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The map label for this gene is gcvT [H]

Identifier: 87200417

GI number: 87200417

Start: 2571954

End: 2573342

Strand: Direct

Name: gcvT [H]

Synonym: Saro_2404

Alternate gene names: 87200417

Gene position: 2571954-2573342 (Clockwise)

Preceding gene: 87200416

Following gene: 87200418

Centisome position: 72.21

GC content: 63.35

Gene sequence:

>1389_bases
ATGTCCCAGACCCTAGAGCAGGTCATCCAGAACGCTGGTGATCTCGTGAACTTCGTCCGCAACCAGCAGGTCGGCCCCAA
CGTCTATCCCGGCGTTCCGGCGGAATACTCGAACTGGCGCAACGAACAGTGGGCCTGGGCGCACTCCGCAGTGCTCTACA
ACCAGTCGTACCACATGGTCGATCTGGCGGTTAAGGGTCCGGATGCGTTCAAGATGCTCGAACACCTCGGCATCAACTCG
TTCAAGAACTTCCAGCCGGATCGCGCCAAGCAGTTCGTCCCCGTCACGCCCGACGGCTATGTCATCGGCGACGTGATCCT
GTTCTATCTCGACGAGAACCATTTCAACCTCGTCGGTCGCGCGCCGACGATCGAATGGGTCGAATATCACGCCGCCAGCG
GCAACTGGAACGTCACCGTCGAACGTGACGAGCGTTGGGCCATGCGCACCGATGGCAAGCGCAATTCCTACCGCTTCCAG
ATCCAGGGCCCGAACGCGATGAAGATCATCGAGAAGGCCACCGGCAAGACCGCTCCGGATCTCAAGTTCTTCCACATGAC
CCGCATGACCATCGGCGGCAAGGAAGTGCGCGCGCTGCGCCACGGCATGGCCGGCCAGCCGGGCTTCGAGCTGATGGGTC
CGTGGGAAGACTACGGCGCTGTCCATGCCGCGCTGGTCGAGGCCGGCAAGGGGTTCCAGATGGCCCTCGTCGGCGGCCGC
GCCTATTCGTCGAACACGCTGGAATCGGGCTGGATCCCCTCGCCCTTCCCGGCGATCTACACCGGCGAGGCGCTGCGCCC
CTACCGCGAATGGCTCTCGGCCAATTCCTATGAAGCCAAGTGCTCGGTTGGCGGCAGCTATGTGCCCGAAACCATCGAGG
GCTACTACACCACGCCGTGGGATCTGGGTTACGGCCCCTTCGTCAAGTTCGACCATGACTTCATCGGTCGCGCCGCGCTC
GAGAAGATGGCGGCCGAAGGCAAGCACCGCACCAAGGTCACGCTCGCGCTCGACAACGAAGACGTGATGCGCGTCCAGTC
CTCGGCGCTCAGCAAGGGCGATCGCGCCAAGTTCATGGAATACCCGAGCGCGGTCTATTCGATGCACCCGTTCGACCAGG
TGCTTGCCGATGGCAAGATGGTCGGCCTCTCCACCTGGATCGGCTACACCGCCAACGAGGGCAAGTTCCTCACGCTGGCC
ATGATGGAGCCGGGTTACGTCGAACCGGGCACGCAAGTCAGCCTGCTCTGGGGCGAACCGAACGGCGGCACCACCAAGCC
CACCGTCGAACCCCACGTCCAGACCGAGATCAAGGCCACCGTCGCCGCCGTCCCCTACTCGGAAGTGGCGCGCGACAGCT
ACGCCGAGGGCTGGCGCACCAAGAAGTAA

Upstream 100 bases:

>100_bases
ACATTTTTTCGCCCAATTCATCATTCCGAACTTTTCAAGCACGCGAAAATAGGGCAAAGCGAATCCACATCCGCGAAATC
GCATCGGGAGAGCTTGAGAA

Downstream 100 bases:

>100_bases
GGCTACAGGTGCGAACCTGACAGCGAGAGCGCCGGCCCATCCCGACGGGCCCGGCGCTCTTTGCGTTGTAGCACTTCCTG
CGCTCCTAATGCCTCGTCAC

Product: glycine cleavage T protein (aminomethyl transferase)

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSQTLEQVIQNAGDLVNFVRNQQVGPNVYPGVPAEYSNWRNEQWAWAHSAVLYNQSYHMVDLAVKGPDAFKMLEHLGINS
FKNFQPDRAKQFVPVTPDGYVIGDVILFYLDENHFNLVGRAPTIEWVEYHAASGNWNVTVERDERWAMRTDGKRNSYRFQ
IQGPNAMKIIEKATGKTAPDLKFFHMTRMTIGGKEVRALRHGMAGQPGFELMGPWEDYGAVHAALVEAGKGFQMALVGGR
AYSSNTLESGWIPSPFPAIYTGEALRPYREWLSANSYEAKCSVGGSYVPETIEGYYTTPWDLGYGPFVKFDHDFIGRAAL
EKMAAEGKHRTKVTLALDNEDVMRVQSSALSKGDRAKFMEYPSAVYSMHPFDQVLADGKMVGLSTWIGYTANEGKFLTLA
MMEPGYVEPGTQVSLLWGEPNGGTTKPTVEPHVQTEIKATVAAVPYSEVARDSYAEGWRTKK

Sequences:

