Click here to switch to the map view.

The map label for this gene is ccpA [H]

Identifier: 87200458

GI number: 87200458

Start: 2631403

End: 2632416

Strand: Reverse

Name: ccpA [H]

Synonym: Saro_2445

Alternate gene names: 87200458

Gene position: 2632416-2631403 (Counterclockwise)

Preceding gene: 87200459

Following gene: 87200457

Centisome position: 73.91

GC content: 64.99

Gene sequence:

>1014_bases
ATGAGTGAGCGGGCGAACATCAGGGACGTGGCGGCCAAGGCGGGCGTGGCGGTGAAGACCGTCAGCCGGGTCCTCAACGG
CCACCCCTATGTCAGCGCCGATACCAAGGCGCGGGTCGAGGAGGCTATGCGCGCGCTCGATTTCCGGCCAAGCGTGGCCG
CCCGCATCCTGTCAGGGGCGAAGTCGAACCAGATCGCGCTGATCTACGACAATCACAGCCCCTACTACATGTTTCAGATC
CAGACCGGGTGCTGGGACTTCTGCCGCGCCAACAACATCCGCCTGCTCGCCCAGCCGGTCGACGTGGCCGACCCGCAGGT
GGGCGAACAGGTGCGCGGTCTCGTCAGCGAGACGCATGTCGATGGGATCATCCTGTCCTCGCCGGTAACCGATTGCGATC
CTGTGCTGCGTGCGCTCGAGGCGATGGACATTCCCTTCGTGCGTATCTCGCCCGGTACCAATCATGCACTGACCAGTTCG
GTGTTCATGGACGACGCGCAAGCCGCAGACGACATGACCACGCACCTGATCAATGCCGGGCACCGCCGTATCGGCTTTAT
CAAGGGCCATCCCAACCACATGGCGTCGGATGACCGCCTGTTCGGTTACCGTCGCGCTCTCGACCGGGCAGGGCTGCCCT
ACGATCCGGTGCTTGTCTGCGAAGGCGAGTTCGATTTCGATTCCGGTACGCGCGGGGGCAGGGCCCTGCTCGACCTCCCG
AACCGCCCGACCGCCATCTTTGCTTCGAACGACGACATGGCGGCTGGTGTCCTGGCCGTCGCGCACGACCGCGGCATCAA
CGTGCCGGGCGAACTTTCGGTCGCCGGCTTCGACGATACCACGCTCGCCCGTACGGTCTGGCCGCCGCTGACGACCATCC
ACCAGCCTATGGTCGAACTGGCCAGGACGGCGACGGAAATCCTCATTGCCGGGGGCGACATCACCCACCGCCGGCTTCCC
CATACTCTCGTAGAGCGCGCGTCGGTCGCGCCTCCAGCCAGGACATCTTCATGA

Upstream 100 bases:

>100_bases
CGCACGATATCTCCGCCCCCATCGGGCAGCCGCCGGCATTCTACCGTCCGGACAGCGCCTTCGCGTCGCTGTTCGCGGGA
CTGAAGGGGGTGCTTGAAGG

Downstream 100 bases:

>100_bases
GCGATCTGCCCCTGCCGCCTGCCTTTCGCCAACTCGGCCACAGCGGGATTGCCGTGTCCCCGATCGCATGGGGCATGTGG
CGCCTCGCCGAGAACGGGCG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSERANIRDVAAKAGVAVKTVSRVLNGHPYVSADTKARVEEAMRALDFRPSVAARILSGAKSNQIALIYDNHSPYYMFQI
QTGCWDFCRANNIRLLAQPVDVADPQVGEQVRGLVSETHVDGIILSSPVTDCDPVLRALEAMDIPFVRISPGTNHALTSS
VFMDDAQAADDMTTHLINAGHRRIGFIKGHPNHMASDDRLFGYRRALDRAGLPYDPVLVCEGEFDFDSGTRGGRALLDLP
NRPTAIFASNDDMAAGVLAVAHDRGINVPGELSVAGFDDTTLARTVWPPLTTIHQPMVELARTATEILIAGGDITHRRLP
HTLVERASVAPPARTSS

Sequences:

