTGNPWLAAVLIG
LGLFAHQGFSTNVFGMTADIVPATRVASVIALGAIAGNLSGTGIIEFAGWSLTNGLGYVPMFAICGSAYLVALAFIHLML
PKLQLSAGE

Sequences:

>Translated_409_residues
MTDGRKGGITRGAAVALVALLFLGNALNYVDRQVLALLKPTLEAEFGWTDADYAHLGSSFQIAAAGTLLFVGWFVDRLGV
RIAYAVAVTVWSAAGMAHALAQTVQQFVTARIVLAAGESVSTPAGLKAAATYLPVRQRNFAIGLINTAPNIGAILTPLLI
PPFALAFGWKAAFVVTGALGFLWLAGWWFGTRGLQPVGNVPERARVPWGELLSDRRTWTVIGAKFCTDAVWWFVLFWMPD
FFNRQFGLSQGQLGWPIAIIFTLAALGALTSGGLYPILLARGMSVNAARKTSMLFYALVVLAMPLSLQTGNPWLAAVLIG
LGLFAHQGFSTNVFGMTADIVPATRVASVIALGAIAGNLSGTGIIEFAGWSLTNGLGYVPMFAICGSAYLVALAFIHLML
PKLQLSAGE
>Mature_408_residues
TDGRKGGITRGAAVALVALLFLGNALNYVDRQVLALLKPTLEAEFGWTDADYAHLGSSFQIAAAGTLLFVGWFVDRLGVR
IAYAVAVTVWSAAGMAHALAQTVQQFVTARIVLAAGESVSTPAGLKAAATYLPVRQRNFAIGLINTAPNIGAILTPLLIP
PFALAFGWKAAFVVTGALGFLWLAGWWFGTRGLQPVGNVPERARVPWGELLSDRRTWTVIGAKFCTDAVWWFVLFWMPDF
FNRQFGLSQGQLGWPIAIIFTLAALGALTSGGLYPILLARGMSVNAARKTSMLFYALVVLAMPLSLQTGNPWLAAVLIGL
GLFAHQGFSTNVFGMTADIVPATRVASVIALGAIAGNLSGTGIIEFAGWSLTNGLGYVPMFAICGSAYLVALAFIHLMLP
KLQLSAGE

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=340, Percent_Identity=22.0588235294118, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI2367193, Length=388, Percent_Identity=26.2886597938144, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87082320, Length=411, Percent_Identity=26.0340632603406, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI2367379, Length=417, Percent_Identity=26.1390887290168, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789515, Length=398, Percent_Identity=22.1105527638191, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789152, Length=380, Percent_Identity=22.1052631578947, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43406; Mature: 43275

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGRKGGITRGAAVALVALLFLGNALNYVDRQVLALLKPTLEAEFGWTDADYAHLGSSF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCE
QIAAAGTLLFVGWFVDRLGVRIAYAVAVTVWSAAGMAHALAQTVQQFVTARIVLAAGESV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
STPAGLKAAATYLPVRQRNFAIGLINTAPNIGAILTPLLIPPFALAFGWKAAFVVTGALG
CCCCCHHHHHHHCCEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FLWLAGWWFGTRGLQPVGNVPERARVPWGELLSDRRTWTVIGAKFCTDAVWWFVLFWMPD
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHH
FFNRQFGLSQGQLGWPIAIIFTLAALGALTSGGLYPILLARGMSVNAARKTSMLFYALVV
HHCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
LAMPLSLQTGNPWLAAVLIGLGLFAHQGFSTNVFGMTADIVPATRVASVIALGAIAGNLS
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCC
GTGIIEFAGWSLTNGLGYVPMFAICGSAYLVALAFIHLMLPKLQLSAGE
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDGRKGGITRGAAVALVALLFLGNALNYVDRQVLALLKPTLEAEFGWTDADYAHLGSSF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCE
QIAAAGTLLFVGWFVDRLGVRIAYAVAVTVWSAAGMAHALAQTVQQFVTARIVLAAGESV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
STPAGLKAAATYLPVRQRNFAIGLINTAPNIGAILTPLLIPPFALAFGWKAAFVVTGALG
CCCCCHHHHHHHCCEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FLWLAGWWFGTRGLQPVGNVPERARVPWGELLSDRRTWTVIGAKFCTDAVWWFVLFWMPD
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHH
FFNRQFGLSQGQLGWPIAIIFTLAALGALTSGGLYPILLARGMSVNAARKTSMLFYALVV
HHCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
LAMPLSLQTGNPWLAAVLIGLGLFAHQGFSTNVFGMTADIVPATRVASVIALGAIAGNLS
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCC
GTGIIEFAGWSLTNGLGYVPMFAICGSAYLVALAFIHLMLPKLQLSAGE
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]