>Translated_462_residues
MSQTLEQVIQNAGDLVNFVRNQQVGPNVYPGVPAEYSNWRNEQWAWAHSAVLYNQSYHMVDLAVKGPDAFKMLEHLGINS
FKNFQPDRAKQFVPVTPDGYVIGDVILFYLDENHFNLVGRAPTIEWVEYHAASGNWNVTVERDERWAMRTDGKRNSYRFQ
IQGPNAMKIIEKATGKTAPDLKFFHMTRMTIGGKEVRALRHGMAGQPGFELMGPWEDYGAVHAALVEAGKGFQMALVGGR
AYSSNTLESGWIPSPFPAIYTGEALRPYREWLSANSYEAKCSVGGSYVPETIEGYYTTPWDLGYGPFVKFDHDFIGRAAL
EKMAAEGKHRTKVTLALDNEDVMRVQSSALSKGDRAKFMEYPSAVYSMHPFDQVLADGKMVGLSTWIGYTANEGKFLTLA
MMEPGYVEPGTQVSLLWGEPNGGTTKPTVEPHVQTEIKATVAAVPYSEVARDSYAEGWRTKK
>Mature_461_residues
SQTLEQVIQNAGDLVNFVRNQQVGPNVYPGVPAEYSNWRNEQWAWAHSAVLYNQSYHMVDLAVKGPDAFKMLEHLGINSF
KNFQPDRAKQFVPVTPDGYVIGDVILFYLDENHFNLVGRAPTIEWVEYHAASGNWNVTVERDERWAMRTDGKRNSYRFQI
QGPNAMKIIEKATGKTAPDLKFFHMTRMTIGGKEVRALRHGMAGQPGFELMGPWEDYGAVHAALVEAGKGFQMALVGGRA
YSSNTLESGWIPSPFPAIYTGEALRPYREWLSANSYEAKCSVGGSYVPETIEGYYTTPWDLGYGPFVKFDHDFIGRAALE
KMAAEGKHRTKVTLALDNEDVMRVQSSALSKGDRAKFMEYPSAVYSMHPFDQVLADGKMVGLSTWIGYTANEGKFLTLAM
MEPGYVEPGTQVSLLWGEPNGGTTKPTVEPHVQTEIKATVAAVPYSEVARDSYAEGWRTKK

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=291, Percent_Identity=24.7422680412371, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 51602; Mature: 51471

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTLEQVIQNAGDLVNFVRNQQVGPNVYPGVPAEYSNWRNEQWAWAHSAVLYNQSYHMV
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEEEEEEEECCCEEEE
DLAVKGPDAFKMLEHLGINSFKNFQPDRAKQFVPVTPDGYVIGDVILFYLDENHFNLVGR
EEEECCCHHHHHHHHCCCCCCCCCCCCHHCCEEECCCCCEEEEEEEEEEECCCCEEEEEC
APTIEWVEYHAASGNWNVTVERDERWAMRTDGKRNSYRFQIQGPNAMKIIEKATGKTAPD
CCCEEEEEEEECCCCEEEEEECCCCEEECCCCCCCCEEEEEECCCHHHHHHHHCCCCCCC
LKFFHMTRMTIGGKEVRALRHGMAGQPGFELMGPWEDYGAVHAALVEAGKGFQMALVGGR
EEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
AYSSNTLESGWIPSPFPAIYTGEALRPYREWLSANSYEAKCSVGGSYVPETIEGYYTTPW
CCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCC
DLGYGPFVKFDHDFIGRAALEKMAAEGKHRTKVTLALDNEDVMRVQSSALSKGDRAKFME
CCCCCCCEEECHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHH
YPSAVYSMHPFDQVLADGKMVGLSTWIGYTANEGKFLTLAMMEPGYVEPGTQVSLLWGEP
CCHHHHHCCCHHHHHCCCEEEEEEEEECEECCCCCEEEEEEECCCCCCCCCEEEEEEECC
NGGTTKPTVEPHVQTEIKATVAAVPYSEVARDSYAEGWRTKK
CCCCCCCCCCCCHHHHEEEEEEECCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SQTLEQVIQNAGDLVNFVRNQQVGPNVYPGVPAEYSNWRNEQWAWAHSAVLYNQSYHMV
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEEEEEEEECCCEEEE
DLAVKGPDAFKMLEHLGINSFKNFQPDRAKQFVPVTPDGYVIGDVILFYLDENHFNLVGR
EEEECCCHHHHHHHHCCCCCCCCCCCCHHCCEEECCCCCEEEEEEEEEEECCCCEEEEEC
APTIEWVEYHAASGNWNVTVERDERWAMRTDGKRNSYRFQIQGPNAMKIIEKATGKTAPD
CCCEEEEEEEECCCCEEEEEECCCCEEECCCCCCCCEEEEEECCCHHHHHHHHCCCCCCC
LKFFHMTRMTIGGKEVRALRHGMAGQPGFELMGPWEDYGAVHAALVEAGKGFQMALVGGR
EEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
AYSSNTLESGWIPSPFPAIYTGEALRPYREWLSANSYEAKCSVGGSYVPETIEGYYTTPW
CCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCC
DLGYGPFVKFDHDFIGRAALEKMAAEGKHRTKVTLALDNEDVMRVQSSALSKGDRAKFME
CCCCCCCEEECHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHH
YPSAVYSMHPFDQVLADGKMVGLSTWIGYTANEGKFLTLAMMEPGYVEPGTQVSLLWGEP
CCHHHHHCCCHHHHHCCCEEEEEEEEECEECCCCCEEEEEEECCCCCCCCCEEEEEEECC
NGGTTKPTVEPHVQTEIKATVAAVPYSEVARDSYAEGWRTKK
CCCCCCCCCCCCHHHHEEEEEEECCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA