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The map label for this gene is ycsN [H]

Identifier: 87200457

GI number: 87200457

Start: 2630492

End: 2631406

Strand: Reverse

Name: ycsN [H]

Synonym: Saro_2444

Alternate gene names: 87200457

Gene position: 2631406-2630492 (Counterclockwise)

Preceding gene: 87200458

Following gene: 87200456

Centisome position: 73.88

GC content: 66.78

Gene sequence:

>915_bases
ATGAGCGATCTGCCCCTGCCGCCTGCCTTTCGCCAACTCGGCCACAGCGGGATTGCCGTGTCCCCGATCGCATGGGGCAT
GTGGCGCCTCGCCGAGAACGGGCGCACCCCCGCCGACGCGGCAAAGCTCGTCCACGCGGCGCTCGATGCGGGGATCAACT
TCCTCGACACGGCCGACATCTACGGCTTCGACGGCTCGGCGGGTTTTGGCGACGCGGAAGCACTGCTGGGCGAAGTCCTC
GCGGCCGAGCCAGCCCTGCGCGAACGCATGATTCTTGCCACCAAGGGCGGCATCCTTCCTCCGTTGCCCTACGACCAGAG
CGCCGACTACCTGCGCAAGGCCATCGACGATTCCCTTGCCCGGCTGAAGGTCGATGTGATCGACCTGTGGCAGATCCACC
GCCCCGACATCCTGGCCCATCCCTATGAAGTCGCGCGTGTGCTCGACGATGCGGTTTCGTCAGGCAAGGTCCGCGCGCTT
GGCGTCTCGAACTTCACCAAGGACCAGATCGCCGCGCTCAACCACTTCCTTGGCGAAAAGCTGGCGACGACCCAGCCCGA
GATCAGCCCCTTGCGCATCGACTGCTTCGAGAACGGCGAACTTGATCAGGCGATGATGCTCGGCCTGACGCCGATGGCGT
GGTCGCCGCTTGGCGGAGGCCGTCTTGCCTCACCCCAGACGGCGCGGGACAAGGCTGTTGCCGACGCGCTCGATGCCGTC
GCGCAGGCGCAGGGCGTTTCGCGCACTGTCGCCGCCTATTCGTGGCTCATGGCGCATCCGGCCGGGATCGTCCCGATCAT
TGGATCGCAACAGGCCGCGCGCATCGCCGAAGGGGCCGAAGCGCTGAAAGTCCGCTGGAACCGGCAGGACTGGTATGCCG
TGCTGGTAGCGGCGCGGGGAGAGCGGCTCCCCTAA

Upstream 100 bases:

>100_bases
CGACGGAAATCCTCATTGCCGGGGGCGACATCACCCACCGCCGGCTTCCCCATACTCTCGTAGAGCGCGCGTCGGTCGCG
CCTCCAGCCAGGACATCTTC

Downstream 100 bases:

>100_bases
GGGCGGGAGCCAGGTTGAAGCCGCCTGCCGCTCCGGCGGCGGGCATGTCTGGATCATGCGACGGACGGCGCCGTGTTGCG
GTTTTGCCGATGGAGAGTTG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSDLPLPPAFRQLGHSGIAVSPIAWGMWRLAENGRTPADAAKLVHAALDAGINFLDTADIYGFDGSAGFGDAEALLGEVL
AAEPALRERMILATKGGILPPLPYDQSADYLRKAIDDSLARLKVDVIDLWQIHRPDILAHPYEVARVLDDAVSSGKVRAL
GVSNFTKDQIAALNHFLGEKLATTQPEISPLRIDCFENGELDQAMMLGLTPMAWSPLGGGRLASPQTARDKAVADALDAV
AQAQGVSRTVAAYSWLMAHPAGIVPIIGSQQAARIAEGAEALKVRWNRQDWYAVLVAARGERLP

Sequences:

>Translated_304_residues
MSDLPLPPAFRQLGHSGIAVSPIAWGMWRLAENGRTPADAAKLVHAALDAGINFLDTADIYGFDGSAGFGDAEALLGEVL
AAEPALRERMILATKGGILPPLPYDQSADYLRKAIDDSLARLKVDVIDLWQIHRPDILAHPYEVARVLDDAVSSGKVRAL
GVSNFTKDQIAALNHFLGEKLATTQPEISPLRIDCFENGELDQAMMLGLTPMAWSPLGGGRLASPQTARDKAVADALDAV
AQAQGVSRTVAAYSWLMAHPAGIVPIIGSQQAARIAEGAEALKVRWNRQDWYAVLVAARGERLP
>Mature_303_residues
SDLPLPPAFRQLGHSGIAVSPIAWGMWRLAENGRTPADAAKLVHAALDAGINFLDTADIYGFDGSAGFGDAEALLGEVLA
AEPALRERMILATKGGILPPLPYDQSADYLRKAIDDSLARLKVDVIDLWQIHRPDILAHPYEVARVLDDAVSSGKVRALG
VSNFTKDQIAALNHFLGEKLATTQPEISPLRIDCFENGELDQAMMLGLTPMAWSPLGGGRLASPQTARDKAVADALDAVA
QAQGVSRTVAAYSWLMAHPAGIVPIIGSQQAARIAEGAEALKVRWNRQDWYAVLVAARGERLP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=309, Percent_Identity=22.6537216828479, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=22.6537216828479, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI27436962, Length=310, Percent_Identity=20.9677419354839, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27436964, Length=219, Percent_Identity=23.7442922374429, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI27436966, Length=308, Percent_Identity=20.7792207792208, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI48994888, Length=301, Percent_Identity=37.8737541528239, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI87081735, Length=306, Percent_Identity=29.7385620915033, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789375, Length=306, Percent_Identity=27.4509803921569, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788081, Length=270, Percent_Identity=24.8148148148148, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789199, Length=330, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788070, Length=337, Percent_Identity=26.4094955489614, Blast_Score=68, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323998, Length=343, Percent_Identity=26.530612244898, Blast_Score=82, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319958, Length=282, Percent_Identity=25.886524822695, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646155, Length=270, Percent_Identity=29.2592592592593, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24646159, Length=171, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32555; Mature: 32423

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPLPPAFRQLGHSGIAVSPIAWGMWRLAENGRTPADAAKLVHAALDAGINFLDTADI
CCCCCCCHHHHHCCCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEECCCC
YGFDGSAGFGDAEALLGEVLAAEPALRERMILATKGGILPPLPYDQSADYLRKAIDDSLA
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
RLKVDVIDLWQIHRPDILAHPYEVARVLDDAVSSGKVRALGVSNFTKDQIAALNHFLGEK
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
LATTQPEISPLRIDCFENGELDQAMMLGLTPMAWSPLGGGRLASPQTARDKAVADALDAV
HHCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AQAQGVSRTVAAYSWLMAHPAGIVPIIGSQQAARIAEGAEALKVRWNRQDWYAVLVAARG
HHHHCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCHHHHEEEECCCCEEEEEEECCC
ERLP
CCCC
>Mature Secondary Structure 
SDLPLPPAFRQLGHSGIAVSPIAWGMWRLAENGRTPADAAKLVHAALDAGINFLDTADI
CCCCCCHHHHHCCCCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEECCCC
YGFDGSAGFGDAEALLGEVLAAEPALRERMILATKGGILPPLPYDQSADYLRKAIDDSLA
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
RLKVDVIDLWQIHRPDILAHPYEVARVLDDAVSSGKVRALGVSNFTKDQIAALNHFLGEK
HHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
LATTQPEISPLRIDCFENGELDQAMMLGLTPMAWSPLGGGRLASPQTARDKAVADALDAV
HHCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AQAQGVSRTVAAYSWLMAHPAGIVPIIGSQQAARIAEGAEALKVRWNRQDWYAVLVAARG
HHHHCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCHHHHEEEECCCCEEEEEEECCC
ERLP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]