>Translated_337_residues
MSERANIRDVAAKAGVAVKTVSRVLNGHPYVSADTKARVEEAMRALDFRPSVAARILSGAKSNQIALIYDNHSPYYMFQI
QTGCWDFCRANNIRLLAQPVDVADPQVGEQVRGLVSETHVDGIILSSPVTDCDPVLRALEAMDIPFVRISPGTNHALTSS
VFMDDAQAADDMTTHLINAGHRRIGFIKGHPNHMASDDRLFGYRRALDRAGLPYDPVLVCEGEFDFDSGTRGGRALLDLP
NRPTAIFASNDDMAAGVLAVAHDRGINVPGELSVAGFDDTTLARTVWPPLTTIHQPMVELARTATEILIAGGDITHRRLP
HTLVERASVAPPARTSS
>Mature_336_residues
SERANIRDVAAKAGVAVKTVSRVLNGHPYVSADTKARVEEAMRALDFRPSVAARILSGAKSNQIALIYDNHSPYYMFQIQ
TGCWDFCRANNIRLLAQPVDVADPQVGEQVRGLVSETHVDGIILSSPVTDCDPVLRALEAMDIPFVRISPGTNHALTSSV
FMDDAQAADDMTTHLINAGHRRIGFIKGHPNHMASDDRLFGYRRALDRAGLPYDPVLVCEGEFDFDSGTRGGRALLDLPN
RPTAIFASNDDMAAGVLAVAHDRGINVPGELSVAGFDDTTLARTVWPPLTTIHQPMVELARTATEILIAGGDITHRRLPH
TLVERASVAPPARTSS

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789068, Length=336, Percent_Identity=31.25, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1790369, Length=305, Percent_Identity=33.1147540983607, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=33.1325301204819, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787948, Length=335, Percent_Identity=31.3432835820896, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789202, Length=346, Percent_Identity=34.393063583815, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788474, Length=336, Percent_Identity=32.7380952380952, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786540, Length=344, Percent_Identity=28.4883720930233, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1789456, Length=311, Percent_Identity=30.5466237942122, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI48994940, Length=314, Percent_Identity=26.1146496815287, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787906, Length=342, Percent_Identity=26.9005847953216, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790715, Length=312, Percent_Identity=25, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=25.2365930599369, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790689, Length=339, Percent_Identity=25.6637168141593, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36520; Mature: 36389

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERANIRDVAAKAGVAVKTVSRVLNGHPYVSADTKARVEEAMRALDFRPSVAARILSGA
CCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCC
KSNQIALIYDNHSPYYMFQIQTGCWDFCRANNIRLLAQPVDVADPQVGEQVRGLVSETHV
CCCEEEEEEECCCCEEEEEECCCCHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC
DGIILSSPVTDCDPVLRALEAMDIPFVRISPGTNHALTSSVFMDDAQAADDMTTHLINAG
CCEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHCC
HRRIGFIKGHPNHMASDDRLFGYRRALDRAGLPYDPVLVCEGEFDFDSGTRGGRALLDLP
CCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCEEEEECC
NRPTAIFASNDDMAAGVLAVAHDRGINVPGELSVAGFDDTTLARTVWPPLTTIHQPMVEL
CCCCEEEECCCCCHHHEEEEECCCCCCCCCCEEEECCCCCHHHHHHCCCHHHHHHHHHHH
ARTATEILIAGGDITHRRLPHTLVERASVAPPARTSS
HHHHHHEEEECCCCCHHHCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SERANIRDVAAKAGVAVKTVSRVLNGHPYVSADTKARVEEAMRALDFRPSVAARILSGA
CCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCC
KSNQIALIYDNHSPYYMFQIQTGCWDFCRANNIRLLAQPVDVADPQVGEQVRGLVSETHV
CCCEEEEEEECCCCEEEEEECCCCHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC
DGIILSSPVTDCDPVLRALEAMDIPFVRISPGTNHALTSSVFMDDAQAADDMTTHLINAG
CCEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHCC
HRRIGFIKGHPNHMASDDRLFGYRRALDRAGLPYDPVLVCEGEFDFDSGTRGGRALLDLP
CCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCEEEEECC
NRPTAIFASNDDMAAGVLAVAHDRGINVPGELSVAGFDDTTLARTVWPPLTTIHQPMVEL
CCCCEEEECCCCCHHHEEEEECCCCCCCCCCEEEECCCCCHHHHHHCCCHHHHHHHHHHH
ARTATEILIAGGDITHRRLPHTLVERASVAPPARTSS
HHHHHHEEEECCCCCHHHCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]